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WO/2007/120234A2 |
Disclosed is a chamber apparatus (10) for electroporating in vitro relatively large volumes of a fluid medium carrying biological cells or vesicles wherein a reservoir for carrying said cells and vesicles is variable in its volume on dem...
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WO/2007/116594A1 |
Disclosed is a method for forming a cell structure suitable for reconstruction of a tissue or the like, by highly versatile, inexpensive and simple manipulations without causing any serious damage to a cell. The method comprises introduc...
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WO/2007/087438A2 |
Disclosed are apparatus and methods for enhancing or improving cell cultures, including cell cultures for the production of monoclonal antibodies, using electromagnetic energy treatment, primarily using electromagnetic radiation in the n...
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WO/2007/082737A1 |
The invention relates to an operating method for a microfluidic system, comprising the following steps: feeding a carrier flow with particles (5) of a first particle type suspended therein to the microfluidic system; charging a plurality...
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WO/2007/079663A1 |
The present invention provides methods for enhancing the efficiency of cell electroporation using dielectrophoresis-assisted cell localization and uses thereof in a microfluidic biochip system. Cells are first subject to dielectrophoresi...
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WO/2007/077532A1 |
Method for making endogenous ions physiologically available in an organism, comprising the following operating steps: (a) selecting an ion species to be made physiologically available in said organism; (b) generating a variable ELF or UL...
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WO/2007/059162A2 |
Device for improving in vivo penetration of molecules into cells, comprising a generator of square unipolar electric pulses, an electrode device electrically linked to the generator, and a means (8) of injecting the active agent into the...
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WO/2007/057017A1 |
The present invention relates to the field of light induced therapy. The invention relates more particularly to a method of modulating receptor function of cells having receptor proteins, said method comprising illuminating the cells wit...
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WO/2007/058804A1 |
Dielectrophoretic (DEP) tweezers apparatus and methods for various applications, including particle trapping. Two electrodes are disposed on or otherwise constitute an elongated object forming a tip. A voltage is applied across these ele...
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WO2006083671B1 |
Disclosed are methods for activating an NKT cell, methods of stimulating an immune response in a subject, methods of improving vaccine efficacy, and methods of treating an infection. Also disclosed are methods of promoting tumor rejectio...
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WO/2007/039783A2 |
The invention provides hollow-tip-electrodes for spatially localized delivery of substances to one or more biological targets present in a population comprising target and non-target molecules, macromolecules, and/or cells. The invention...
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WO2007005180A9 |
Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.
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WO/2007/028984A1 |
An apparatus for sonoporation comprising an ultrasound source and positioning means such as an optical trap, magnetic field or electrical field for positioning one or more microbubbles at a predetermined distance (Z axis) from a surface....
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WO/2007/021994A2 |
Electrode shielding for electroporation. An apparatus includes (a) an electroporation chamber, (b) an electrode (402) in operative relation with the chamber, and (c) a conductive and water permeable barrier (404) in operative relation wi...
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WO/2007/012377A2 |
The invention relates to methods for the treatment of cells with electric fields in order to modify the membrane permeability of said cells with the aid of lipophilic ions as a medium additive. The invention more particularly relates to ...
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WO/2007/004073A2 |
An apparatus for culturing eucaryotic and/or procaryotic cells comprising an incubator (10), operating means (20) to generate predetermined environmental conditions within the incubator (10) , and one or more control devices (30) to cont...
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WO/2007/005306A1 |
A time varying electromagnetic force sleeve wherein the time varying electromagnetic force sleeve comprises a time varying electromagnetic force source operatively connected to an electrically conductive coil that can removably receive a...
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WO/2006/138314A1 |
The present invention relates to an improved apparatus and method for assembly for a cylindrical split-flow thin separation channel that is capable of continuously separating particles of interest from a suspension flowing through the ch...
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WO/2006/122380A1 |
The invention relates to antitumor agent on the base of BCG vaccine, the method his preparation and its application in patients diagnosed with oncological diseases. The agent according the invention is a mixture of two individual fractio...
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WO/2006/124152A2 |
Applying a strong static DC electric field to supersaturated aqueous glycine solutions resulted in the nucleation of the Y polymorph attributed to the electric-field induced orientation of the highly polar glycine molecules in large pree...
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WO/2006/097707A2 |
Compositions such as skin equivalents and methods for their manufacture. In particular, a method for modulating the tensile strength and/or elastic strength of a composition comprising living cells suspended in a 3-D support matrix, whic...
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WO/2006/091060A1 |
According to the conventional process of separating necessary cells from a cell mixture containing specific cells tagged with magnetic beads, there is a problem in that separation process is complicated when the separation efficiency is ...
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WO/2006/088154A1 |
It is intended to provide a method of selectively separating target cells whereby non-target cells are selectively removed from a mass of cells consisting of cells in different types, and a cell separation apparatus. A method of selectiv...
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WO/2006/087890A1 |
[PROBLEMS] To provide a manipulation device and a manipulation method capable of performing manipulation of microparticles which is extremely difficult for conventional manipulation devices and capable of performing migration or rotation...
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WO/2006/073671A1 |
A method of modifying tissue behavior, including cardiac tissue, comprising: determining a desired modification of tissue behavior for at least one of treatment of a disease, short or long term modification of tissue behavior, assessing ...
