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JP3850895B2 |
PURPOSE: To obtain a compound containing an allophanate group without containing a dimer and a trimer by using a metallic salt of an organic carboxylic acid and an organic phosphorous ester in reacting a compound containing urethane grou...
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JP3851990B2 |
To obtain the subject compound useful as a monomer for the preparation of addition copolymers and free from environmental problem such as toxicity in high production yield and purity. This acryloyl carbamate or acryloylurea is expressed ...
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JP3842132B2 |
N-(4-carbamimidoyl-phenyl)-glycine derivatives have the formula:wherein X and R1 to R5 are as defined herein, and includes hydrates or solvates and/or physiologically acceptable salts thereof and/or physiologically acceptable esters ther...
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JP3839723B2 |
Para-aryl or heteroaryl substituted phenyl amides which are active as glucokinase activators to increase insulin secretion which makes them useful for treating type II diabetes.
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JP2006523194A |
Compound of formula (I): or pharmaceutically acceptable derivatives thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
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JP3827712B2 |
PCT No. PCT/EP94/01008 Sec. 371 Date Dec. 27, 1995 Sec. 102(e) Date Dec. 27, 1995 PCT Filed Mar. 30, 1994 PCT Pub. No. WO94/22807 PCT Pub. Date Oct. 13, 1994A compound having the formula or a pharmaceutically acceptable salt thereof, whe...
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JP2006249095A |
To provide a method for producing a protease inhibitor compound in a more simple and/or inexpensive process.The invention relates to the method of forming a 1,3-diamino-3-substituted-2-propanol chemical intermediate from which various ch...
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JP2006521373A |
The invention relates to a process for the preparation of an alpha-amino carbonyl compound by reacting an imine starting material with a suitable electrophile in the presence of a base. This process has the advantage that the imine start...
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JP2006241272A |
To provide a high-purity fluorinated alkyl group-containing diol having the fluorinated alkyl group in a pendant state and two primary hydroxy groups, to provide a method for producing the same and to further provide a new polyurethane r...
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JP3811523B2 |
To provide a method for joining ammonia to urea capable of reducing energy and investment. An ammonia/urea joining plant comprises an ammonia synthesis gas apparatus 26 for reacting a hydrocarbon supplying raw material with steam and air...
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JP3800248B2 |
PURPOSE: To provide a novel urein derivative retaining the chiral purity of the starting material extremely well which can be obtained by reacting a compound containing a free amino group with a diamino acid derivative containing an Nω-...
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JP3790289B2 |
To provide a novel alkylated (hetero)cyclic compound that has strong affinity to melatonin agonist receptor and is useful for therapy of seasonal depression, sleep disorder and the like. This compound is represented by formula I [R1 is a...
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JP2006143645A |
To provide a method for producing a urea compound free from impurities.The method for producing a urea compound by the reaction of a carbonic acid compound with an alkanolamine comprises the 1st step to add ≥2 mol of the alkanolamine b...
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JPWO2004067500A1 |
Equation (I):(In the formula, X is HSO4Or 1 / 2SO4O-Isopropylisourea sulfate or sulfate and its production method, which are represented by), and these are obtained by reacting cyanamide with isopropyl alcohol in the presence of sulfuric...
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JP2006111589A |
To provide a compound enabling curing by heating or irradiation of active energy beam, having good water resistance and heat resistance after curing and excellent in resistance to hydrolysis and suppressed in production of harmful substa...
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JP3757076B2 |
To provide a urea-containing composition derived from a milk, simply separable and collectable from the milk or a milk material by utilizing a technique of membrane separation and utilizable as a urea material derived from a natural subs...
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JP2006070262A |
To provide micronized (poly) urea for use as a thickening agent in a lubricant.The present invention relates to the method for preparing (poly) urea powder, novel (poly) urea powder, compositions containing such powder, and the use of su...
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JP2006068680A |
To produce a denitrating reductant composition consisting of a high-purity urea aqueous solution by efficiently removing ionic impurities from the high-concentration urea aqueous stock solution prepared by using an inexpensive raw materi...
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JP2006509021A |
The present invention describes compounds of the general formula I as well as processes for their manufacture, pharmaceutical compositions containing them and methods for using these compounds and pharmaceutical compositions as pharmaceu...
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JP2006028037A |
To provide a non-yellowing novel blocked alicyclic polyisocyanate compound and an alicyclic polyisocyanate compound which can be utilized as polyurethane raw materials for elastomers, coating materials, adhesives and the like.The blocked...
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JP3729857B2 |
A process for the preparation of polyisocyanates which contain one or more biuret groups, by reacting a) an aliphatic or cycloaliphatic isocyanate containing two or more isocyanate groups (isocyanate a) with b) a tertiary alcohol or a mi...
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JP3720637B2 |
To obtain the subject inexpensive new compound as an intermediate for producing various guanidine derivatives having insecticidal activity. This new compound is represented by formula I (R1 is a 1-4C alkyl or benzyl; R2 is a 1-4C alkyl; ...
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JP2005534688A |
Process for increasing the capacity of a urea plant comprising a compression section, a high-pressure synthesis section, a urea recovery section, in which a urea melt is formed, and optionally a granulation section, the capacity of the u...
