ANTI-CANCER PHOSPHONATE ANALOGUE - GILEAD SCIENCES INC

Title:

ANTI-CANCER PHOSPHONATE ANALOGUE

Document Type and Number:

Japanese Patent JP2007238624

Kind Code:

A

Abstract:

To provide an anti-cancer phosphonate analogue, relating to compounds having anti-cancer activity.

By a method and a composition which make cells accumulate or hold a biologically active medicine in them, cell targeting can be done. The invention provides a new analogue of an anti-cancer compound. Such new analogues of anti-cancer compounds have all of the usefulness of the anti-cancer compounds, and optionally provide accumulation in cells described below. Furthermore, the invention provides a compound and a method for therapy of cancer or therapeutic activity to cancer.

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Inventors:

BOOJAMRA CONSTANTINE G
CANNIZZARO CARINA E
CHEN JAMES M
CHEN XIAOWU
CHO AESOP
CHONG LEE S
FARDIS MARIA
HUANG ALAN X
KIM CHOUNG X
KIRSCHBERG THORSTEN A
KRAWCZYK STEVEN
LEE CHRISTOPHER P
LIN KUEI-YING
MACKMAN RICHARD L
MARKEVITCH DAVID Y
NELSON PETER H
OARE DAVID
PRASAD VIDYA K
PYUN HYUNG-JUNG
RAY ADRIAN S
SUNDARAMOORTHI SWAMINATHAN
WILLIAM WATKINS
ZHANG LIJUN
ZHANG JENNIFER

Application Number:

JP2007120311A

Publication Date:

September 20, 2007

Filing Date:

April 27, 2007

Export Citation:

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Assignee:

GILEAD SCIENCES INC

International Classes:

C07F9/6558; A61P35/00; A61P43/00; C07F9/40; C07F9/572; C07F9/58; C07F9/60; C07F9/64; C07F9/6506; C07F9/6509; C07F9/6512; C07F9/6518; C07F9/655; C07F9/6561; C07F15/00; C07H3/02; C07H15/252; C07H17/04; C07H19/052; C07H19/056; C07H19/06; C07H19/09; C07H19/12; C07H19/14; C07H19/16; C07H19/167; C07H19/173; C07H19/19; C07H19/23; C07J7/00; C07J41/00; C07J71/00; A61K31/555; A61K31/662; A61K31/704; A61K31/7048; A61K31/7056; A61K31/706; A61K31/7068; A61K31/7072; A61K31/7076

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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