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JP2009108036A |
To provide a new acetylenic compound useful as a raw material for a condensation type polymer having high heat resistance.A compound represented by general formula (1) is disclosed (wherein, the encircled Ar represents an aryl group or a...
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JPWO2007049656A1 |
Provided are a novel fluoroadamantane derivative and a method for producing the same. A method for producing the following compound (2) in which the following compound (1) is reacted with an azide and then heat-treated, a method for prod...
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JP4212473B2 |
A process for the production of (R)- or (S)-aminocarnitine starting respectively from (R)- or (S)-nitryloxycarnitine, through the formation and hydrogenation of the azidocarnitine intermediate with the same absolute configuration is desc...
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JPWO2006118071A1 |
In the urea synthesizer and its modification method, a heavy condenser can be installed at a relatively low position, and the problem of flowing the process fluid into the tube by the condenser can be avoided. NH3And CO2And react with ur...
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JP2008303216A |
To provide a method for producing an intermediate for a bis-platinum (II) complex.The method for producing a polymethylene derivative of chemical formula (III) comprises a step of protecting the nitrogen atom of an -amino acid with a ter...
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JP2008543742A |
The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for pre...
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JP4191879B2 |
Urea is prepared by reacting ammonia and carbon dioxide in an apparatus comprising a vertical condensation and synthesis column (1) and a stripper (21), to provide a urea synthesis solution comprising urea, unreacted ammonia, unreacted c...
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JP2008280263A |
To provide a method for efficiently producing highly pure urea water by a simplified process of only dissolving urea crystals with pure water, without forming a granular urea from urea crystals produced in a urea production process.This ...
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JP4181291B2 |
A compound comprising a substituent of the formula (II) is disclosed as an HIV protease inhibitor. Intermediates for making such compounds and processes for making such intermediates are also disclosed.
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JP4167301B2 |
PCT No. PCT/US97/12552 Sec. 371 Date Oct. 14, 1998 Sec. 102(e) Date Oct. 14, 1998 PCT Filed Jul. 22, 1997 PCT Pub. No. WO98/03518 PCT Pub. Date Jan. 29, 1998Bis-platinum(II) complexes with polymethylene derivatives, the method of making ...
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JP2008239574A |
To provide a method for efficiently producing high-purity urea water by a simplified step consisting merely of diluting an aqueous urea solution formed in the course of urea production with pure water without crystallizing solid urea fro...
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JP4161057B2 |
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JP2008535890A |
The invention relates to poly-substituted tetrahydronaphtalene derivatives of formula (I) and to a method for the production and the use thereof in the form of antiphlogistics.
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JP4138478B2 |
Substituted benzene acetamide compounds and pharmaceutically acceptable salts thereof are useful as glucokinase activators.
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JP2008531613A |
The invention relates to a new class of compounds with action inhibiting carnitine palmitoyl transferase (CPT), pharmaceutical compounds which contain at least one new compound according to the invention, and their therapeutic use in the...
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JP4112056B2 |
The present invention provides an improved process for synthesizing urea from ammonia and carbon dioxide while preventing corrosion of sites, that are to be in contact with a condensate, of the joints of a tube plate and cooling tubes in...
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JP4102471B2 |
A process for the production of polyisocyanates having a biuret structure, comprising continuously combining organic diisocyanates having aromatically attached isocyanate groups in a mixing chamber with organic diamines having aromatical...
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JP4091600B2 |
2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being glucokinase activators which increase insulin ...
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JP2008101002A |
To provide a novel barbituric acid derivative.N-methoxymethyl-5,5-diphenylbarbituric acid is provided. This compound is obtained by a method that comprises N-alkoxyalkylating 5,5-diphenylbarbituric acid with methoxymethyl methanesulfonat...
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JP4084189B2 |
The invention relates to new products of formula (I): in which: Y represents oxygen or sulphur, Z represents C-CH2, CH-CH3 or CH2, R1 represents hydrogen, morpholinyl or the radical. In which the two nitrogen atoms are linear or form a c...
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JP2008094757A |
To provide a method for producing urea from an artificial zeolite by effectively utilizing carbon dioxide generated by a large scale consumption of fossil fuel and becoming a cause of global warming.This method for synthesizing the urea ...
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JP4073489B2 |
The present patent application relates to compounds having formula (I) or a pharmaceutically acceptable salt thereof wherein one of R1, R2 and R3 is a non-cyclic acidic group having a pKa value below 8 or a group which is in vivo convert...
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JP4070270B2 |
Preparation of (cyclo)allophanates containing(cyclo)aliphatic and/or araliphatic isocyanate groups of formula (I) comprises reacting an isocyanate group-containing (oligo)- oxadiazine-trione of formula (II) with primary or secondary alco...
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JP2008509184A |
Compounds of formula I in free or salt form, wherein T, X, R1, R2, Ra, R3, R4, R5 and U have the meanings as indicated in the specification, are useful for treating a condition mediated by CCR-3, particularly an inflammatory or allergic ...
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JP4063333B2 |
Process for the preparation of urea, in which the gas stream which is released during the synthesis of melamine and is composed essentially of ammonia and carbon dioxide is used to synthesize urea, in which process the gas stream which o...
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JP4061018B2 |
The present invention is directed to alkoxyalkylated ureides selected from N-methoxymethyl ethosuximide, N-methoxymethyl glutethimide, N-methoxymethyl-5,5-diphenylbarbituric and the therapeutical uses thereof.
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JP2008050361A |
To provide pharmaceuticals in treating or preventing a disease or condition in which cannobinoid receptor activation plays a role.The present invention relates to naphthalene derivatives of formula (I), wherein X is S, S(O), S(O)2, S(O)2...
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JP4056051B2 |
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JP2008044942A |
To provide a method and device for producing biuret and cyanuric acid.This method and device for producing the biuret having high purity is provided by precipitating crystals by cooling a product formed by a thermal decomposition reactio...
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JP4036271B2 |
PCT No. PCT/EP96/03003 Sec. 371 Date Mar. 9, 1998 Sec. 102(e) Date Mar. 9, 1998 PCT Filed Jul. 9, 1996 PCT Pub. No. WO97/03044 PCT Pub. Date Jan. 30, 1997In a process and an apparatus for preparing (cyclo)aliphatic polyisocyanates contai...
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JP4026674B2 |
The prodn. of biuret gp.-contg. polyisocyanates (I) comprises the catalytic reaction of aliphatic and/or cycloaliphatic di-isocyanates (II) in the presence of OH-acid cpds. (III), with finely-dispersed water as the biuretising agent.
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JP2007320912A |
To provide a method for synthesizing an aryl N-acylurea in high selectivity and high yield and to provide consequential thermal reactions thereof and application in a stepwise synthesis of aryl amides and polyamides. The aryl N-acylurea ...
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JP4013576B2 |
To provide a method for recovering useful substances from waste plastics which can sharply reduce a decomposition time of a polycarbonate resin to realize a recycle treatment of a large amount of the waste plastics mainly composed of the...
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JP4005911B2 |
The present invention relates to compounds of formula (I)wherein U, Y, V, W, L, X, A<1>, A<2>, A<3>, A<4>, A<5 >and A<6 >are as defined in the description and claims and pharmaceutically acceptable salts and/or pharmaceutically acceptabl...
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JP2007530751A |
A process for preparing polyisocyanate prepolymers containing allophanate structural units and prepolymers prepared thereby. The process includes the steps of reacting a) one or more aliphatic and/or cycloaliphatic polyisocyanates with b...
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JP2007530562A |
The present invention relates to polymorphic forms of (1-{3-[3-(4-cyano-3-methoxy-phenyl)ureido]-phenyl}-ethyl)-ca
rbamic acid-2-cyano-1-ethyl-ethyl ester, processes therein, pharmaceutical compositions thereof, and uses therewith.
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JP2007277232A |
To provide a method of industrially advantageously producing an N-nitroisourea or a salt thereof useful for a synthetic intermediate for medicines and pesticides. The method of producing a compound represented by the formula (2) or a sal...
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JP3990755B2 |
Solventless binder combination consists of: (a) a polyisocyanate component (I) with CO groups attached to aromatic groups, (b) a solventless component with NCO groups and optionally ancillaries and additives. The novelty is that (I) cont...
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JP3987607B2 |
In a urea synthesis process comprising reacting ammonia with carbon dioxide at a urea synthesis temperature and pressure in a vertical urea synthesis zone, bringing the resultant urea synthesis solution containing urea, unreacted ammonia...
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JP2007525394A |
Methods and systems for labeling synthesis of phosgen by UV light are provided. Methods of synthesizing labeled compounds useful as PET tracers from labeled phosgen are also provided. The resultant carbon-isotope labeled compounds are us...
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JP2007523929A |
The present invention relates to benzimidazolyl derivatives of formula (I), with the definition of R8, p, Ar1, E, D, R9, q and R10 according to claim 1 , the use of the compounds of formula (I) as inhibitors of one or more kinases, the u...
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JP3960754B2 |
The present invention discloses compounds having the formula wherein one of R<1>, R<2> and R<3> is a acidic functional group having a pKa value below 8 or a group which is convertible in vivo to such a group; and Y represents wherein R<0...
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JP2007520460A |
Methods and reagents for rhodium-promoted carbonylation via isocyanate using carbon-isotope labeled carbon monoxide are provided. The resultant carbon isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Po...
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JP3939763B2 |
A process for preparing biuret-functional polyisocyanates from at least one aliphatic or cycloaliphatic diisocyanate and from at least one amine or water or a mixture thereof as reactants involves mixing the reactants with one another in...
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JP3933214B2 |
To provide a thermally stable polyisocyanate containing allophanate group. The objective polyisocyanate containing allophanate group is produced by reacting (A) a compound containing a urethane group (and essentially free from hydroxyl g...
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JP3908798B2 |
PURPOSE: To obtain new benzocycloalkens having excellent affinity for melatonine receptor and useful as a preventing and treating agent for diseases related to action of melatonin. CONSTITUTION: A compound of formula I [R1 and R2 are eac...
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JP2007084549A |
To provide a novel herbicide and a method for producing the herbicide.The new arylketones of formula (I) can be produced from a precursor amine, and exhibit activities as a herbicide. [In the formula, A1 is a single bond, O or the like; ...
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JP3875320B2 |
To provide an improved polyisocyanate cross-linking agent derived from diphenylmethanediisocyanate and blocked with diethyl malonate. This agent is a polyisocyanate prepared from diphenylmethanediisocyanate and of which at least 95% of t...
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JP3871602B2 |
To obtain a new compound useful as a pigment or a cosmetic. The new compound is expressed by the formula {wherein, (m) and (n) are each 1-20; X and Z are each NH or O; P is 0 or 1; Y is C or S; R1, R'1, R5, R'5, R6, R'6, R7, R'7, R8, R'8...
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JP2006528632A |
This invention relates to stable liquid biuret modified toluene diisocyanates, prepolymers thereof, stable liquid biuret allophanate modified toluene diisocyanates, prepolymers thereof, and to processes for the preparation of these compo...
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