Title:
USE OF COMBINATION OF SMALL MOLECULE COMPOUND MLN4924 AND IFNα IN RESISTING HBV
Document Type and Number:
WIPO Patent Application WO/2021/217889
Kind Code:
A1
Abstract:
Disclosed is the use of a combination of small molecule compound MLN4924 and IFNα in the preparation of anti-HBV drugs.
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Inventors:
ZHENG MIN (CN)
XIE MINGJIE (CN)
YAO JIPING (CN)
XIE MINGJIE (CN)
YAO JIPING (CN)
Application Number:
PCT/CN2020/101539
Publication Date:
November 04, 2021
Filing Date:
July 13, 2020
Export Citation:
Assignee:
UNIV ZHEJIANG (CN)
International Classes:
A61K38/21; A61K31/519; A61P31/20
Domestic Patent References:
| WO2018054891A1 | 2018-03-29 | |||
| WO2019210392A1 | 2019-11-07 |
Foreign References:
| CN103520163A | 2014-01-22 |
Other References:
SEKIBA KAZUMA, OTSUKA MOTOYUKI, OHNO MOTOKO, YAMAGAMI MARI, KISHIKAWA TAKAHIRO, SEIMIYA TAKAHIRO, SUZUKI TATSUNORI, TANAKA ERI, IS: "Pevonedistat, a Neuronal Precursor Cell-Expressed Developmentally Down-Regulated Protein 8-Activating Enzyme Inhibitor, Is a Potent Inhibitor of Hepatitis B Virus", HEPATOLOGY, vol. 69, no. 5, 31 May 2019 (2019-05-31), pages 1903 - 1915, XP055862200, ISSN: 0270-9139, DOI: 10.1002/hep.30491
XIONG FANG-WU: "Recombinant Interferon α-2b", CHINESE DICTIONARY OF CLINICAL DRUGS, CHEMICAL DRUGS, VOLUME 2, 31 August 2018 (2018-08-31)
SHI YUAN-YUAN: "Clinical comparative observation of 60 cases of chronic hepatitis B treated with long-acting interferon and conventional interferon", THE MEDICAL FORUM, vol. 19, no. 5, 28 February 2015 (2015-02-28), pages 640 - 642, XP055862201
XIONG FANG-WU: "Recombinant Interferon α-2b", CHINESE DICTIONARY OF CLINICAL DRUGS, CHEMICAL DRUGS, VOLUME 2, 31 August 2018 (2018-08-31)
SHI YUAN-YUAN: "Clinical comparative observation of 60 cases of chronic hepatitis B treated with long-acting interferon and conventional interferon", THE MEDICAL FORUM, vol. 19, no. 5, 28 February 2015 (2015-02-28), pages 640 - 642, XP055862201
Attorney, Agent or Firm:
HANGZHOU QIUSHI PATENT OFFICE CO., LTD. (CN)
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