USING ALKYLMETAL REAGENTS FOR DIRECTED METALATION OF AZAAROMATICS

Title:

USING ALKYLMETAL REAGENTS FOR DIRECTED METALATION OF AZAAROMATICS

Document Type and Number:

WIPO Patent Application WO2004092125

Kind Code:

A3

Abstract:

Substituted alkylmetal reagents such as (trimethylsilylmethyl)lithium are reacted with azaaromatic compounds and/or nitrogen heterocycle compounds to produce functionalized azaaromatic compounds and functionalized nitrogen heterocycle compounds.

Inventors:

WOLTERMANN CHRISTOPHER J (US)
SUTTON DOUGLAS E (US)

Application Number:

PCT/US2004/011661

Publication Date:

April 28, 2005

Filing Date:

April 07, 2004

Export Citation:

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Assignee:

FMC CORP (US)
WOLTERMANN CHRISTOPHER J (US)
SUTTON DOUGLAS E (US)

International Classes:

C07D213/84; C07D217/02; C07D219/00; C07D253/00; C07F1/02; C07D; (IPC1-7): C07D213/84; C07D217/02; C07D219/00; C07D253/00

Foreign References:

US6657093B2

2003-12-02

Other References:

COMINS D.L.: "Lithiation of methoxypyridines directed by alpha-amino alkoxides", J. ORG. CHEM., vol. 55, no. 1, 1990, pages 69 - 73, XP000983657
See also references of EP 1611102A4

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