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WO/2006/052160A1 |
The invention relates to the food industry. The inventive method for producing yeast culture lysates is based on the treatment of yeast substrate by an acoustic field and consists in processing the yeast substrate whose concentration ran...
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WO/2006/038405A1 |
Cell treatment equipment comprises a container for containing a matter to be treated including a cell group formed by bonding magnetic beads having an antibody which can be bonded specifically to the antigen of a specific cell in the cel...
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WO/2006/025740A2 |
The invention is directed to processes and apparatuses for the production of chemical compounds, in particular fermentation products. According to the invention there is provided a process for the production of one or more chemical subst...
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WO/2006/001614A1 |
An electroporation apparatus comprising an elongated hollo member in order to provide a uniform electric field during electroporation, wherein specifically, electroporation is carried out b applying electric pulses through a couple of el...
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WO/2005/123898A1 |
A process and a device for retaining polarizable target-particles from a fluid suspension of polarizable target-particles comprising the steps of pumping that suspension into a vertical or inclined channel and applying an alternating ele...
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WO/2005/123906A1 |
[PROBLEMS] To provide a method of on a cell level, easily and efficiently increasing the amount of insulin secreted and/or produced. [MEANS FOR SOLVING PROBLEMS] There is provided a method characterized in that insulin-producing cells in...
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WO/2005/123190A1 |
A method of treating skin and/or skin conditions or disorders including chronoaging by the application of ultrasound.
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WO/2005/116203A2 |
A method and apparatus for electroporation includes placing a mixture of bacterial suspension and transforming DNA into an electroporation cuvette. The resulting sample is subjected through a current-limiting device to a complex 5 wavefo...
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WO/2005/115460A1 |
The invention provides a method of producing polypeptides from plant protein by using alternating high frequency high voltage electromagnetic field. The method comprises: making plant materials move in processing cavity, applying alterna...
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WO/2005/108566A2 |
A method for pretreating and disrupting cell structure of biomass by subjecting the biomass to high pressure, thereby disrupting the cell structure of the biomass is provided. Also provided is a device for performing the method, wherein ...
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WO/2005/102188A1 |
An apparatus and method for electromagnetic treatment of living tissues and cells comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be co...
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WO2005010139B1 |
A porous, collagen coated, ferromagnetic cell culture microcarrier, which is suitable for in vitro cell and tissue culture and which facilitates 3D multicellular construct generation. Also provided is a method for creating batches of mic...
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WO/2005/100540A1 |
A ready-to-use electroporation cuvette is provided that includes a cuvette, first and second electrodes positioned within the cuvette and electroporation competent cells frozen in a suspension solution within the cuvette, wherein the ele...
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WO/2005/095579A1 |
A process for preparing a composition comprising dried microorganisms, comprising culturing one or more species of a microorganism; admixing the cultured microorganism with one or more carriers; treating the microorganism with pulsed ele...
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WO/2005/090555A1 |
The invention provides methods for purifying one or more cells based on the level of one or more products secreted by the cells. In one embodiment, the method involves (a) contacting a plurality of cells immobilized in proximity to a cap...
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WO/2005/090547A1 |
The invention concerns a container (1) with chambers (2) which each comprise at least one pair of electrodes including a first (4) and a second electrode (5) for the application of electric voltage for generating an electric field within...
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WO/2005/087262A1 |
Provided is a chicken infectious anemia virus (CIAV) vaccine, comprising live CIAV passaged in MDCC-MSB-l (MSB-1) cells, wherein the vaccine does not cause Marek's Disease. Also provided is a CIAV vaccine comprising a CIA virus having th...
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WO/2005/083078A1 |
The present invention relates to a method, a chip, a device and a system for extraction of biological material form biological cells. The invention involves exposing the biological particles to an alternating electric field in a sample c...
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WO/2005/071057A1 |
A magnetic or electric field stimulating device not changing liquidity of the culture solution and not lowering the anchoring rate of cells even if living cells are electrically stimulated for a long time during the growth progress of th...
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WO/2005/070136A2 |
Methods and devices are described for the regulation of bone morphogenetic protein gene expression in bone cells via the application of fields generated by specific and selective electric and electromagnetic signals in the treatment of d...
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WO/2005/066342A1 |
An apparatus is provided for carrying out fusion of biological cells (10) and includes a base member (24) on which a conductive outer electrode (18) is supported and has an outer electrode radius (r2) and has an electrode height (19). A ...
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WO/2005/065267A2 |
One aspect of the present invention relates to magnetophoretic devices for cell clarification. In one embodiment, the magnetophoretic device is a counter-current device, comprising a plurality of pairs of magnets selected from the group ...
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WO/2005/063961A2 |
The subject of the invention in the field of biomedical technology is the evaluation procedure for the determination of the yield of hybrid cells - hybridomas in a cell vaccine and cell products, which consists of measurements of the are...
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WO/2005/064018A2 |
A method for preparing a nucleic acid probe is provided. The method comprises forming an activated cytosine or cytidine by a bisulfite catalyzed reaction; and covalently linking a reporter molecule to the activated cytosine or cytidine, ...
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WO/2005/063809A1 |
The present invention relates to Erythropoietin, (i.e. Haemopoietin, Haematopoietin, or erthropoietic stimulating factor) (EPO) having glycoform profiles or a glycoform close or identical to naturally occurring EPO (nEPO) as well as proc...
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