CANCER TREATMENT AGENT INCLUDING MALT1 INHIBITING DRUG AS ACTIVE INGREDIENT

Title:

CANCER TREATMENT AGENT INCLUDING MALT1 INHIBITING DRUG AS ACTIVE INGREDIENT

Document Type and Number:

WIPO Patent Application WO/2023/149450

Kind Code:

A1

Abstract:

The combination of a cytotoxic anticancer agent and/or a molecularly targeted drug, and a MALT1 inhibiting agent that is a compound represented by formula (I) indicated in the specification, or a salt thereof, or a co-crystal, a hydrate, or a solvate thereof, demonstrates a strong antitumor effect, and thus is useful in treating blood cancer.

More Like This:

WO/2006/107859	DIHYDROPYRIDINE COMPOUNDS FOR NEURODEGENERATIVE DISEASES AND DEMENTIA
JP2023052244	MATERIALS AND METHODS OF ENHANCING HEMATOPOIETIC STEM CELL ENGRAFTMENT PROCEDURES
JP2010540439	Fluorine-containing derivatives of hydrogenated pyrido [4,3-b] indoles with neuroprotective and cognitive-enhancing properties, processes for preparation, and use

Inventors:

KOZAKI RYOHEI (JP)
FUJIKAWA RYU (JP)
ONO KAZUYA (JP)
MORISHITA DAISUKE (JP)
SATOH YOSHIHIKO (JP)
MIZUTANI AKIO (JP)

Application Number:

PCT/JP2023/003154

Publication Date:

August 10, 2023

Filing Date:

February 01, 2023

Export Citation:

Click for automatic bibliography generation Help

Assignee:

ONO PHARMACEUTICAL CO (JP)
CHORDIA THERAPEUTICS INC (JP)

International Classes:

A61K31/444; A61K31/5025; A61K45/00; A61P35/00; A61P35/02; A61P43/00

Domestic Patent References:

WO2020111087A1	2020-06-04
WO2021000855A1	2021-01-07
WO2021241611A1	2021-12-02

Other References:

FENG SONG, ZHANG HAISHEN, TANG ZHIYONG, PENG XINGAO, YANG MIN, WEI XUDONG, ZHONG WENGE: "Direct Construction of Chiral Ether via Highly Efficient Heck Reaction and N-Directed Asymmetric Hydrogenation for Large-Scale Synthesis of MALT1 Inhibitor RGT-068A", ORGANIC PROCESS RESEARCH & DEVELOPMENT, AMERICAN CHEMICAL SOCIETY, US, vol. 26, no. 11, 18 November 2022 (2022-11-18), US , pages 3089 - 3095, XP093083206, ISSN: 1083-6160, DOI: 10.1021/acs.oprd.2c00229

Attorney, Agent or Firm:

KAMADA, Mitsunori et al. (JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: LASER PROCESSING METHOD

Next Patent: LASER PROCESSING METHOD