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WO/2013/070807 |
The disclosure provides methods for determining the self-renewal potential of a cancer stem cell (CSC), or for predicting the drugability (susceptibility to a drug) of a CSC, and/or for predicting the progression of a cancer that corresp...
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WO/2013/068572 |
The invention prov ides an enzymatic method for measuring the concentration of one or more analytes in the plasma portion of a blood derived sample, containing a first and a second component, where said second component interferes with t...
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WO/2013/071233 |
The invention provides methods for detecting infectious agents in a sample. The invention further provides a novel virus, immunogenic and vaccine compositions comprising the novel virus, and methods of using such compositions for the tre...
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WO/2013/068685 |
The present invention relates to a method for studying a sample containing a bacterial population of Staphylococcus aureus using a specific mass spectrometry technique which enables the specific detection, on the mass spectrum obtained, ...
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WO/2013/070060 |
The present invention discloses a system which consists of 4 pairs of primers that specifically detect Salmonella spp., S. Typhi and S. Paratyphi A with an internal control. The system, when applied in polymerase chain reaction (PCR) und...
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WO/2013/068422 |
The present invention concerns a method for comparing, in at least two samples A 1 and A 2 , the amount of RNA of a target gene t, wherein a fixed amount of external control sample C is added during RNA extraction of samples A 1 and A 2 ...
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WO/2013/071142 |
Disclosed are markers associated with sensitivity to treatment with proteasome inhibitors. Sensitivity is observed when RAS gene is wild type in tumor cells. Compositions and methods are further provided to assess markers of marker genes...
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WO/2013/069452 |
A method for observing stem cells with an observation device (1) is provided with: a step for disposing stem cells (C) in a dish (11); a step for loading the dish (11) onto a waveguide (21) via water (13); a step for inputting illuminati...
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WO/2013/068445 |
The inventors have found that the ABHD11 protein (alias Abhydrolase domain-containing protein 11, PP1226, WBSCR21, Williams-Beuren syndrome chromosomal region 21 protein) exhibits diacylglycerol lipase activity provided the N-terminal mi...
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WO/2013/068103 |
Six new mutations were found in exon 19 of the EGFR gene, the exon that is often mutated in tumors. The invention comprises methods of detecting the mutations, methods of prognosis and methods of predicting response to treatment based on...
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WO/2013/068486 |
The invention relates to the diagnosis and the treatment of male infertility, in particular to the involvement of the miRNA 29 family in male infertility.
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WO/2013/071159 |
Although metabolic networks have been reconstructed on a genome-scale, the corresponding reconstruction and integration of governing transcriptional regulatory networks has not been fully achieved. Here such an integrated network was con...
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WO/2013/071168 |
In a first aspect, there is provided an isolated polypeptide substrate for a disintegrin-like and metallopeptidase with thrombospondin type-1 motif, 13 (ADAMTS13) that is from 45 to 70 amino acids in length and has an amino acid sequence...
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WO/2013/070763 |
Disclosed herein is a nanoconstruct comprising an aptamer and a gold nanostar. The nanoconstruct can be used in a method of inducing changes to a nuclear phenotype of a cell comprising transporting the nanoconstruct to a nucleus of a cel...
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WO/2013/069732 |
The present invention provides a method for manufacturing small objects that includes using microstructures formed of organic matter as a mold, placing the mold on a circuit board, depositing the desired element on the surface of an orga...
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WO/2013/070984 |
The present embodiments provide systems and methods for determining gene signatures relating to MS and specifically interferon-based treatments including gene/differential gene expression database for providing a gene predictor set; a bi...
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WO/2013/068654 |
The present invention provides a method for detecting the presence of microcystin-producing toxic cyanobacteria in a sample comprising the step of contacting nucleic acid obtained from an environmental sample with primers specifically hy...
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WO/2013/070893 |
A method for indentifying test agents that exhibit prebiotic activity on human skin commensal microorganisms and cosmetic compositions that include such agents. The method includes providing a test culture of a test agent, a human skin c...
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WO/2013/068730 |
The present invention relates to a method of determining platelet activity. The present invention also relates to a method of monitoring the efficacy of an anti-platelet therapy, a method of predicting and/or diagnosing a platelet-relate...
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WO/2013/070950 |
The present invention teaches methods and systems for diagnosing ovarian cancer in a subject, or the recurrence thereof, using the novel marker IFFO1-M. The invention further teaches that this marker can be used in conjunction with addit...
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WO/2013/071231 |
The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels.
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WO/2013/071163 |
Disclosed herein are markers associated with sensitivity to treatment with proteasome inhibitors. Sensitivity is observed when RAS gene is wild type in tumor cells. Compositions and methods are provided to assess markers of marker genes ...
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WO/2013/069645 |
The purpose of the present invention is to provide: a method for measuring ethanolamine phosphate in a sample in a simple manner; and a regent, a kit, a program and others for use in the method. A method for measuring ethanolamine phosph...
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WO/2013/070079 |
The blood-brain barrier (BBB) separates the blood and the central nervous system (CNS). Here it is disclosed that blood-brain barrier function can be increased with particular nucleic acid sequences, in particular in patients suffering f...
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WO/2013/071239 |
The present invention is directed to methods of isolating particles, such as nucleic acid-containing particles or microvesicles, from a biological sample and extracting nucleic acids therefrom, wherein the biological sample is cerebrospi...
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WO/2013/070521 |
The present invention relates to biomarkers associated with breast cancer prognosis. These biomarkers include coding transcripts and their expression products, as well as non-coding transcripts, and are useful for predicting the likeliho...
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WO/2013/069495 |
A screening was made intensively on the mutation of COL4A2 gene in 35 Japanese porencephaly patients. As a result, it was found that COL4A2 gene is a causal gene for familial and sporadic porencephaly. An identical hetero mutation of COL...
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WO/2013/068347 |
The present invention relates to the treatment of subjects infected with HCV which have been identified as likely responders to HCV therapy with a miR-122 inhibitor. The invention also provides for prognostic methods for determining the ...
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WO/2013/070230 |
A method and medium for detecting the presence or absence of a targeted strain of antibiotic resistant pathogenic staphylococci in a test sample is provided. The method includes the steps of: a) providing a test medium having at least on...
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WO/2013/068528 |
The invention relates to methods of generating one or more copies of a target polynucleotide molecule, that contains a repeat of identical nucleotides. These methods comprise the steps of : using a primer which hybridizes with a part of ...
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WO/2013/071237 |
A polynucleotide encoding a biosensor polypeptide comprising a modified circularly- permuted thermostable luciferase and a linker linking the C-terminal portion of the thermostable luciferase to the N-terminal portion of the thermostable...
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WO/2013/071119 |
The invention provides methods of diagnosis and prognosis of Alzheimer' disease (AD) in a subject comprising detecting the presence or absence of one or more genetic variations in a sample from the subject, wherein the presence of the ge...
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WO/2013/070962 |
Embodiments include methods for generating a metabolite profile of a stool sample and methods of assessing the status of a subject using the metabolic profile derived from a stool sample.
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WO/2013/070662 |
This invention relates to a rapid method for detection of Salmonella in a sample based on the presence of nucleic acid sequences, in particular, to a PCR-based method for detection, and to oligonucleotide molecules and reagents and kits ...
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WO/2013/069773 |
Provided is a technique that enables bases in nucleic acid to be indirectly labeled at a high labeling rate, while preserving base sequence information for the nucleic acid. Provided is a base-supporting labeling method that involves ind...
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WO/2013/071247 |
Gene signatures for determining whether a neoplasm (such as a multiple myeloma neoplasm) is sensitive to mTORi/HDACi combination therapy and/or for determining the prognosis of a neoplasm in a subject are described. Some embodiments incl...
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WO/2013/071066 |
The present invention provides methods of treating cancer and methods of assessing/monitoring the responsiveness of a cancer cell to a therapeutic compound. The present invention further provides methods of screening for an identifying t...
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WO/2013/070765 |
The invention relates to assays for testing the therapeutic effectiveness of mesenchymal stem cell (MSC) populations by determining the number of GT repeats in the heme oxygenase- 1 (HO-1) promoter region of both alleles.
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WO/2013/070088 |
Methods for monitoring and determining the efficacy of, a treatment for prostate cancer in a subject are provided, such methods including detecting the levels of expression of multiple polypeptide biomarkers in biological samples obtaine...
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WO/2013/070953 |
Multiplex enzyme assay methods and compositions for simultaneously assaying the activities of a plurality of lysosomal enzymes.
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WO/2013/070891 |
A method for indentifying test agents that exhibit prebiotic activity on human skin commensal microorganisms and compositions that include such agents. The method includes providing a test culture of a test agent, a human skin commensal ...
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WO/2013/068107 |
The present invention pertains to a method for lysing a sample to provide a lysis mixture that is suitable for being directly used in a nucleic acid analysis method, wherein the sample is contacted with (a) at least one non-ionic surfact...
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WO/2013/070089 |
Methods for diagnosing the presence of prostate cancer in a subject are provided, such methods including detecting the levels of expression of multiple polypeptide biomarkers in a biological sample obtained from the subject and comparing...
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WO/2013/070115 |
The invention relates to biotechnology, in particular to the production of bacterial preparations and foodstuffs, as well as to medical microbiology and may be used to identify strains of bifidobacteria. A method for identifying speci...
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WO/2013/070894 |
A high-throughput, tiered screening method of indentifying test agents that exhibit prebiotic activity on human skin commensal microorganisms and cosmetic compositions that include such agents. The method includes determining the metabol...
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WO/2013/071224 |
One aspect of the present disclosure relates to a method for determining the amount of a target analyte in a sample. One step of the method can include contacting the sample with a self-cleaving synthetic molecule to form a first treated...
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WO/2013/070849 |
Methods of determining a level of ocular irritation and/or toxicity for a chemical compound are described. Kits for use in methods of determining a level of ocular irritation and/or toxicity for a chemical compound are also described.
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WO/2013/070990 |
The present invention is directed to methods for reducing cross-reactivity between species employed in multiplexed immunoassays.
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WO/2013/066641 |
The invention provides methods and reagents for diagnosing colorectal cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated. In some embodiments, the CNA biomarkers are polyn...
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WO/2013/066039 |
A biomaterial test apparatus includes a disc having a top surface and a bottom surface, and including at least one biomaterial test site, and a magnetic substance disposed in the disc, and including a protruding portion that protrudes to...
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