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WO/1999/008986A1 |
A process for the preparation of a composition having formula (5) in which a compound having formula (4) is treated with a base and a silylating agent.
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WO/1999/004902A1 |
A process for the generation of a hydration catalyst for cyclic olefins, i.e., a solid acid catalyst used in the hydration of a cyclic olefin by mixing an aqueous phase containing a solid acid catalyst with an oil phase containing a cycl...
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WO/1998/056397A1 |
A method of controlling weight in mammals by orally administering to the mammal an amount of a pharmaceutical composition containing $i(Hypericum perforatum) or active components thereof effective to control the weight of the mammal is d...
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WO/1998/055439A1 |
Indane compounds of general formulae (1) to (4) and their pharmaceutical use, particularly to achieve mast cell stabilising activity and/or anti-inflammatory activity are discribed. In these formulae R?1� to R?7� may be selected from...
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WO/1998/054193A1 |
A chiral phosphorus-based ligand, in single enantiomer form, which is capable of complexing a transition metal atom and of acting as a ligand in asymmetric chemical catalysts, which comprises the partial structure (I): R?1�R?2�P-O-C-...
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WO/1998/052894A1 |
The compound, (E)-(1R,3R)-5-[(R)-11-hydroxy-7,11-dimethyl-dodec-2-enyliden
e]-cyclohexane-1,3-diol of formula (I) is useful in the treatment or prevention of hyperproliferative skin diseases, particularly psoriasis, basal cell carcinomas...
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WO/1998/047842A1 |
The invention concerns perfumes and perfumed products comprising 3-alkylcycloalkan-1-ols of formula (I), wherein R�1? represents hydrogen or a methyl, ethyl or propyl group; R�2?, R�4? and R�5? independently represent hydrogen or...
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WO/1998/047866A2 |
24-Nor-secochola-5,7-diene derivatives of formula (I) wherein A is a single or double bond, B is a group CH�2?CH�2?, CH=CH or C$m(Z)C, T is a group CH�2? or CH�2?CH�2?, R?1� and R?3� are H or OH, C(R,R) is CH�2? or C=CHï¿...
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WO/1998/047891A1 |
Cyclic products are prepared by selective olefin metathesis of bifunctional or polyfunctional substrates in the presence of one or several homogeneous or heterogeneous metathesis catalysts in a reaction medium. The invention is character...
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WO/1998/042643A1 |
A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. ...
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WO/1998/041501A1 |
The invention provides a novel class of vitamin D related compounds, namely, the 2-alkylidene-19-nor-vitamin D derivatives, as well as a general method for their chemical synthesis. The compounds have the formula (I) where Y�1? and Yï¿...
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WO/1998/040337A1 |
An adamantane derivative having a functional group such as nitro, amino, hydroxyl, carboxyl, hydroxymethyl or isocyanato is oxidized with oxygen in the presence of an imide compound of general formula (2) (such as N-hydroxyphthalimide) o...
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WO/1998/040340A1 |
Process for decomposing a mixture containing cycloalkylhydroperoxide, which mixture includes an organic phase and an aqueous phase, wherein during the decomposition, at least one compound is present which meets the following parameters: ...
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WO/1998/034647A1 |
An arginine silicate-containing complex and its use in the prevention and treatment of atherosclerosis, as a dietary supplement and for promotion of structural integrity of bones and joints. The arginine silicate complex is synthesized b...
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WO/1998/032719A1 |
The invention relates to a method for the selective preparation of a styrene of formula (1) by reacting an acetophenone of formula (2) with hydrogen in the presence of a catalyst containing one or several oxides, in particular metal oxid...
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WO/1998/032723A1 |
3-Hydroxymethylcycloalkanols of general formula (1) useful as starting materials for polymers, and a process for producing them by reducing 3-formylcycloalkanones or 3-formylcycloalkenones. A high conversion and a high selectivity toward...
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WO/1998/030517A1 |
The invention concerns a method for reducing a carbonyl-containing compound. More precisely it concerns a method for reducing a aldehyde and/or a ketone. The reduction method which consists in reacting a carbonyl-containing compound with...
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WO/1998/023567A1 |
Improved methods for the recovery of xanthophylls from corn gluten meal are provided. More specifically, methods for the recovery of xanthophylls from corn gluten whereby relatively dry corn gluten is extracted with an organic alcohol fo...
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WO/1998/017612A1 |
The invention concerns a process for preparing oxidation products from cyclohexane by catalytic oxidation with oxygenous gases in the liquid phase. In a reaction zone the gases are brought substantially uniformly into contact with the ox...
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WO/1998/013447A1 |
The compounds of formula (I) in which R stands for a methyl or ethyl group, are used as perfume ingredients for the preparation of perfuming compositions and perfumed articles, to which they confer aromatic and thujonic notes. The compou...
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WO/1998/009931A1 |
An improved process for decomposing alkyl or aromatic hydroperoxides to form a decomposition reaction mixture containing the corresponding alcohol and ketone. The improvement relates to decomposing the hydroperoxide by contacting the hyd...
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WO/1998/005669A1 |
The present invention provides a method of synthesizing compounds of formula (I), wherein R and R' are independently (C�1?-C�4?)alkyl.
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WO/1998/003458A1 |
The present invention provides illudin analogs of general formula (I) where R�1? is (CH�2?)�n?-X-Y or H; n is 0 to 4; X is O or S or N or absent; and Y is an optionally substituted (C�1?-C�8?)alkyl, (C�6?-C�10?)aryl, (C�6...
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WO/1997/046505A1 |
In order to produce isocamphyl cyclohexanoles containing the carbon backbone of isocamphyl guaiacols or isocamphyl phenols, use is made of reduced, carrierless catalysts consisting of compressed (hydr)oxide powders of Co, Mn, Cu and poss...
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WO/1997/041096A1 |
The invention concerns new vitamin D derivatives of general formula (I) a process for their production, their use for production of medicaments, and intermediate products used in the process.
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WO/1997/030710A1 |
The present invention provides cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compounds, which may be substituted in the 1-position with amino, amido, ether or ester groups, e.g., a 1-OH cyclopentane heptanoic acid, 2-(cycloalkyl...
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WO/1997/023436A1 |
A process for forming, isolating and purifying xanthophyll crystals, preferably lutein from marigold flower petals, zeaxanthin from wolfberries or capsanthin and capsorubin from red pepper, is disclosed. A xanthophyll diester-containing ...
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WO/1997/022575A1 |
A method for preparing nootkatone, nootkatol or mixtures thereof by oxidising valencene, wherein the valencene is exposed to an oxygen atmosphere in a suitable reaction medium and in the presence of an unsaturated fatty acid hydroperoxid...
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WO/1997/020805A1 |
Indane dimer compounds of general formula 5, 6 or 9 and their pharmaceutical use, particularly to achieve smooth muscle relaxing activity and/or mast cell stabilising activity and/or antiinflammatory activity are described, wherein in fo...
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WO/1997/020806A1 |
Indane compounds of general formulas (7) and (8) and their pharmaceutical use particularly to achieve smooth muscle relaxing activity and/or mast cell stabilising activity and/or anti-inflammatory activity as described, wherein in formul...
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WO/1997/020802A1 |
Indame dimer compounds and their pharmaceutical use particularly to achieve smooth muscle relaxing activity and/or mast cell stabilising activity and/or anti-inflammatory activity are described.
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WO/1997/019058A1 |
The invention relates to a compound of formula (I) wherein A is a carbon-carbon double bond having the E or Z stereochemical configuration, or A is a carbon-carbon triple bond, Et is ethyl, and R is hydroxy and R1 is hydrogen or =CH2, or...
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WO/1997/018035A1 |
Selective oxidation process for organic substrates by contacting said substrates with an oxidant selected amongst hydroperoxides and/or hydrogen peroxide in the presence of a catalyst containing a metal complex of a least one multicoordi...
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WO/1997/017313A1 |
The invention relates to a process for the preparation of polyalcohols comprising the following stages: (a) reaction of an alcanal or ketone with formaldehyde in an aqueous solution in the presence of a tertiary amine; (b) separation of ...