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JP3701780B2 |
To produce a 1,3-disubstituted urea useful as an intermediate for a drug and an agrochemical by reacting a specific cyclic carbonic ester with a specified amine. A cyclic carbonic ester of formula I (R1 to R4 are each H or a 1-5C alkyl) ...
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JP2005247815A |
To provide a method for producing a branched polyphenol compound, having simple production processes, capable of using low-priced raw materials, and therefore economical, and to provide the branched polyphenol compound.This method for pr...
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JP3690180B2 |
To obtain the subject compound at high reaction rate and selectivity by reacting a carbamate with an amine compound in the presence of a base and a quaternary ammonium or phosphonium salt. This compound of formula III is obtained by reac...
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JP3667418B2 |
To obtain granular urea capable of solving problems of water removal in a granulating column method and problems of concentration of diluted formaldehyde in a fluidized bed/spouted bed method by using a specific means in granulating urea...
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JP2005519083A |
The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of...
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JP2005145935A |
To provide a new compound useful also as a developer of a thermosensitive recording material.The salicylic acid derivative is represented by general formula (1), wherein n denotes an integer of 1-11. The manufacturing method of the salic...
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JPWO2003070692A1 |
The following formula (1) [, which has excellent hypoglycemic action, lipid lowering action, and total cholesterol lowering action, and is useful as an active ingredient of a pharmaceutical for the prevention and / or treatment of diseas...
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JP2005089387A |
To provide a compound for a resist and a radiation-sensitive composition, utilizable not only by ultraviolet rays such as i-line and g-line but also by an excimer laser light of KrF or the like, and radiation such as an electron beam and...
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JP2005068106A |
To provide a method for preferentially producing 2,3-di(meth)allylurea from urea and (meth)allyl chloride as principal raw materials and provide a method for efficiently purifying 1,3-di(meth)allylurea from a mixture of (meth)allylureas ...
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JP2005507309A |
A chemical reactor and method of using the same. The reactor comprises first and second micro-engineered discrete flow passages for receiving chemical fluids. The first fluid passage receives a first chemical fluid in which a chemical ch...
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JP2004346055A |
To provide a new method for producing an allylurea, an allylurea-based cross-linking agent and a highly water-absorbing resin.This new method for producing the allyurea is characterized by performing the reaction of an allyamine with ure...
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JP2004339150A |
To provide a method for extremely safely producing allylamine or methallylureas in excellent operability with excellent economy without using allylamine or methallylamine.This method for producing the allylamine or the methallylureas inv...
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JP3594898B2 |
To improve an economy of a melting reduction system by producing methanol from a gas discharged from a melting reduction furnace without eliminating carbon monoxide and supplying hydrogen from another production equipment. The synthesis ...
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JP3583469B2 |
The invention relates to novel ureas and urethanes of Formula I: Formula I which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or i...
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JP3573790B2 |
The subjects of the invention are novel carbodiimides and/or oligomeric polycarbodiimides having terminal isocyanate, urethane and/or urea groups, obtainable e.g. by condensation with elimination of carbon dioxide of 1,3-bis(1-methyl-1-i...
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JP2004528311A5 |
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JP2004528311A |
Substituted diarylureas, pharmaceutical compositions containing them, and their use for stimulating Fas-mediated apoptosis. The compounds, as single stereoisomers or mixtures of stereoisomers, their pharmaceutically acceptable salts, and...
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JP2004528325A |
Novel biphenyl derivatives of the general formula I in which R<1>, R<1'>, R<1''>, R<2 >and n are as defined in claim 1, their stereoisomers and their physiologically acceptable salts or solvates are novel integrin ligands, in particular ...
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JP2004161737A |
To provide a method for continuously producing allophanate-modified diphenylmethane diisocyanate having 19-32% NCO group content and <2 area % urethane content by a GCP analysis.This method comprises the following processes. (1) Performi...
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JP2004148264A |
To solve the following problems that, since the dry type conventional methods where a sludge containing dicyclohexylcarbodiimide and lead components is incinerated together with a drum cannot make the temperature of the whole sludge in t...
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JP2004515538A |
Novel compounds of the formula I in which R1, D, E, W, X and n are as defined in claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of ...
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JP2004513907A |
Couplers for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1):wherein X is selected from halogen and R<5>SO4; R, R<1>, R<2 >and R<5 >are each individually selected from C1 to C22 alkyl and C1 to C2...
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JP2004131456A |
To provide a method for producing a compound useful for various applications, enabling curing by heating and irradiation of active energy beam and making water resistance and heat resistance after curing favorable, and to provide the com...
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JP2004511460A |
The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment ...
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JP2004509162A |
The present invention relates to a compound formula (I) wherein X1 is bond or -O-CH2-, (II) or (III) R<1 >is hydrogen or an amino protective group, a is phenyl, indolyl or carbazolyl, each of which may be substituted with one or two subs...
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JP2004508350A |
The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the prevention and/or treatment of cardiovascular disorders.
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JP2004075679A |
To provide a continuous synthetic method for producing acetylene diuriene (glycoluril), capable of supplying the product in a high yield, scarcely producing by-products, nor causing wastes.This method for producing the acetylenediurene c...
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