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Title:
USE OF ANTI-CTLA-4 ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2022/270612
Kind Code:
A1
Abstract:
The present disclosure provides an anti-CTLA-4 antibody and methods for producing and using same. The present disclosure also provides: a nucleic acid encoding said anti-CTLA-4 antibody; and host cells including said nucleic acid. The present disclosure further provides: a polypeptide including a variant Fc region that includes an amino acid modification in a novel Fc region; and a production method and method for using said polypeptide.

Inventors:
KATADA HITOSHI (SG)
TATSUMI KANAKO (JP)
MATSUDA YUTAKA (JP)
SHIMIZU SHUN (JP)
KAMIMURA MASAKI (JP)
KOMORI YASUNORI (JP)
HORI YUJI (JP)
IGAWA TOMOYUKI (JP)
KAWAUCHI HIROKI (JP)
HAYASHI HIROKI (JP)
SAKAGUCHI SHIMON (JP)
SUSUMU HIROAKI (JP)
Application Number:
PCT/JP2022/025222
Publication Date:
December 29, 2022
Filing Date:
June 24, 2022
Export Citation:
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Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
UNIV OSAKA (JP)
International Classes:
C07K16/28; A61K39/395; A61K45/00; A61P35/00; A61P43/00; C12N15/13
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Attorney, Agent or Firm:
HARUNA, Masao et al. (JP)
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