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WO/1997/016423A1 |
The invention relates to a compound of formula (I) wherein A is a carbon double bond having the stereochemical configuration E or Z, i.e. of formula (a) or (b), respectively, R is hydroxy and R1 is hydrogen or =CH2 or R is hydrogen or fl...
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WO/1997/008119A1 |
This invention relates to a process for preparing cyclohexanol and cyclohexanone, in particular, to a process for preparing cyclohexanol and cyclohexanone by selectively oxidizing cyclohexane with Fe/Pd catalyst in a flow of hydrogen and...
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WO/1997/005093A1 |
A cycloalkanol is prepared by cycloaddition between a diene and a vinyl ester, wherein the ester is derived from a carboxylic acid of sufficient molecular weight to enable the reaction to be carried out at atmospheric pressure while abov...
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WO/1997/000966A1 |
A process is disclosed that bioconverts indene to (1S)-amino-(2R)-indanol substantially free of any of its stereoisomers, by the action of the enzyme dioxygenase, followed by various chemical step(s), e.g., chiral specific crystallizatio...
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WO/1996/040154A1 |
Novel 1'alpha'-hydroxy vitamin D4 and novel analogues, 1,25 dihydroxy vitamin D4 and 1,24 dihydroxy vitamin D4 which are useful as active compounds of pharmaceutical compositions for the treatment of disorders of calcium metabolism and v...
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WO/1996/040607A1 |
An improved method for the recovery of xanthophylls from corn gluten is provided. More specifically, a method for the recovery of xanthophylls from corn gluten whereby relatively dry corn gluten is extracted with an organic alcohol follo...
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WO/1996/040153A1 |
Novel 1'alpha'-hydroxy vitamin D4 and novel analogues, and preferably 1,24 dihydroxy vitamin D4, which are useful as active compounds of pharmaceutical compositions for the treatment of disorders of calcium metabolism and breast and colo...
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WO/1996/037628A1 |
A process for preparing a compound of formula (3) in which R2 is -H; which comprises the steps: (i) conversion of a compound of formula (1) into a compound of formula (2) using a dioxygenase enzyme; (ii) conversion of the compound of for...
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WO/1996/030322A1 |
Tetrafluoroethylene is obtained by subjecting metal fluoride, such as sodium fluoride, calcium fluoride or silicon fluoride, to a plasma to form a gaseous mixture of metal and reactive fluorine. This gaseous mixture is then reacted with ...
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WO/1996/030320A1 |
The present invention relates to a novel process for preparing cis-4-O-protected-substituted-2-cyclopentenol derivatives comprising, (a) dissolving a 4-O-protected-2-cyclopentenone in a suitable organic solvent; and (b) treating the solu...
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WO/1996/028406A1 |
An industrial process for producing trans-2-bromoindan-1-ol at a low cost. The trans-2-bromoindan-1-ol of formula (II) can be produced by hydrolyzing 1,2-dibromoindan of general formula (I), (wherein the relative configuration of two bro...
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WO/1996/025381A1 |
The present invention relates to the synthesis of D-chiroinositol from a dialdose, comprising the steps of condensing the dialdose by an acyloin condensation reaction to form an inosose, protecting the carbon atoms at the 2, 3, 4 and 5 p...
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WO/1996/021656A1 |
Compounds of formula (I) are useful for treating or preventing obesity, breast cancer, osteoporosis, endometriosis, cardiovascular disease and prostatic disease.
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WO/1996/017816A1 |
Novel processes for the preparation of lactam- and lactone-containing macrocycles are provided. In preferred embodiments, rapamycin and demethoxyrapamycin are prepared by a convergent synthesis regime. Intermediates useful in the synthet...
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WO/1996/015088A1 |
A method for the preparation D-chiro-inositol (I) from kasugamycin (II), comprising the steps of: (a) reacting kasugamycin with an acetylating agent to form a crude hexa-acetate intermediate; (b) purifying the crude intermediate to form ...
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WO/1996/014150A1 |
The invention relates to a device for bringing solids in the form of pourable pieces into contact with liquids, or solids into contact with liquids and gases, in a reactor by putting the reactands together. The reactor has a housing cont...
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