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WO/2001/074742A2 |
The invention relates to a method for oxidizing substrates such as hydrocarbons, waxes or soot. The method involves the use of a compound of formula (I) in which: R?1¿ and R?2¿ represent H, an aliphatic or aromatic alkoxy radical, carb...
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WO/2001/068576A1 |
The present invention relates to novel monocyclic and bicyclic monoterpene diols that stimulate melanogenesis in mammalian skin, hair, wool or fur, and, are useful for treating or preventing various skin and proliferative disorders, neur...
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WO/2001/058588A1 |
Ferrocene anchored chiral ligands and metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The metal complexes according to the present invention are useful as catalysts in asymmetric reactions, such...
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WO/2001/051434A1 |
The invention relates to a novel method for carrying out reactions of carbonyl compounds with organometallic reagents, especially grignard reagents. The inventive method is characterised in that the organometallic reagent and the carbony...
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WO/2001/049649A1 |
The invention relates to a process for the enantioselective preparation of tolterodine and analogues and salts thereof comprising the steps of: a) enantioselectively reducing the carbonyl function in a compound of formula (II), wherein R...
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WO/2001/044153A1 |
The invention relates to a method for producing a mixture of alcohols/ketones by decomposing an alkyl hydroperoxide, particularly to a method for producing a cyclohexanol/cyclohexanone by decomposing cyclohexyl hydroperoxide in the prese...
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WO/2001/042251A1 |
The invention relates to precursors of the A-ring of vitamin D, of formula (I): in which A, R, R¿1? and R¿2? are as defined in the specification. The invention also relates to a method of preparing compounds (I) comprising the enzymati...
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WO/2001/030730A1 |
The invention relates to a method for producing at least one alcohol by (i) hydrating at least one alkene to form the at least one alcohol, in the presence of water, by bringing said alkene(s) into contact with at least one catalyst. The...
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WO/2001/028971A1 |
The present invention relates to a process for preparing a chiral ester expressed in formula (100) by mixing and reacting: a ketone of formula (4); a ruthenium complex selected from the group consisting of compounds (1, 2 and 3) expresse...
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WO/2001/018003A1 |
A six membered, at least partially unsaturated, carbocyclic nucleoside compound, including the (-) enantiomer, the (+) enantiomer, and pharmaceutically acceptable salts and esters thereof, the compounds represented by general formula (I)...
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WO/2001/016060A1 |
A method of converting Compound A (1,3-dehydro-cyclopenta[1]phenanthren-2-one) to Compound C (1H-cyclopenta[1]phenanthren) in situ in a single reactor is disclosed.
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WO/2001/010885A2 |
The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecano...
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WO/2000/075121A2 |
This invention provides a process to prepare 10,11-(optionally substituted)methanodibenzosuberane derivatives. The invention also provides an intermediate in this process.
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WO/2000/069777A1 |
In a method of performing a chemical reaction using a Lewis acid, after the reaction is complete, the Lewis acid is extracted from the reaction product in the form of an aqueous solution, followed by drying of the aqueous solution of the...
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WO/2000/066522A1 |
The present invention provides non-steroidal compounds of formula (I) which are selective modulators (i.e., agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides p...
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WO/2000/064848A1 |
The invention relates to a method for the dihydroxylation of olefins using transition-metal catalysts for producing monofunctional, bifunctional and/or polyfunctional 1,2 diols of the formula (I): R?1¿R?2¿C(OH)-C(OH)R?3¿R?4¿. Accordi...
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WO/2000/064844A1 |
The invention relates to a method for the asymmetric dihydroxylation of olefins, using osmium catalysts for producing monofunctional, bifunctional and/or polyfunctional chiral 1,2 diols of formula (I): R?1¿R?2¿C(OH)-C(OH)R?3¿R?4¿. Ac...
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WO/2000/053550A1 |
An improved process for decomposing alkyl or aromatic hxdroperoxides to form a decomposition reaction mixture containing the corresponding alcohol and ketone. The improvement relates to decomposing the hydroperoxide by contacting the hyd...
