Title:
USE OF DMSO IN THE TREATMENT OF NEURODEGENERATIVE DISEASES CAUSED BY PRIONS
Document Type and Number:
WIPO Patent Application WO2003015760
Kind Code:
A8
Abstract:
The present invention relates to a pharmaceutical composition for the treatment and/or delaying the onset of clinical symptoms and/or delaying the progress of a neurodegenerative disorder caused by prions. The composition of the invention comprises as an active ingredient DMSO, and optionally further comprising pharmaceutically acceptable additives and/or diluents. The composition of the invention is particularly applicable in the treatment of neurodegenerative disorders associated with enhanced accumulation of PrP into amyloid plaques. The invention further relates to methods of treatment of a neurodegenerative disorder caused by prions and to the use of DMSO in the preparation of a pharmaceutical composition for the treatment and/or delay of the onset of clinical symptoms and/or delay of progress of neurodegenerative disorders caused by prions.
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Inventors:
GABIZON RUTH (IL)
SHAKED GIDEON M (IL)
SHAKED GIDEON M (IL)
Application Number:
PCT/IL2002/000672
Publication Date:
September 04, 2003
Filing Date:
August 14, 2002
Export Citation:
Assignee:
HADASIT MED RES SERVICE (IL)
GABIZON RUTH (IL)
SHAKED GIDEON M (IL)
GABIZON RUTH (IL)
SHAKED GIDEON M (IL)
International Classes:
A61K31/10; A61P25/20; A61K9/08; A61P25/28; (IPC1-7): A61K31/10; A61P25/28
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