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JPWO2005026110A1 |
Useful new production of optically active R-form or S-form 2-amino-3-mercapto-2-methylpropionic acid derivative or salt thereof, which is useful as an intermediate for pharmaceuticals, etc., which can highly suppress the contamination of...
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JP2006521083A |
A nucleic acid molecule called an MR nucleic acid molecule encoding a novel MR protein derived from corynebacterium glutamicum involved in fine chemical biosynthesis, for example, methionine biosynthesis is described. The present inventi...
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JP2006232741A |
To provide a new substance having inhibitory activity on an HMG-CoA reductase and therefore capable of being expected to be clinically used as a pharmaceutical for infectious disease caused by bacteria, and to provide a method for produc...
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JP2006519615A |
A method for biotransformation of organic compounds using non-prokaryotic microalgae is disclosed. The method is useful to biotransform a chemical precursor compound, preferably a heterocyclic compound, to a chemically distinct final pro...
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JP2006204258A |
To obtain a new bacterium for producing an unusual-polyhydroxyalkanoate in high efficiency at a low cost and to provide a method for producing an unusual polyhydroxyalkanoate using the same.The bacterium having higher unusual-polyhydroxy...
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JP2006206834A |
To provide a poly(3-hydroxyalkanoic acid) having a specific side chain, a manufacturing method thereof, and a binder resin containing the same.The manufacturing method comprises using as a raw material a compound expressed by the formula...
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JP2006517796A |
Strain (A) of a microorganism which produces a 2-amino-4-alkylthio-butyric acid (I) by metabolizing a simple sugar and a thiol (II), or its salt, and has at least one gene encoding an enzyme with modified methionine synthase (MS) activit...
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JPWO2004078988A1 |
The following equations (I), (II) or (III):(In the formula, H1 is a heterocyclic group, etc., A1 is a single bond, etc., P2 is a phenyl group, etc., A2 is an alkylene group, etc., and C1 is a heteroatom-substituted cyclic hydrocarbon gro...
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JP2006509518A |
Chemoenzymatic methods have been developed for the stereoselective production of both (R) and (S) enantiomers of 3-hydroxy-3- (2-thienyl) propanenitrile. These optically pure key intermediates are produced by enzymatic separation of (±)...
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JP3754956B2 |
The invention provides polyhydroxyalkanoate having a bromo group in a unit and being thermally stable and capable of arbitrarily controlling physical properties, and a producing method thereof. According to the invention, there are provi...
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JP3748537B2 |
To provide a new PHA(polyhydroxyalkanoate) containing a 3-hydroxy- thioalkanoic acid unit having a side chain comprising a thienyl group having a high reactivity and its production method. The production method for the PHA involves a pro...
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JP3745298B2 |
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JP3689697B2 |
To provide a new polyhydroxyalkanoate given by solving problems (hardness and brittleness) in melt-processability caused by a conventional polyhydroxyalkanoate which is obtained by biosynthesis to have 3-hydroxybutyric acid as its polyme...
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JP3689700B2 |
To obtain a new polyhydroxyalkanoate (PHA) copolymer containing a structural unit having an aromatic ring and a vinyl group in a side chain and a different kind of structural unit which controls physical properties such as thermal proper...
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JP2005522218A |
The invention relates to methods for the fermentative production of sulfur-containing fine chemicals, in particular L-methionine, by using bacteria which express a nucleotide sequence coding for a methionine synthase (metH) gene.
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JP2005095069A |
To provide a method for producing a polyhydroxyalkanoate.This method for producing the polyhydroxyalkanoate containing in the polymeric molecule at least unit(s) bearing residue(s) on the side chain comprises culturing a microorganism ha...
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JPWO2002103025A1 |
Sulfated sugars represented by the following general formula are described. [A]-(6SO3-GlcNAc)-[C] -R (in the formula, (6SO3-GlcNAc) indicates a 6-sulfated N-acetylglucosamine residue, [A] indicates a hydroxyl group or a sugar residue. [C...
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JP2005052139A |
To provide a process for producing fractionated products from a mustard seed stock by fractionating and collecting ally isothiocyanate and p-hydroxybenzyl isothiocyanate from yellow mustard seeds or oriental mustard seeds.The mustard see...
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JP3592306B2 |
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JP2004530405A |
Provided is a method of resolving a racemic mixture of a compound of formula I to obtain a desired enantiomer: wherein Ar is C6 or C10 aromatic group that can be substituted with H, C1 to C6 alkyl, trifluoromethyl or halo, R5 is halo or ...
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JP2004520008A |
The present invention relates to compounds made by a subset of modules from one or more polyketide synthase ("PKS") genes that are used as starting material in the chemical synthesis of novel molecules, particularly naturally occurring p...
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JP2004059506A |
To provide a saccharide compound achieving regulation or the like of a bond between each of L-selectin, P-selectin and chemokine, and its ligand; and to provide a treating and preventing agent for ameliorating a symptom of a disease such...
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JP2004501619A |
A process for the preparation of biologically active compounds, wherein active substances having additional functional groups and a modified spectrum of activity and modified application properties are obtainable from medicinal substance...
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JP2003319792A |
To provide a method for controlling the molecular weight of a polyhydroxyalkanoate in which units containing phenyl, thienyl or cyclohexyl structure-having residues in side chains are contained, and to provide the polyhydroxyalkanoate ha...
