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Title:
質量分析計
Document Type and Number:
Japanese Patent JP5009784
Kind Code:
B2
Abstract:
A mass spectrometer and method of mass spectrometry are disclosed wherein two separate samples are mass analysed and then the relative intensity, concentration or expression level of one or more components, molecules or analytes in a first sample is quantitated relative to the intensity, concentration or expression level of one or more components, molecules or analytes in a second sample. The relative quantitation is performed probabilistically without the need to resort to using internal calibrants.

Inventors:
Denny, Richard
Richardson, Keith
Skilling, John
Application Number:
JP2007510124A
Publication Date:
August 22, 2012
Filing Date:
May 03, 2005
Export Citation:
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Assignee:
Micromass U.K. Limited
International Classes:
G01N27/62; G01N30/00; G01N30/72; G06F17/18; H01J49/00; H01J49/02
Domestic Patent References:
JP2002078500A
Foreign References:
WO2004019035A2
Other References:
A.I.Nesvizhskii,他,“A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry”,Analytical Chemistry,2003年 9月 1日,Vol.75, No.17,pp.4646-4658
W.Zhang,他,“ProFound: An Expert System for Protein Identification Using Mass Spectrometric Peptide Mapping Information”,Analytical Chemistry,2000年 6月 1日,Vol.72, No.11,pp.2482-2489
C.M.Yanofsky,他,“Determination of the systematic and random measurement error in an LC-FTICR mass spectrometry analysis of a partially characterized complex peptide mixture”,Proceedings of the 26th Annual International Conference of the IEEE EMBS,2004年 9月,pp.216-219
Attorney, Agent or Firm:
Ikeuchi, Sato & Partners