Title:
TUMOR SPECIFIC OLIGOSACCHARIDE SEQUENCES AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO2003016915
Kind Code:
A8
Abstract:
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present inventionis related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
Inventors:
NATUNEN JARI (FI)
TENEBERG SUSANN (SE)
KARLSSON KARL-ANDERS (SE)
SATOMAA TERO (FI)
HEISKANEN ANNAMARI (FI)
TENEBERG SUSANN (SE)
KARLSSON KARL-ANDERS (SE)
SATOMAA TERO (FI)
HEISKANEN ANNAMARI (FI)
Application Number:
PCT/FI2002/000681
Publication Date:
February 05, 2004
Filing Date:
August 20, 2002
Export Citation:
Assignee:
BIOTIE THERAPIES CORP (FI)
NATUNEN JARI (FI)
TENEBERG SUSANN (SE)
KARLSSON KARL-ANDERS (SE)
SATOMAA TERO (FI)
HEISKANEN ANNAMARI (FI)
NATUNEN JARI (FI)
TENEBERG SUSANN (SE)
KARLSSON KARL-ANDERS (SE)
SATOMAA TERO (FI)
HEISKANEN ANNAMARI (FI)
International Classes:
A23L1/305; A61K31/70; A61K38/17; A61K38/36; A61K38/45; A61K39/00; A61K39/385; A61K39/39; A61K39/395; A61K47/36; A61K47/48; A61P31/00; A61P35/00; A61P37/02; A61P37/04; C07H3/06; C07H5/06; C07K1/22; C07K2/00; C07K16/18; C07K16/32; C12P21/08; C12Q1/02; G01N30/00; G01N33/15; G01N33/50; G01N33/53; G01N33/574; A61B; (IPC1-7): G01N33/574; C07H5/06; A61K39/00; A61P35/00
Download PDF: