TRETINOIN ALCOHOL-AMINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

Title:

TRETINOIN ALCOHOL-AMINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2024/012400

Kind Code:

A1

Abstract:

The present invention relates to a tretinoin alcohol-amine compound, which consists of tretinoin and an alcohol-amine compound, is liquid at normal temperature, has good water solubility/water dilution resistance and skin permeation effects, overcomes the limitations of tretinoin compounds in the field of preparation application in the prior art, and has a broad medicinal prospect.

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Inventors:

LIU ZHENYUN (CN)
HU TAO (CN)
LU XIQIANG (CN)
QI JIANPING (CN)
WU WEI (CN)
WU YUBO (CN)
CHEN LEI (CN)

Application Number:

PCT/CN2023/106535

Publication Date:

January 18, 2024

Filing Date:

July 10, 2023

Export Citation:

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Assignee:

NANJING INDETEK LABORATORY CO LTD (CN)
UNIV FUDAN (CN)

International Classes:

A61K31/203; C07C403/20; A61P17/00; A61P35/00

Domestic Patent References:

WO2005102296A2

2005-11-03

Foreign References:

CN101843584A	2010-09-29
CN103845738A	2014-06-11
CN101980999A	2011-02-23
CN101048375A	2007-10-03

Other References:

ANADOLU R. Y., SEN T., TARIMCI N: "0087. Improved efficacy and tolerability of retinoic acid in acne vulgaris: A new topical formulation with cyclodextrin complex", DIGEST OF THE WORLD CORE MEDICAL JOURNALS, vol. 1, no. 1, 15 January 2005 (2005-01-15), pages 44 - 45, XP093127688

Attorney, Agent or Firm:

BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)

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