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WO/2000/047541A1 |
Hydroxymethyl-containing alicyclic compounds represented by formula (1) or (2), wherein rings A, B, C, D, and E each represents a nonaromatic carbon ring; R?a¿ and R?b¿ each represents hydrogen or a hydrocarbon group and at least one o...
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WO/2000/044368A1 |
The present invention relates to novel monocyclic and bicyclic monoterpene diols that stimulate melanogenesis in mammalian skin, hair, wool or fur, and are useful for treating or preventing various skin and proliferative disorders, neuro...
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WO/2000/035845A1 |
Alcohols are prepared practically advantageously through hydrogenation of carbonyl compounds under mild conditions either by reacting a carbonyl compound with hydrogen in the presence of a bipyridyl derivative, a Group VIII transition me...
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WO/2000/032615A1 |
The synthesis of carbohydrates using $i(chiro)-inositol as a starting material is described, and especially to the synthesis of $i(chiro)-inositol containing IPG mimetics such as compound C4 ($i(chiro)-inositol containing oligosaccharide...
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WO/2000/030623A2 |
The present invention relates to an agent which lowers prolactin and which comprises at least one bicyclic diterpene of the labdan or cleordan type (I), (II), (III), (IV), whereby R1 is H, C¿1?-C¿3?-alkyl or C¿1?-C¿3?-acyl.
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WO/2000/027907A1 |
Grapefruit extract and nootkatone (or its analogs) and nootkatone (or its analog) derivatives are usable in volume-reduction, dissolution and reuse of styrene foams (hydrocarbon polymer plastics such as polystyrene and polypropylene), el...
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WO/2000/026165A1 |
A method of reducing an epoxidized organic compound, e.g., a C¿5-20? (un)saturated epoxy alicyclic organic compound, with hydrogen which comprises contacting the compound with hydrogen in the presence of a nickel catalyst, wherein a bas...
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WO/2000/024698A1 |
The invention relates to a method for producing alcohols and ketones from hydroperoxides by means of heterogeneous catalysis, using a catalyst that is based on zeolites with a porous structure containing at least one transition metal, wh...
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WO/2000/024725A1 |
The present invention relates to compounds which are useful in inhibiting the hepatitis C virus NS3 helicase. These compounds are useful in pharmaceutical compositions and method for treating and preventing HCV infection.
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WO/2000/017143A1 |
New active compounds are provided for the preparation of pharmaceutical compositions for medicinal use in general, and for use in dermatology, oncology, and the treatment of kidney, liver and nervous system disorders, and in which is pre...
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WO/2000/012470A1 |
An improved process for decomposing alkyl or aromatic hydroperoxides to form a decomposition reaction mixture containing the corresponding alcohol and ketone is disclosed. The improvement relates to adding water to a starting hydroperoxi...
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WO/1999/055811A1 |
The invention concerns perfumes and perfumed products comprising 4-isobutylcyclohexanols according to formula (I), wherein R¿1? represents hydrogen or a methyl or ethyl group and R¿2? represents hydrogen or a methyl group. The inventio...
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WO/1999/043646A1 |
Compounds of formula (I) wherein X is C=CH¿2? or CH¿2?; Y and Z are independently of each other hydrogen, fluorine or hydroxy; A is -C$m(Z)C-, -CH=CH- or -CH¿2?-CH¿2?-; R?1¿ and R?2¿ are independently of each other alkyl or perfluo...
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WO/1999/043645A1 |
Vitamin D derivatives having general formula (1) which are hydroxylated at the 24-position and considered as one of metabolites of physiologically active vitamin D derivatives substituted at the 2$g(b)-position wherein R¿1?, R¿2?, R¿3...
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WO/1999/041219A1 |
Acylating agents comprising: (A) a 1,2-dicarbonyl compound or its hydroxy-reduction derivative; (B) an enzyme; and (C) at least one compound selected from among (c1) metal compounds and (c2) imide compounds such as N-hydroxyphthalimide. ...
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WO/1999/040055A1 |
A catalytic process is disclosed for oxidizing cycloalkanes directly to form, in a single step, a mixture containing the corresponding alcohol and ketone. In particular, the invention relates to oxidizing a cycloalkane by contacting it w...
