Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 1 - 50 out of 167,255

Document Document Title
WO/2018/129535A1
Provided herein are methods and kits for determining the presence or absence of certain microRNA biomarkers in a blood sample of a female patient. The microRNA biomarkers are associated with ovarian cancer. Also provided are methods for ...  
WO/2018/129226A1
Exemplary embodiments of the present disclosure can include, for example, an atomic force microscopy (AFM) system, including a cantilever(s), an optical pickup unit(s) (OPU(s)) including a laser positioned over the cantilever(s), and a p...  
WO/2018/126696A1
A gene sequence detection chip, a gene sequence detection device and a gene sequence detection method. The gene sequence detection chip comprises : a substrate (1); an electrode (7) located above the substrate (1); a signal lead (8), whi...  
WO/2018/129368A2
The present disclosure relates to methods of analyzing activity of nucleases.  
WO/2018/129293A1
The invention provides a kit for detecting the presence or absence of mutations in the selected regions of the target genes associated with colorectal cancer, comprising XNA clamps and primers; wherein the XNA clamps are capable of hybri...  
WO/2018/129328A1
Compositions and methods for optically-verified, sequence-controlled polymer synthesis are described.  
WO/2018/127386A1
The invention relates to a nucleic acid-based lateral flow assay (LFNA) strip for detecting an analyte nucleic acid molecule in a sample (100), wherein the detection of the analyte is based on the detection of a marker (203) after the mi...  
WO/2018/129078A1
The disclosure provides methods and compositions that are useful to lessen and/or cure bacterial biofilms and treat diseases or disorders associated with biofilms using one or more novel polypeptide vaccines, antibodies, antibody fragmen...  
WO/2018/127853A1
Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of an antibiotic needed to inactivate bacteria (Minimum Inhibitory Concentration...  
WO/2018/129528A1
Embodiments of the present disclosure relate generally to the treatment and prevention of ischemic injury. More particularly, embodiments of the present disclosure include materials and methods for treating and preventing ischemic injury...  
WO/2018/129497A1
The present invention generally relates to a method of diagnosing, prognosing and treating prostate cancer patients. Particularly, the present invention relates to a method of selecting patients with castration resistant prostate cancer ...  
WO/2018/129333A1
The present invention generally relates to systems and methods for determining molecular motion, for example, using nanostructures such as DNA origami structures. In certain embodiments, a nanostructure, such as a DNA origami structure, ...  
WO/2018/127674A1
The invention relates in particular to a method for detecting and/or quantifying cell-free DNA from a sample of biological fluid of a patient of interest, comprising at least: (i) a step of extracting cell-free DNA from a sample of biolo...  
WO/2018/128974A1
A method includes fluorescence imaging a cell that synthesizes Type 1 collagen. The cell includes a first gene encoding collagen a1(I) tagged with a first fluorescent tag and a second gene encoding collagen a2(I) tagged with a second flu...  
WO/2018/128286A1
The present invention relates to a method for rapidly detecting a target nucleic acid and a method for rapidly diagnosing a disease using said method, the method for rapidly detecting a target nucleic acid comprising the steps of: (a) by...  
WO/2018/127408A1
A target DNA sequence (1 ) is contacted with ML+MR ligation oligonucleotides (10, 20) under hybridization conditions. The ligation oligonucleotides (10, 20) comprises a respective UMI (14, 15). A ligating agent ligates together the ligat...  
WO/2018/128080A1
With an objective of simply evaluating the quality of cells, this cell observation system is provided with: a cultivation observation device (3) for acquiring, over time, images of the inside of a cultivation container (C) for cultivatin...  
WO/2018/127545A1
Dislcosed are immunogenic proteins from Pseudomonas aeruginosa as well as nucleic acids, vectors and transformd cells useful for expression of the proteins. Also disclosed are methods for prophylaxis of infection with Pseudomonas aerugin...  
WO/2018/127786A1
The present invention relates to compositions, systems, and methods for determining a treatment course of action. In particular, the present invention relates to compositions, systems, and methods for utilizing gene expression profiles t...  
WO/2018/129314A1
Memory efficient methods determine corrected color values from image data acquired by a nucleic acid sequencer during a base calling cycle. Such methods may: (a) obtain an image of a substrate (e.g., a portion of a flow cell) including a...  
WO/2018/127643A1
The present invention concerns a method for measuring the effectiveness of a disinfection device, said measurement method comprising: - a step (E2) of contaminating at least one test sample and at least one control sample with a microbio...  
WO/2018/129120A1
The current disclosure provides a method that can specifically label and directly amplify 5hmC site on genomic DNA without pull-down or bisulfite treatment, which enables one to map the 5hmC site from a single DNA molecule. Aspects of th...  
WO/2018/128013A1
Provided are a novel PCR measurement method and measurement device. One mode of this invention is a DNA detection method for detecting DNA in a droplet including DNA and a fluorescent marker probe that hybridizes with the DNA, in oil. Th...  
WO/2018/128544A1
The invention relates to a method for typing a sample of a cancer patient for an activated or non-activated TGF beta signaling pathway, comprising the steps of providing a sample from a cancer patient, whereby the sample comprises gene e...  
