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WO/2020/125478A1 |
The present invention relates to a drug compound, preparation therefor, and an application thereof. The drug has the structure as represented by formula I after being modified by a flavonol structure. Compared with current anticoagulant ...
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WO/2020/131935A1 |
The present disclosure relates to reversal agents, which specifically bind to anti-Factor XI and/or anti-Factor XIa antibodies (e.g., NOV1401), and reverse one or more anticoagulant effects of the anti-Factor XI and/or anti-Factor XIa an...
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WO/2020/124634A1 |
A method employing an edible and medicinal fungus to ferment soybean and other oil crops comprises: inoculating a fermentation medium with an edible and medicinal fungus to perform solid state fermentation so as to obtain a solid-state f...
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WO/2020/122392A1 |
The present invention relates to a composition for preventing or treating a cellular senescence-related disease, comprising zotarolimus as an active ingredient. More specifically, by having confirmed that zotarolimus exhibits a senomorph...
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WO/2020/122393A1 |
The present invention relates to a composition for preventing or treating cellular senescence-related diseases, which comprises, as an effective component, salinomycin which acts differently depending on the type of senescent cells. As s...
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WO/2020/122391A1 |
The present invention relates to a composition for preventing or treating cellular senescence-associated diseases, containing homoharringtonine as an active ingredient. It is ascertained that a composition containing homoharringtonine as...
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WO/2020/122090A1 |
The present invention relates to: a toehold sequence-added nucleic acid aptamer wherein in a nucleic acid aptamer consisting of a single-stranded loop portion and a double-stranded stem portion, a nucleic acid sequence (toehold sequence)...
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WO/2020/113811A1 |
Disclosed are a biopolymer nanosphere containing nicotinamide mononucleotide, a pharmaceutical formulation or a functional food product thereof, a preparation method therefor and the use thereof. The biopolymer nanosphere comprises a bio...
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WO/2020/118055A1 |
The present disclosure is directed to methods of cleansing, decontaminating and/or treating an affected area (such as the mouth, skin, hair, fur, nose, one or both eyes or combinations thereof) of a subject that has been exposed to a che...
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WO/2020/113487A1 |
A healthcare capsule having an auxiliary protection function against radiation hazards, formed by mixing a Ganoderma lucidum extract, cell wall-broken ganoderma lucidum spore powder, a Lycium barbarum fruit, a Hericium erinaceus extract,...
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WO/2020/111089A1 |
Provided is a pharmaceutical composition that has an improved stability of bardoxolone methyl or a pharmaceutically acceptable salt thereof. Use is made of a pharmaceutical composition provided with a coating film, said pharmaceutical co...
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WO/2020/107566A1 |
Provided are a small-molecule protein and a use thereof, wherein the amino acid sequence of the small-molecule protein is as shown in SEQ ID NO.1; and the small-molecule protein is a specially modified and genetically coded magnetic reso...
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WO/2020/109510A1 |
The invention relates to a new family of compounds of the type 2,3-dihydroquinazolin-4(1H)-one and the use thereof as inhibitors of the toxic effects of intracellular-acting toxins, such as ricin, Shiga toxins or the cholera toxin, using...
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WO/2020/112932A1 |
The disclosure is directed to methods of using dantrolene, dantrolene prodrugs, or pharmaceutically acceptable salts thereof, to treat radiation exposure.
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WO/2020/107565A1 |
Provided are a small molecule protein for eliminating oxygen free radicals and the use thereof, wherein the amino acid sequence of the small molecule protein is SEQ ID NO.1; the small molecule can eliminate oxygen free radicals in the bo...
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WO/2020/107204A1 |
A traditional Chinese medicine composition, comprising the following in parts by weight: 60-260 parts of Lonicerae Japonicae Flos, 30-150 parts of Angelicae Sinensis Radix, 15-90 parts of Coicis Semen, 15-75 parts of Persicae Semen, 15-7...
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WO/2020/108481A1 |
Specific embodiments of the present invention provide a thiamine compound, a preparation method and a pharmaceutical composition thereof. The compound has inhibitory effects on Aβ40 and/or Aβ42, and particularly when the benzene ring o...
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WO/2020/112766A1 |
The present disclosure is directed to transdermal compositions comprising a poison antidote, and methods of using such compositions to counteract the effects of a poison.
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WO/2020/111540A1 |
The present invention relates to a pharmaceutical composition for preventing or treating aging or aging-related diseases comprising an anthocyanin-polysaccharide complex and, more specifically, to a pharmaceutical composition for prevent...
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WO/2020/105705A1 |
The present disclosure provides a functional rock or a rock powder thereof, and the use of the functional rock or a rock powder thereof. In one embodiment, the present disclosure provides a powder of the functional rock having a nanoscal...
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WO/2020/103382A1 |
The present invention relates to a multi-disulfide bridge long-chain peptide having neuroprotective activity, a pharmaceutical composition and the uses thereof. The multi-disulfide bridge long-chain peptide that is a very effective neuro...
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WO/2020/097897A1 |
Provided is an application of two genes sirtuin2 and sirtuin4 and proteins thereof in Rhodotorula glutinis for improving mitochondrial function, pertaining to the technical field of biology. Recombinant expression, in mammalian cells, of...
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WO/2020/097723A1 |
The present document describes apple peel polyphenolic extract comprising a proanthocyanidin content of at least 15000 μg/g of dry weight, comprising about 30% to about 35% epicatechin content, and pharmaceutical composition comprising ...
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WO/2020/097739A1 |
Provided herein are nanoparticles including self-assembled cellular components derived from a homogenized plant tissue. Also provided are food powders and other related compositions. Methods for preparing such nanoparticles and food powd...
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WO/2020/095881A1 |
Provided is a novel composition for increasing the retention of a carotenoid in the blood. More specifically, a composition for increasing the retention of a carotenoid in the blood, said composition comprising at least one kind of unsym...
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WO/2020/087687A1 |
A method for preparing 2,2',4,4'-tetrahydroxy-3'-(2",3"-dihydroxy-3"-methylbutyl) chalcone. The steps of the method are: mulberry leaves are submerged and extracted in an aqueous solution of 40-100 % volume percent methanol or ethanol, a...
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WO/2020/087688A1 |
A method for preparing a dihydrofuran chalcone compound, the method comprising the following steps: extracting mulberry leaves by using a methanol or ethanol aqueous solution having a volume fraction of 40-100%; concentrating an extracti...
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WO/2020/089380A1 |
The present invention relates to reversal agents, which specifically bind to the anti-FXIa antibody 076D-M007-H04-CDRL3-N110D as described in WO2013/167669, and neutralize the therapeutic activity of this anti-FXIa antibody, as well as t...
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WO/2020/082220A1 |
Provided are an Enterococcus faecalis having resistance to cephalosporin and high expression of sirtuin 2-like protein and the use thereof. The Enterococcus faecalis EF23 having resistance to cephalosporin and high expression of Sir2-lik...
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WO/2020/085933A1 |
The invention relates to the food industry, specifically to the production of beverages containing inert xenon gas . The beverage contains a liquid medium and an active component, inert xenon gas . The invention is characterised by the f...
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WO/2020/084065A1 |
Aspects of the invention include transdermal delivery devices for delivering a tropane active agent to a subject. Also provided are methods of using the subject transdermal delivery devices, as well as kits containing one or more of the ...
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WO/2020/085459A1 |
The present invention addresses the problem of providing a stronger antioxidation agent, an antiglycation agent and an anti-inflammatory agent that replace imidazole-containing dipeptide. The present invention pertains to an antioxidatio...
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WO/2020/077428A1 |
The present invention describes compounds, the use of compounds in the preparation of a pharmaceutical composition, and a pharmaceutical composition comprising the compounds according to formula A, neutral or ionized derivatives or analo...
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WO/2020/077758A1 |
A fullerene derivative and a preparation method and application thereof. The chemical formula of the fullerene derivative is F(M)n, wherein F is fullerene, M is a group linked to a fullerene (F) skeleton carbon atom by means of a chemica...
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WO/2020/080398A1 |
The present invention provides a food composition or pharmaceutical composition that includes citric acid or a salt thereof as an active ingredient. Intake or administration of the food composition or pharmaceutical composition has been ...
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WO/2020/073975A1 |
Disclosed is a method for extracting a marigold flavonoid. The main steps thereof comprise: extracting marigold flower meal by using a methanol solution, concentrating the extracted solution to a solid content of 5%-30%, and filtering sa...
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WO/2020/073835A1 |
The present invention relates to an anti-IL-6 antibody, a pharmaceutical composition or a kit comprising same, and uses thereof.
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WO/2020/071660A1 |
The present invention relates to: an anti-aging composition, an anti-aging health functional food composition and a feed additive composition which contain an Akkermansia muciniphila strain or a culture thereof as an active ingredient; a...
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WO/2020/051234A9 |
A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the leaf of a plant from the genus Vaccinium.
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WO/2020/062912A1 |
The invention provides a compound conforming to general formula (I) and the application of isomers or pharmacologically acceptable salts thereof in the preparation of a pharmaceutical composition for treating or preventing high altitude ...
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WO/2020/064832A1 |
The present invention relates to the use of imidazolyl ethanamide pentandioic acid for prevention or treatment of radiation-induced damage. The invention further relates to a combination medicament for use in treatment or prevention of r...
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WO/2020/067055A1 |
The present invention addresses the problem of providing an orally-administerable anti-neurodegenerative disease agent having a neuronal growth acceleration action and a neurite extension action, and having excellent transfer properties ...
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WO/2020/053754A1 |
The present invention regards a composition comprising lipoic acid, or an acceptable pharmaceutical or food grade salt thereof or a derivative thereof, and a vitamin D, preferably vitamin D3 and/or vitamin D2, for use in a method for the...
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WO/2020/054204A1 |
Provided is an antioxidant for safely and efficiently reducing oxidative stress in vivo by promoting the expression of an antioxidative enzyme or a redox-related factor in vivo to thereby maintain good health and prevent various diseases...
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WO/2020/054795A1 |
[Problem] To provide: an anti-aging agent which is safe even when ingested for a long period and can prevent the progression of aging effectively; and others. [Solution] The anti-aging agent contains nicotinamide mononucleotide as an act...
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WO/2020/046476A1 |
A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the genus Anacardium.
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WO/2020/042250A1 |
Disclosed is a method for preparing 2,2',4,4'-tetrahydroxy-3-(2"-hydroxy-3"-methylbutyl- 3"-alkenyl)chalcone, comprising the following steps: steeping mulberry leaves with a solution of 40-100% (by volume) methanol or ethanol in water, c...
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WO/2020/043748A1 |
A composition comprising a compound that comprises or consists of a conjugation of 6-hydroxymelatonin and 6- methylsufinylhexyl isothiocyanate is disclosed, as well as this composition for the use as a medicament. Furthermore, this compo...
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WO/2020/046478A1 |
Plant-based inhibitors of MMP-9 that also function as PPAR-γ agonists, and the use of such plant-based inhibitors / agonists in modulating metabolic disorders is disclosed. The plant-based inhibitor / agonist is at least an extract obta...
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WO/2020/036974A1 |
Methods for reducing radiation therapy induced toxicity, e.g., mucositis, in a subject are provided. Aspects of the methods include administering an effective amount of a radiation toxicity-reducing adjuvant to the subject. In certain em...
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