CYTIDINE DERIVATIVE AND APPLICATION THEREOF - CHANGZHOU FANGYUAN PHARMACEUTICAL CO LTD

Title:

CYTIDINE DERIVATIVE AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2016/078160

Kind Code:

A1

Abstract:

Provided are a cytidine derivative and an application thereof, having the general formula (I): the cytidine derivative has a growth inhibitory effect, confirmed by testing, on transplanted colon cancer HCT-116 tumors borne by nude mice, thus the cytidine derivative has high antitumor activity, while the impact on the body weight of the colon cancer HCT-116 tumor-bearing mice, as well as mortality rate data, prove the low toxicity of the compound.

More Like This:

WO/2007/128874	BIOMOLECULE LABELING REACTANTS BASED ON AZACYCLOALKANES AND CONJUGATES DERIVED THEREOF
JP3481945	INDUSTRIAL APPLICABILITY The conformation-fixed nucleoside analog
JPH06501261	[Title of Invention] Nucleoside derivative

Inventors:

YANG DARIA (CN)
WANG HAIDONG (CN)
LIU XIN (CN)
WANG HUIJUAN (CN)
LIEW SIONG TERN (CN)

Application Number:

PCT/CN2014/093135

Publication Date:

May 26, 2016

Filing Date:

December 05, 2014

Export Citation:

Click for automatic bibliography generation Help

Assignee:

CHANGZHOU FANGYUAN PHARMACEUTICAL CO LTD (CN)
CHANGZHOU UPER BIOPHARMACEUTICAL CO LTD (CN)

International Classes:

C07H19/04; A61K31/7068; A61P35/00

Domestic Patent References:

WO2014078295A1	2014-05-22
WO2004041203A2	2004-05-21
WO1991015498A2	1991-10-17
WO2014148949A1	2014-09-25

Foreign References:

CN1693309A	2005-11-09
CN104119385A	2014-10-29

Attorney, Agent or Firm:

CHANGZHOU JIANGHAI YANGGUANG INTELLECTUAL PROPERTY AGENCY LTD. (CN)
常州市江海阳光知识产权代理有限公司 (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: REACTIVE MONOMER, LIQUID CRYSTAL PANEL AND ELECTRONIC DEVICE

Next Patent: PREPARATION METHOD FOR FLEXIBLE DISPLAY DEVICE