DIAGNOSTIC MEDICINE FOR SCHIZOPHRENIA - Otsuka Pharmaceutical Co., Ltd.

Title:

DIAGNOSTIC MEDICINE FOR SCHIZOPHRENIA

Document Type and Number:

Japanese Patent JP3943689

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To obtain a diagnostic medicine capable of objectively and accurately diagnosing schizophrenia as a biological marker which is characteristic to schizophrenia by using a sugar acceptor and a sugar donor as an α-1,3-fucose transferase measuring reagent.
SOLUTION: This diagnostic medicine for schizopherenia capable of objectively and accurately diagnosing schizophrenia is obtained by including a sugar acceptor such as an oligosaccharide, a glycolipid or a glycoprotein and a sugar donor such as GDP-fucose as an α-1,3-fucose transferase measuring reagent. Furthermore, a biological marker which is characteristic to schizophrenia is useful as a new clinical diagnosis standard and is expected to contribute to treatment as objective index for pharmacotherapeutics or prognostic prediction if relationship with clinical symptom, prognosis, progress, therapeutic response, or the like is established.

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Inventors:

Yazawa Shin
Hideyuki Asaoka
Tadashi Adachi

Application Number:

JP275398A

Publication Date:

July 11, 2007

Filing Date:

January 09, 1998

Export Citation:

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Assignee:

Otsuka Pharmaceutical Co., Ltd.

International Classes:

C12Q1/48; G01N33/573; G01N33/68; (IPC1-7): C12Q1/48; G01N33/573; G01N33/68

Domestic Patent References:

JP1105160A

Other References:

Eur. Arch. Psychiatry. Clin. Neurosci.,Vol.243,Num.2,P.82-86 (1993)
Glycoconj. J.,Vol.13,Num.6,P.1021-1029 (1996)
Anal. Biochem.,Vol.187,Num.2,P.374-378 (1990)
Cancer,Vol.62,Issue 3,P.516-520 (1988)
Carbohydrate Research,Vol.82,No.2,P.343-351 (1980)

Attorney, Agent or Firm:

Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Asano Yasutaka
Hiromi Matoba
Masaki Murata
Hiroto Yamamoto

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