Title:
A freeze-drying process for an ADC
Document Type and Number:
WIPO Patent Application WO/2023/185907
Kind Code:
A1
Abstract:
Provided is a freeze-drying process for an antibody drug conjungate, wherein the ADC is GQ1001. Due to the use of the present freeze-drying process parameters, especially the suitable pre-freezing cooling rate and a suitable drying vacuum, the product obtained by the process has many advantages in physical and chemical properties.
Inventors:
QIN GANG (CN)
GUO BIAN (CN)
LI XUESONG (CN)
SHI LILI (CN)
LV CAO (CN)
GUO BIAN (CN)
LI XUESONG (CN)
SHI LILI (CN)
LV CAO (CN)
Application Number:
PCT/CN2023/084611
Publication Date:
October 05, 2023
Filing Date:
March 29, 2023
Export Citation:
Assignee:
GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN)
International Classes:
A61K47/68; A61K9/19; A61K47/12; A61K47/26
Foreign References:
| US20170112944A1 | 2017-04-27 | |||
| CN107847449A | 2018-03-27 | |||
| CN110960490A | 2020-04-07 | |||
| US20200129633A1 | 2020-04-30 |
Other References:
JIN LI; LIU CHUN-HONG; HAN JUN; WANG QING-PENG; ZHANG NING; ZHANG RUI-YAN: "The Research Progress of Freeze-Drying Technology and Lyophilized Antibody Drugs.", JOURNAL OF LIAOCHENG UNIVERSITY(NAT.SCI.), vol. 32, no. 5, 31 October 2019 (2019-10-31), pages 80 - 87, XP009549285
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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