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Title:
VANIN-1 INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2023/112440
Kind Code:
A1
Abstract:
This Vanin-1 inhibitor includes, as an active ingredient, a pantotheine ketone derivative represented by general formula (I) (in which X, Y, Y', Z, and Z' independently represent a hydrogen atom, a fluorine group, or a substituent substituted with a fluorine group, at least one of X, Y, Y', Z, and Z' representing a fluorine group or a substituent substituted with a fluorine group).

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Inventors:
HOSOHATA KEIKO (JP)
TAKAI SHINJI (JP)
YONEYAMA HIROKI (JP)
JIN DENAN (JP)
USAMI YOSHIHIDE (JP)
Application Number:
PCT/JP2022/037384
Publication Date:
June 22, 2023
Filing Date:
October 06, 2022
Export Citation:
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Assignee:
EDUCATIONAL FOUNDATION OF OSAKA MEDICAL AND PHARMACEUTICAL UNIV (JP)
International Classes:
A61K31/165; A61P9/00
Domestic Patent References:
WO2011152720A12011-12-08
Foreign References:
JP2015535832A2015-12-17
US20180364233A12018-12-20
Other References:
JANSEN PATRICK A. M., VAN DIEPEN JANNA A., RITZEN BAS, ZEEUWEN PATRICK L. J. M., CACCIATORE IVANA, CORNACCHIA CATIA, VAN VLIJMEN-W: "Discovery of Small Molecule Vanin Inhibitors: New Tools To Study Metabolism and Disease", ACS CHEMICAL BIOLOGY, vol. 8, no. 3, 15 March 2013 (2013-03-15), pages 530 - 534, XP093071535, ISSN: 1554-8929, DOI: 10.1021/cb3006424
Attorney, Agent or Firm:
ISEKI Katsumori et al. (JP)
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