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JP2003310292A |
To provide a method for efficiently producing a polyhydroxyalkanoate the monomer unit of which has an aromatic-substituted group.This method for producing the polyhydroxyalkanoate comprises using bacteria, wherein at least one kind of co...
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JP3411463B2 |
To obtain a cosmetic composition containing a neuropeptide Y (NPY)- antagonist component and capable of adjusting lipolysis/lipid biosynthesis in skin without deteriorating the natural functions of the skin. This composition contains a N...
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JP2003512073A |
Recombinant Escherichia coli host cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase from Propionibacterium shermanii or Streptomyces cinnamonensis as well as Propionibacterium sherma...
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JP2003504034A |
(57) [Summary] Saturated aliphatic carboxylic acid esters and / or correspondence by the use of short chain carboxylic acids and long chain alcohols and the complete or partial removal of water produced and / or added during the reaction...
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JP3330305B2 |
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JP3301489B2 |
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JP2001122846A |
To isolate a new compound having a specific inhibitory activity against a sphyngosine kinase. This sphyngosine kinase inhibitor is a compound expressed by formula 1 or its pharmacologically permissible salt.
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JP2001086996A |
To provide a method for producing natural aromatic, aliphatic and thio-carboxylic acids by fermentation, which is a biological method for producing various kinds of carboxylic acids by an enzymic oxidation of corresponding alcohols by us...
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JP3142627B2 |
PURPOSE: To stereoisomerically enrich 2-amino-3-hydroxy-3-phenylpropionic acid by using D-threonine aldolase. CONSTITUTION: A mixture of enantiomeric D,L-threo 2-amino-3-hydroxy-3- phenylpropionic acids can be stereoisomerically enriched...
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JP3120684B2 |
PURPOSE: To obtain the subject new mutant enzyme obtained by a genetic engineering technique using a mutant gene originated from Bacillus stearothermophilus and effective for the synthesis of geranylgeranyl diphosphate playing a role in ...
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JP3093056B2 |
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JP2000253891A |
To efficiently obtain an optically active alcohol of high purity that is useful as an intermediate for medicines and agrochemicals in a high yield by reacting a reductase with a specific alkyl vinyl sulfide to form an optically active di...
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JP2000508535A |
Immobilized garlic alliinase wherein the alliinase is chemically, physically or biologically immobilized, is useful in a method for continuous production of allicin. The method comprises adding a solution of alliin as substrate to a colu...
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JPH11341987A |
To obtain a new gene which has a specific amino acid sequence, converts dibenzothiophenesulfonic acid to 2-(2'-hydroxyphenyl)benzenesulfinic acid, and can be used, for example, for producing an enzyme capable of easily releasing sulfur i...
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JP2979671B2 |
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JPH11206395A |
To produce the subject new derivative comprising a specific phthalaldenyde derivative, capable of suppressing glucose-6-phosphate translocase and useful for producing a prophylactic and therapeutic agent, etc., for glucose dysmetabolism ...
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JPH11196889A |
To obtain the subject compound useful for medicines, agrochemicals and chemical materials industrially advantageously by effecting a microorganism having a function of stereoselectively hydrogenating a carbon-carbon double bond of a 2-, ...
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JP2875308B2 |
An Allium genus plant, typically garlic is extracted by adding water or alcohol to the garlic, subjecting a mixture of the solvent and the garlic to extraction, and collecting an extract liquid. A composition containing S-allylcysteine i...
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JPH1175885A |
To provide a method for readily producing calcium 2-hydroxy-4- methylthiobutanoate without bi-producing polycalcium-2-hydroxy-4- methylthiobutanoates in high yield by a method not inducing a problem of treating an inorganic salt waste. T...
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JPH11503021A |
A process is described for the dimerization of a substituted aromatic compound of the formula (I): NHR where R is H, an alkyl group or an aryl group; R1 and R2 represent an alkyl group, an aryl group, an alkenyl group, an alkynyl group, ...
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JPH119293A |
To obtain a new strain belonging to the genus Rhodococcus erythropolis, having the ability to efficiently degrade hard-to-decompose alkylated benzothiophenes and alkylated dibenzothiophenes, and useful for e.g. the desulfurization of fos...
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JPH11500303A |
A process for producing sulphoxide enriched in the (R) or the (S) enantiomer as required comprises contacting a racemic mixture of such sulphoxide with the enzyme DMSO reductase derived from a bacterium selected according to the enantiom...
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JPH10507631A |
PCT No. PCT/FR95/01196 Sec. 371 Date Mar. 20, 1997 Sec. 102(e) Date Mar. 20, 1997 PCT Filed Sep. 19, 1995 PCT Pub. No. WO96/09403 PCT Pub. Date Mar. 28, 1996A method for the enzymatic hydrolysis of racemic alpha -substituted 4-methylthio...
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JPH10179183A |
To obtain a carboxylic acid without producing by-products such as ammonium hydrogensulfite. This method for producing carboxylic acid comprises (1) a carboxylic acid salt-producing process comprising (a) producing at least corresponding ...
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JP2769194B2 |
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JPH10168054A |
To obtain the subject new substance with excellent anti-tumor action, useful in the medical and pharmaceutical fields by innoculating a BE-41926 producing bacterium strain in a medium containing nutritional sources and culturing it aerob...
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