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WO/1999/040096A1 |
A method for the synthesis of certain N-silylated cyclopentaphenanthrene (Group IV metal) complexes is disclosed.
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WO/1999/040054A1 |
A method is disclosed for catalytically decomposing cyclododecyl hydroperoxide into cyclododecanone and cyclododecanol using a chromium catalyst.
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WO/1999/036400A1 |
A method of preparation of cholecalciferol derivatives, particularly 1$g(a),24-dihydroxycholecalciferol of formula (1), wherein substituents R¿1? and R¿2? are hydrogen, hydroxyl, or hydroxyl protecting group, R¿1? and R¿2? being the ...
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WO/1999/035119A1 |
The present invention is a method of preparing a 3-aryl-1-indanamine represented by structural formula I and physiologically acceptable salts thereof. In structure I, phenyl ring A can be unsubstituted or substituted with 1-4 substituten...
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WO/1999/032422A1 |
Isopulegol is prepared by cyclisation of citronellal using scandium trifluoromethanesulphonate as catalyst. The reaction is suitably performed at low temperature, preferably at a temperature not exceeding 15 °C.
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WO/1999/031079A2 |
The invention relates to a method for preparing an ester, by admixing a compound having structure (I or IV) with a base and an alcohol to produce an ester, wherein the alcohol is a precursor to Taxol and its analogs. The present inventio...
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WO/1999/026611A1 |
The present invention provides substituted 3,3-diphenyl indanone, indane and indole compounds, as well as analogues thereof, which are specific, potent and safe inhibitors of mammalian cell proliferation. The compounds can be used to inh...
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WO/1999/026914A1 |
Process for producing a product which has a high content of zeaxanthine, luteine or a mixture of both, such as short chain organic acid diesters of zeaxanthine, luteine or a mixture of both, usable essentially for the pigmentation of chi...
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WO/1999/024410A1 |
The invention is drawn to novel transition metal catalysts for the pratical synthesis of important chiral molecules. The transition metal catalysts comprise chiral ligands based on chiral amine oxazolinyl ligands. The invention includes ...
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WO/1999/020605A1 |
The D-homo-9,10-secocholesta-23-yne-3,25-diol derivatives of formula (I) wherein the dotted C-C bond in the D-ring is optional, C(R,R) is CH¿2? or C=CH¿2?, R?1¿ is H, F or OH, R?2¿ and R?3¿ are each independently C¿1-4?-alkyl or CF...
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WO/1999/020587A1 |
A process for simultaneously extracting, saponifying, and isolating lutein and zeaxanthin, and a mixture of several rare carotenoids in high purity from plants without the use of harmful organic solvents. Lutein crystals containing 5 % z...
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WO/1999/019419A1 |
The invention concerns trypticene derivatives corresponding to formula (I) in which the symbols have the following meanings: K?1¿, K?2¿, K?3¿, identical or different, represent moncyclic or polycyclic systems optionally containing het...
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WO/1999/016452A1 |
Novel analogs of 1$g(a), 25-dihydroxyvitamin D¿3?, which are selective agonists for the genomic responses or agonists or antagonists for the rapid cellular responses in a wide array of diseases in which 1$g(a), 25-dihydroxyvitamin D¿3?...
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WO/1999/015499A1 |
Novel 22-oxavitamin D derivatives having hydroxyl at each of the 1$g(a)- and 3$g(a)- positions and represented by general formula (I), wherein R¿1? represents linear or branched C¿4-10? alkyl having one to three hydroxyl groups; and RÂ...
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WO/1999/014174A1 |
The invention relates to substituted tetrahydronaphthaline and analogous compounds which are produced by reducing or condensing corresponding functional substituents to substituted tetrahydronaphthaline and analogous compounds according ...
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WO/1999/010304A1 |
An improved method for making cyclohexanone and cyclohexanol from oxidation of cyclohexane in which a polyprotic acid is used to neutralize caustic to prevent oligomerization of cyclohexanone during fractional distillation.
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