TUMOR ANTIGEN PEPTIDES - UNIV SAPPORO MEDICAL

Title:

TUMOR ANTIGEN PEPTIDES

Document Type and Number:

WIPO Patent Application WO/2016/047715

Kind Code:

A1

Abstract:

The purpose of the present invention is to provide: a tumor antigen peptide presented specifically to cancer and cancer stem cells; a pharmaceutical composition useful in the prevention and/or treatment of cancer, the pharmaceutical composition containing the tumor antigen peptide as an active ingredient; and the like. The above problem is solved by providing: a partial peptide derived from BORIS belonging to isoform A or C or subfamily 5 or 6; a polynucleotide encoding this peptide; a pharmaceutical composition containing these as active ingredients; an agent for the prevention and/or treatment of cancer, the agent being characterized by inducing CTL; and the like.

Inventors:

TORIGOE TOSHIHIKO (JP)
ATSUYAMA ERI (JP)
OTAKA HIRONORI (JP)
NAKANO KAZUE (JP)
LI DONGLIANG (JP)
TOJI SHINGO (JP)
ASANO TAKUYA (JP)
HORIBE RYOTA (JP)
HIROHASHI YOSHIHIKO (JP)
SATO NORIYUKI (JP)
SAITO TSUYOSHI (JP)

Application Number:

PCT/JP2015/076994

Publication Date:

March 31, 2016

Filing Date:

September 24, 2015

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV SAPPORO MEDICAL (JP)
MED & BIOLOGICAL LAB CO LTD (JP)

International Classes:

C12N15/00; A61K35/76; A61K39/00; A61K48/00; A61P35/00; A61P37/04; C07K7/06; C12N5/0783; C12N5/10; C12N15/09; C12N15/11; C07K14/82

Foreign References:

JP2010502192A

2010-01-28

Other References:

ROMAGNOLI GIULIA ET AL.: "EVALUATION OF THE POTENTIAL ROLE OF THE NEW CANCER-TESTIS ANTIGEN BORIS FOR THE DEVELOPMENT OF NOVEL STRATEGIES OF IMMUNOTHERAPY OF CANCER", RAPPORTI ISTISAN, vol. 6, no. 50, 2006, pages 36 - 40, XP009501169
PUGACHEVA ELENA M. ET AL.: "The structural complexity of the human BORIS gene in gametogenesis and cancer", PLOS ONE, vol. 5, no. 11, 2010, pages e13872, XP055419657, Retrieved from the Internet [retrieved on 20151028]
See also references of EP 3199627A4