Title:
COMPOSITION FOR PROMOTING MELANIN CONTAINING 2,4-DICHLORO-A-(3,4-DIRYDRO-4-OXO-2(1H)-QUINAZOLINYLIDENE)-Β-OXO- BENZENEPROPANENITRILE
Document Type and Number:
WIPO Patent Application WO/2018/044029
Kind Code:
A1
Abstract:
One aspect of the present invention relates to a composition containing, as an active ingredient, 2,4-dichloro-a-(3,4-dirydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo- benzenepropanenitrile, optical or stereoscopic isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof, for darkening hair color, preventing hair discoloration, and the prevention and treatment of melanin-reducing disease. According to the one aspect of the present invention, a novel use and effect of the 2,4-dichloro-a-(3,4-dirydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo- benzenepropanenitrile can be provided to consumers and related industries can be promoted.
More Like This:
| JP2007507504 | Phenylpyrrolidine ether-based tachykinin receptor antagonist |
| WO/2007/026761 | THIAZOLE DERIVATIVE |
| JP3702493 | QUINAZOLIN-4(3H)-ONE DERIVATIVE |
Inventors:
CHOI HYUN JUNG (KR)
BAE IL HONG (KR)
KIM HYOUNG JUNE (KR)
LEE YOUNG JIN (KR)
LEE TAE RYONG (KR)
CHO DONG-HYUNG (KR)
BAE IL HONG (KR)
KIM HYOUNG JUNE (KR)
LEE YOUNG JIN (KR)
LEE TAE RYONG (KR)
CHO DONG-HYUNG (KR)
Application Number:
PCT/KR2017/009413
Publication Date:
March 08, 2018
Filing Date:
August 29, 2017
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
International Classes:
A61K31/517; A61K8/49; A61Q5/00
Foreign References:
| US20130296349A1 | 2013-11-07 | |||
| US20110015201A1 | 2011-01-20 |
Other References:
FIRESTONE, A. J. ET AL.: "Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein", NATURE, vol. 484, no. 7392, 2012, pages 125 - 129, XP055604991, DOI: 10.1038/nature10936
KIM, E. S.: "Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells", PLOS ONE, vol. 10, no. 2, 11 February 2015 (2015-02-11), pages e0118190, XP055604995, DOI: 10.1371/journal.pone.0118190
CHOI, H.: "Primary cilia negatively regulate melanogenesis in melanocytes and pigmentation in a human skin model", PLOS ONE, vol. 11, no. 12, 11 December 2016 (2016-12-11), pages e0168025, XP055603851, DOI: 10.1371/journal.pone.0168025
KIM, E. S.: "Inhibition of autophagy suppresses sertraline-mediated primary ciliogenesis in retinal pigment epithelium cells", PLOS ONE, vol. 10, no. 2, 11 February 2015 (2015-02-11), pages e0118190, XP055604995, DOI: 10.1371/journal.pone.0118190
CHOI, H.: "Primary cilia negatively regulate melanogenesis in melanocytes and pigmentation in a human skin model", PLOS ONE, vol. 11, no. 12, 11 December 2016 (2016-12-11), pages e0168025, XP055603851, DOI: 10.1371/journal.pone.0168025
Attorney, Agent or Firm:
KIM, Sun-young (KR)
Download PDF: