Title:
化合物
Document Type and Number:
Japanese Patent JP2010507640
Kind Code:
A
Abstract:
The invention relates to a novel group of compounds of Formula (I) or a salt thereof: wherein R1, A and HET-1 are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK) such as type 2 diabetes. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by GLK using said compounds and methods for preparing compounds of Formula (I).
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Inventors:
Campbell, Leonie
Pike, Kurt Gordon
Avid, Surman
Walling, Michael James
Pike, Kurt Gordon
Avid, Surman
Walling, Michael James
Application Number:
JP2009533935A
Publication Date:
March 11, 2010
Filing Date:
October 22, 2007
Export Citation:
Assignee:
AstraZeneca Activrag
International Classes:
C07D401/14; A61K31/4155; A61K31/444; A61K31/497; A61K31/536; A61K31/553; A61K31/554; A61P3/04; A61P3/06; A61P3/10; A61P5/50; A61P43/00; C07D403/12; C07D403/14; C07D411/14; C07D413/14; C07D417/14; C07D419/14
Attorney, Agent or Firm:
Shinjiro Ono
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kazuo Shamoto
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita