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Patent Searching and Data


Title:
PRODUCTION OF OPTICALLY ACTIVE 2-, 3-DISUBSTITUTED PROPIONIC ACID DERIVATIVE
Document Type and Number:
Japanese Patent JPH11196889
Kind Code:
A
Abstract:

To obtain the subject compound useful for medicines, agrochemicals and chemical materials industrially advantageously by effecting a microorganism having a function of stereoselectively hydrogenating a carbon-carbon double bond of a 2-, 3-disubstituted acrylic acid derivative.

This method for producing an optically active 2-, 3-disubstituted propionic acid derivative expressed by formula II efficiently at a low cost comprises effecting microbes of a microorganism having a function of stereo selectively hydrogenating a carbon-carbon double bond of a 2-, 3-disubstituted acrylic acid derivative expressed by formula I [R1 is a (substituted) alkyl, a (substituted) carboxyl, hydroxyl, a lower alkyloxy, a (substituted) aryl, a (substituted) heterocyclic ring group; R2 is H or a 1-6C lower alkyl; X is nitro, cyano, a lower alkyloxy, a (substituted) thiol, a (substituted) sulfonic acid or a (substituted) amino]. The compound is useful as various medicines, agrochemicals and chemicals, or their synthetic intermediates, or the like.


Inventors:
YAMAGISHI MASAHIRO
UEDA MAKOTO
Application Number:
JP1998000008215
Publication Date:
July 27, 1999
Filing Date:
January 20, 1998
Export Citation:
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Assignee:
MITSUBISHI CHEM CORP
International Classes:
C12P7/62; C12P11/00; C12P13/00; C12P17/00; C12R1/645; C12R1/72; C12R1/84; (IPC1-7): C12P7/62; C12P11/00; C12P13/00; C12P17/00
Attorney, Agent or Firm:
長谷川 曉司