Title:
USE OF ANTI-IDIOPATHIC PULMONARY FIBROSIS DRUG NINTEDANIB IN TREATMENT OF TUBERCULOSIS
Document Type and Number:
WIPO Patent Application WO/2023/207398
Kind Code:
A1
Abstract:
Provided is use of nintedanib or a pharmaceutically acceptable salt thereof in preparing a drug for the treatment of tuberculosis. The nintedanib or the pharmaceutically acceptable salt thereof is used in combination with other anti-tuberculosis drugs for the treatment of tuberculosis, or used as an adjuvant drug for the treatment of tuberculosis, wherein the other anti-tuberculosis drugs are selected from: rifampicin, isoniazide, pyrazinamide, ethambutol, fluoroquinolone, streptomycin, kanamycin, amikacin, capreomycin, sodium aminosalicylate, ethionamide, cycloserine, clofazimine, and linezolid.
Inventors:
LU YU (CN)
CHEN XIAOYOU (CN)
QI XUETING (CN)
ZHENG LUYAO (CN)
FU LEI (CN)
ZHANG WEIYAN (CN)
WANG NING (CN)
CHEN XIAOYOU (CN)
QI XUETING (CN)
ZHENG LUYAO (CN)
FU LEI (CN)
ZHANG WEIYAN (CN)
WANG NING (CN)
Application Number:
PCT/CN2023/081772
Publication Date:
November 02, 2023
Filing Date:
March 16, 2023
Export Citation:
Assignee:
BEIJING CHEST HOSPITAL CAPITAL MEDICAL UNIV (CN)
BEIJING TUBERCULOSIS CHEST CANCER INST (CN)
BEIJING TUBERCULOSIS CHEST CANCER INST (CN)
International Classes:
A61K31/4409; A61K31/496; A61K31/4965; A61K45/06; A61P11/00; A61P31/06
Domestic Patent References:
| WO2017118584A1 | 2017-07-13 |
Foreign References:
| CN114732818A | 2022-07-12 | |||
| CN105902507A | 2016-08-31 | |||
| CN107019697A | 2017-08-08 | |||
| CN1857725A | 2006-11-08 |
Other References:
BATTAH BASEM, CHEMI GIULIA, BUTINI STEFANIA, CAMPIANI GIUSEPPE, BROGI SIMONE, DELOGU GIOVANNI, GEMMA SANDRA: "A Repurposing Approach for Uncovering the Anti-Tubercular Activity of FDA-Approved Drugs with Potential Multi-Targeting Profiles", MOLECULES, vol. 24, no. 23, November 2019 (2019-11-01), pages 4373, XP093103677, DOI: 10.3390/molecules24234373
WANG, JIE: "Tuberculosis Treatment and Drug Progress", PHARMACEUTICAL AND CLINICAL RESEARCH, vol. 18, no. 5, 31 October 2010 (2010-10-31)
WANG, JIE: "Tuberculosis Treatment and Drug Progress", PHARMACEUTICAL AND CLINICAL RESEARCH, vol. 18, no. 5, 31 October 2010 (2010-10-31)
Attorney, Agent or Firm:
BEIJING HUAKE UNION PATENT OFFICE (CN)
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