Title:
TRANSFORMANT AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/138966
Kind Code:
A1
Abstract:
Provided are: a transformant capable of expressing a gene encoding an exogenous isoprenoid biosynthetic enzyme; and a method for producing isoprenoid or an isoprenoid precursor using the transformant. The method uses a transformant capable of expressing an isoprenoid biosynthetic enzyme gene with a promoter sequence obtained from oleaginous yeast.
Inventors:
KANAMOTO HIROSUKE (JP)
MISAWA NORIHIKO (JP)
MISAWA NORIHIKO (JP)
Application Number:
PCT/JP2017/034751
Publication Date:
August 02, 2018
Filing Date:
September 26, 2017
Export Citation:
Assignee:
KNC LABORATORIES CO LTD (JP)
International Classes:
C12N1/19; C12N1/15; C12N5/10; C12P5/00; C12N9/00; C12N9/12; C12N15/09
Domestic Patent References:
| WO2009132286A2 | 2009-10-29 | |||
| WO2015042306A1 | 2015-03-26 | |||
| WO2015011209A1 | 2015-01-29 | |||
| WO2015116781A2 | 2015-08-06 |
Foreign References:
| US20160138031A1 | 2016-05-19 |
Other References:
KANEKI, KOSUKE ET AL: "Development of a Terpene Production System Using Oleaginous Yeast Lipomyces starkeyi", ABSTRACTS OF THE 11TH ANNUAL MEETING OF THE SOCIETYOF GENOME MICROBIOLOGY, JAPAN, vol. 11, 2 March 2017 (2017-03-02), pages 93
MATTHAUS, F. ET AL.: "Production of Lycopene in the Non-Carotenoid-Producing Yeast Yarrowia lipolytica", APPL. ENVIRON. MICROBIOL., vol. 80, no. 5, March 2014 (2014-03-01), pages 1660 - 1669, XP055537228, ISSN: 0099-2240
SHIMADA, H. ET AL.: "Increased Carotenoid Production by the Food Yeast Candida utilis through Metabolic Engineering of the Isoprenoid Pathway", APPL. ENVIRON. MICROBIOL., vol. 64, no. 7, 1998, pages 2676 - 2680, XP055537449, ISSN: 0099-2240
WANG, Y. ET AL.: "Cloning and evaluation of different constitutive promoters in the oleaginous yeast Rhodosporidium toruloides", YEAST, vol. 33, no. 3, 14 January 2016 (2016-01-14), pages 99 - 106, XP055404515, ISSN: 0749-503X
MADZAK, C. ET AL.: "Yarrowia lipolytica: recent achievements in heterologous protein expression and pathway engineering", APPL. MICROBIOL. BIOTECHNOL., vol. 99, no. 11, 7 May 2015 (2015-05-07), pages 4559 - 4577, XP035502966, ISSN: 0175-7598
MATTHAUS, F. ET AL.: "Production of Lycopene in the Non-Carotenoid-Producing Yeast Yarrowia lipolytica", APPL. ENVIRON. MICROBIOL., vol. 80, no. 5, March 2014 (2014-03-01), pages 1660 - 1669, XP055537228, ISSN: 0099-2240
SHIMADA, H. ET AL.: "Increased Carotenoid Production by the Food Yeast Candida utilis through Metabolic Engineering of the Isoprenoid Pathway", APPL. ENVIRON. MICROBIOL., vol. 64, no. 7, 1998, pages 2676 - 2680, XP055537449, ISSN: 0099-2240
WANG, Y. ET AL.: "Cloning and evaluation of different constitutive promoters in the oleaginous yeast Rhodosporidium toruloides", YEAST, vol. 33, no. 3, 14 January 2016 (2016-01-14), pages 99 - 106, XP055404515, ISSN: 0749-503X
MADZAK, C. ET AL.: "Yarrowia lipolytica: recent achievements in heterologous protein expression and pathway engineering", APPL. MICROBIOL. BIOTECHNOL., vol. 99, no. 11, 7 May 2015 (2015-05-07), pages 4559 - 4577, XP035502966, ISSN: 0175-7598
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
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