WO/2018/128516A1
The present invention relates to: a method for providing information for the prediction or diagnosis of oral precancer or oral cancer characterized by confirming expression of the Axin2 gene or the snail gene in an oral leukoplakia tissu...  
WO/2018/126584A1
Provided is a circular transposon complex. The circular transposon complex comprises a Tn5 transposase and an insert DNA. The insert DNA comprises a transposon terminal sequence, two tag sequences, and a DNA sequence containing an enzyme...  
WO/2018/129214A1
The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorpor...  
WO/2018/129043A1
Compositions, kits and methods for diagnosing and treating an increased risk of preterm birth (PTB) involves a composition comprising at least one reagent capable of detecting, binding, specifically complexing with, or measuring the leve...  
WO/2018/128777A1
An example method includes reacting a first solution and a different, second solution on a flow cell by flowing the first solution over amplification sites on the flow cell and subsequently flowing the second solution over the amplificat...  
WO/2018/129402A1
Disclosed are methods of treating colorectal cancer that involve administering a composition comprising an effective amount of miR-451a to cells in the colorectal cancer and further treating the colorectal cancer cells with ionizing radi...  
WO/2018/129529A1
Compositions and methods for diagnosing and treating asthma and asthma patients a Th2 high asthma phenotype are disclosed.  
WO/2018/121468A1
Provided are a method and a device for detecting a genetic mutation, and a kit for typing genotypes of a pregnant woman and a fetus. The method comprises: performing high-throughput sequencing on free DNA in a pregnant woman's peripheral...  
WO/2018/121634A1
Provided are a method and a kit for nonspecific replication of a DNA fragment. The method comprises adding an adaptor to a desired DNA fragment for replication to obtain an adaptor-added DNA fragment; performing PCR amplification on the ...  
WO/2018/124293A1
The present invention provides a novel method for the classification of adjuvants. In one embodiment, the present invention provides a method for generating organ transcriptome profiles for adjuvants, said method comprising: (A) a step f...  
WO/2018/126036A1
Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, inc...  
WO/2018/124003A1
This method detects the presence or absence of functional gastrointestinal disorder by measuring bacterial occupancy within the human stomach.  
WO/2018/124210A1
The present disclosure provides a ring-shaped cardiac muscle cell mass in which an electric signal or a calcium signal can progress while circulating therethrough. Also provided is a method for producing the ring-shaped cardiac muscle ce...  
WO/2018/124744A1
The present invention relates to a method for diagnosing a liver disease, such as liver cancer and cirrhosis, via bacterial metagenomic analysis and, more particularly, to a method for diagnosing liver cancer and cirrhosis by performing ...  
WO/2018/124640A1
A substance inhibiting the expression of the CCND3 or PAK2 gene, the substance containing a nucleotide such as miR-4779, may be efficiently used for preventing or treating cancer. In addition, the substance inhibiting the expression of t...  
WO/2018/125982A1
The invention relates to a system and methods for enhancing access to nuclear informational molecules, such as DNA, RNA, and proteins, by analytical biomolecules, such as transposome complexes, by treating nuclei with a nuclear permeabil...  
WO/2018/124619A1
The present invention relates to a method for diagnosing bladder cancer via microbial metagenomic analysis and, more particularly, to a method for diagnosing bladder cancer by performing metagenomic analysis of a microbe, such as a bacte...  
WO/2018/124742A1
The present invention relates to a method for diagnosing a prostatic disease, such as prostate cancer and prostatic hypertrophy, via bacterial metagenomic analysis and, more particularly, to a method for diagnosing prostate cancer and pr...  
WO/2018/124119A1
The present invention provides a detection method for chromosomal abnormalities, the detection method being characterized by including: a step for adding an anti-CD3 antibody to T lymphocytes derived from human pluripotent stem cells and...  
WO/2018/123764A1
Provided is a combination of gene markers, which enables the highly sensitive detection of a remaining very small lesion of neuroblastoma even in a sample in which the amounts of genes expressed are small. A reagent according to the pres...  
WO/2018/125913A1
Glucose-sensing luminescent dyes, polymers, and sensors are provided. Additionally, systems including the sensors and methods of using these sensors and systems are provided.  
WO/2018/124617A1
The present invention relates to a method for diagnosing lung cancer via bacterial metagenomic analysis and, more particularly, to a method for diagnosing lung cancer by performing bacterial metagenomic analysis using a subject-derived s...  
WO/2018/126192A1
The instant disclosure provides methods and compositions related to discovery of MAP2K1 (MEK1) as a therapeutic target for treatment or prevention of arteriovenous malformations (AVMs). Therapeutic and/or prophylactic uses and compositio...  
WO/2018/124606A1
The present invention relates to a method for diagnosing breast cancer via bacterial and archaeal metagenomic analysis and, more particularly, to a method for diagnosing breast cancer by performing bacterial and archaeal metagenomic anal...  
WO/2018/124665A1
The present invention relates to a method for amplifying at least three target nucleic acid molecules with reduced primer dimer formation in a multiplex amplification reaction. The method of present invention can inhibit primer dimer for...  
WO/2018/124189A1
The purpose of the present invention is to provide a method of selecting cell lines in which the reduction of a recombinant protein has been suppressed. The present invention pertains to a method of selecting cells, said method comprisin...  

Matches 1 - 50 out of 167,255