USE OF CHAETOCIN IN ANTI-AGING

Title:

USE OF CHAETOCIN IN ANTI-AGING

Document Type and Number:

WIPO Patent Application WO/2023/241119

Kind Code:

A1

Abstract:

Disclosed is use of chaetocin in anti-aging. The present invention adopts an aging cell model and an aging mouse model to screen and obtain a drug, chaetocin, which has the effect of anti-aging. By means of cell and mouse experiment verification, chaetocin not only can effectively inhibit alopecia, weight loss, cardiac fibrosis, liver fibrosis, renal fibrosis, spleen fibrosis, pulmonary fibrosis, adventitial fibrosis, and smooth muscle loss, but can also prolong the life span, increase abdominal fat, and alleviate cardiac inflammation, renal inflammation, liver inflammation, pulmonary inflammation, spleen inflammation, small intestine inflammation, and skin inflammation. Chaetocin provided by the present invention can be used as an anti-aging drug, and is applied to research and development of various drugs for treating aging-related diseases.

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Inventors:

ZHANG CHUANMAO (CN)
WANG XIANGYANG (CN)

Application Number:

PCT/CN2023/080299

Publication Date:

December 21, 2023

Filing Date:

March 08, 2023

Export Citation:

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Assignee:

UNIV BEIJING (CN)

International Classes:

A61K31/548; A61P17/14; A61P39/00; A61P43/00

Foreign References:

CN115364105A	2022-11-22
CN115364220A	2022-11-22
CN112656814A	2021-04-16
CN108685928A	2018-10-23
CN103356637A	2013-10-23
US20210123061A1	2021-04-29

Attorney, Agent or Firm:

CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)

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