Title:
USE OF NUCLEAR MAGNETIC RESONANCE AND NEAR INFRARED TO ANALYZE BIOLOGICAL SAMPLES
Document Type and Number:
WIPO Patent Application WO/2013/033638
Kind Code:
A3
Abstract:
In one aspect, the disclosure provides methods for using NMR and NIR to evaluate biological samples. In some embodiments, the methods include a step of performing a Nuclear Magnetic Resonance (NMR) analysis on a sample to obtain an NMR spectrum, a step of performing a Near Infrared Spectroscopy (NIR) analysis on the sample to obtain an NIR spectrum, and/or a step of performing a data fusion analysis to evaluate the NIR spectrum.
Inventors:
LANAN MAUREEN (US)
ALI AMR (US)
ALI AMR (US)
Application Number:
PCT/US2012/053528
Publication Date:
September 26, 2013
Filing Date:
August 31, 2012
Export Citation:
Assignee:
BIOGEN IDEC INC (US)
LANAN MAUREEN (US)
ALI AMR (US)
LANAN MAUREEN (US)
ALI AMR (US)
International Classes:
G06F19/00; G01N21/35; G01N24/08
Other References:
WEBB G. A. ET AL: "MAGNETIC RESONANCE IN FOOD SCIENCE: A VIEW TO THE FUTURE", 2001, THE ROYAL SOCIETY OF CHEMISTRY, article RUTLEDGE D. N. ET AL: "Interpreting Near Infrared Spectra of Solutions by Outer Product Analysis with Time Domain - NMR", pages: 179 - 192, XP008163847
VESELA A. ET AL: "Infrared spectroscopy and outer product analysis for quantification of fat, nitrogen, and moisture of cocoa powder", ANALYTICA CHIMICA ACTA, ELSEVIER, AMSTERDAM, NL, vol. 601, no. 1, 26 September 2007 (2007-09-26), pages 77 - 86, XP022274069, ISSN: 0003-2670, DOI: 10.1016/J.ACA.2007.08.039
BARROS A. S. ET AL: "Principal component transform - Outer product analysis in the PCA context", CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 93, no. 1, 15 August 2008 (2008-08-15), pages 43 - 48, XP022734039, ISSN: 0169-7439, [retrieved on 20080407], DOI: 10.1016/J.CHEMOLAB.2008.03.009
VESELA A. ET AL: "Infrared spectroscopy and outer product analysis for quantification of fat, nitrogen, and moisture of cocoa powder", ANALYTICA CHIMICA ACTA, ELSEVIER, AMSTERDAM, NL, vol. 601, no. 1, 26 September 2007 (2007-09-26), pages 77 - 86, XP022274069, ISSN: 0003-2670, DOI: 10.1016/J.ACA.2007.08.039
BARROS A. S. ET AL: "Principal component transform - Outer product analysis in the PCA context", CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 93, no. 1, 15 August 2008 (2008-08-15), pages 43 - 48, XP022734039, ISSN: 0169-7439, [retrieved on 20080407], DOI: 10.1016/J.CHEMOLAB.2008.03.009
Attorney, Agent or Firm:
WALLER, Patrick, R.H. (Greenfield & Sacks P.C.,600 Atlantic Avenu, Boston MA, US)
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