Title:
USE OF MMPI IN PREPARATION OF TRYPSIN INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2024/008204
Kind Code:
A1
Abstract:
Provided is the use of MmPI in the preparation of a trypsin inhibitor. The amino acid sequence of the MmPI is as shown in SEQ ID NO. 1. In the present invention, it is confirmed that MmPI in mulberry leaves has a trypsin inhibitory activity, and the physical and chemical properties thereof are disclosed. The MmPI has good application prospects in the preparation of the trypsin inhibitor. On the basis that the physical and chemical properties of MmPI are confirmed, the activity of the MmPI can be eliminated in a targeted manner, so that the development and utilization of mulberry leaf resources in animal feeds are promoted, new perspectives and ideas are provided for the development and utilization of mulberry leaves in animal feeds and health foods, and the economic benefits of mulberry resources are improved.
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Inventors:
LI YOUSHAN (CN)
ZHU RUI (CN)
LUO ZHUXING (CN)
ZHU RUI (CN)
LUO ZHUXING (CN)
Application Number:
PCT/CN2023/111378
Publication Date:
January 11, 2024
Filing Date:
August 07, 2023
Export Citation:
Assignee:
UNIV SHAANXI TECHNOLOGY (CN)
International Classes:
C07K14/415; C07K1/00; C07K14/81; C12N1/21; C12N15/29; C12N15/70
Foreign References:
| CN115925847A | 2023-04-07 | |||
| CN113785933A | 2021-12-14 |
Other References:
LUO ZHUXING, YANG JINHONG, ZHANG JIE, MENG GANG, LU QINGJUN, YANG XI, ZHAO PING, LI YOUSHAN: "Physicochemical Properties and Elimination of the Activity of Anti-Nutritional Serine Protease Inhibitors from Mulberry Leaves", MOLECULES, MDPI AG, CH, vol. 27, no. 6, 11 March 2022 (2022-03-11), CH , pages 1820, XP093125414, ISSN: 1420-3049, DOI: 10.3390/molecules27061820
DATABASE Protein 26 February 2018 (2018-02-26), ANONYMITY: "proteinase inhibitor [Morus notabilis]", XP093125427, retrieved from NCBI Database accession no. XP_024023749
YU-PENG WANG, LIANG JIU-BO; DING GUANG- YU;LI WEN-SHENG; YANG GUANG-WEI: "Identification and Expression Pattern Analysis of the Serine Protease Inhibitor Genes inMorus notabilis ", SCIENCE OF SERICULTURE, vol. 40, no. 4, 15 August 2014 (2014-08-15), pages 582 - 591, XP093125422, DOI: 10.13441/j.cnki.cykx.2014.04.004
陆颖 (LU, YING): "桑椹中的胰蛋白酶抑制剂及其对桑椹免疫增强作用影响的研究 (Non-official translation: Study on Trypsin Inhibitors in Mulberries and Their Effect on the Immunological Enhancement of Mulberries)", 万方平台 (WANGFANG PLATFORM), 3 November 2016 (2016-11-03)
DATABASE Protein 26 February 2018 (2018-02-26), ANONYMITY: "proteinase inhibitor [Morus notabilis]", XP093125427, retrieved from NCBI Database accession no. XP_024023749
YU-PENG WANG, LIANG JIU-BO; DING GUANG- YU;LI WEN-SHENG; YANG GUANG-WEI: "Identification and Expression Pattern Analysis of the Serine Protease Inhibitor Genes inMorus notabilis ", SCIENCE OF SERICULTURE, vol. 40, no. 4, 15 August 2014 (2014-08-15), pages 582 - 591, XP093125422, DOI: 10.13441/j.cnki.cykx.2014.04.004
陆颖 (LU, YING): "桑椹中的胰蛋白酶抑制剂及其对桑椹免疫增强作用影响的研究 (Non-official translation: Study on Trypsin Inhibitors in Mulberries and Their Effect on the Immunological Enhancement of Mulberries)", 万方平台 (WANGFANG PLATFORM), 3 November 2016 (2016-11-03)
Attorney, Agent or Firm:
XI'AN MINGZE INTELLECTUAL PROPERTY AGENCY OFFICE (GENERAL PARTNERSHIP) (CN)
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