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JP4653108B2 |
A process for the preparation of urea comprising adding methanol to a carbon monoxide containing gas, contacting the carbon monoxide-containing gas, methanol and water in at least one shift step in the presence of a catalyst comprising c...
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JP4643567B2 |
A novel method of an amidocarbonylation reaction among an aldehyde compound, an amide compound, and carbon monoxide, which comprises using a palladium-supporting crosslinked-polymer composition containing palladium clusters having a majo...
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JP4632008B2 |
To provide a method for treating triazine compound-containing waste water, also recovering ammonia and carbon dioxide and utilizing them for synthesis of urea. This method for synthesizing urea by treating the triazine compound-containin...
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JP4627959B2 |
To provide a method for synthesizing urea, with which heat recovery can effectively be carried out. This method for synthesizing urea comprises subjecting a urea synthesis solution from a urea synthesis column to stripping with a raw mat...
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JP4619542B2 |
An improved process and intermediate compounds (N) for the preparation of 2-(N,N-disubstituted)amino-4-(perfluoroalkyl)-1,3-oxazin-6-o
ne compounds having structural formula (I) and an improved process for the preparation of 6-(perfluoro...
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JP4614776B2 |
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JP4613157B2 |
Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
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JP2010540552A |
This invention relates to a novel compound which is a glycogen phosphorylase inhibitor and its use in the treatment of diabetes and other conditions associated therewith. The invention further relates to a pharmaceutical composition cont...
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JP2010280595A |
To provide a method for producing high-purity urea which can suitably be used, for example, as a production row material of 1, 3-di(meta) allyl urea.Urea containing oil as an impurity is dissolved into water to provide urea water and the...
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JP2010538044A |
Phenylurea compounds of formula (I): are inhibitors of the enzyme SOAT-1. Cosmetic and pharmaceutical compositions containing them are useful for treating various disorders, such as acne, or have cosmetic applications. An exemplary speci...
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JP4595056B2 |
Disclosed is an improved process for producing nitroisourea derivatives which is necessary for producing nitroguanidine derivatives having an insecticidal activity. Specifically disclosed is a process for producing nitroisourea derivativ...
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JP4589225B2 |
The present invention provides a granulation method with increased drying effect while assuring the pressure for spraying the aqueous solution and the necessary number of nozzles equivalent to those of conventional design. Specifically, ...
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JP2010215590A |
To provide a method of easily producing a compound comprising a ureido group at high yield.There is provided a method of producing a compound comprising a ureido group by the reaction of an isocyanate and ammonia, which reaction is carri...
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JP4545631B2 |
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JP4527424B2 |
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JP4516609B2 |
Disclosed is an industrially advantageous process for producing O-methyl-N-nitroisourea. Disclosed is a process for obtaining O-methyl-N-nitroisourea represented by the following chemical formula (1) or a salt thereof in a high yield by ...
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JP4514293B2 |
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JP4510372B2 |
The invention is directed to acylphenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives.Compounds of the formula Iin which the radicals have the stated meanings, and their physiologica...
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JP4498539B2 |
A process for the production of a thixotropic urea-urethane containing solution (I) comprises reaction of monohydroxy compou (II) with diisocyanate (III) and reaction of the resulting mono-isocyanate adduct with diamines (IV) in aprotic ...
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JP4497572B2 |
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JP4484495B2 |
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JP2010520268A |
There is provided compounds of formula (I), wherein Rx, Ry, X1, X2, L1, L2, Y1 and Y2 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which...
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JP4475003B2 |
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JP2010519287A |
Novel Alpha-halo- and Alpha-alkyl-cyclopropylcarboxy compounds, and uses of these and related compounds in the treatment of a variety of neurological diseases and disorders, and particularly epilepsy, are provided.
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JP4467239B2 |
The invention relates to novel substituted benzoylcyclohexenones of the formula (I) in which Q, R1, R2, R3, R4, R5, Y and Z have one of the meanings given in the disclosure, to processes for their preparation, and to their use.
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JP4451058B2 |
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the invention are useful as modulators of th...
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JP4445856B2 |
The invention relates to a process for the preparation of tetrasubstituted ureas by reaction of the corresponding amines with phosgene in the presence of an aqueous inorganic base at a temperature in the range from 0 to 150° C., which c...
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JP4446689B2 |
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JP4443090B2 |
Preparation of a polyisocyanate with acylurea groups involves reacting an isocyanate (I) with an aliphatic and/or aromatic carboxylic acid in the presence of a metal-salt catalyst at 20-220 degrees C. Preparation of a polyisocyanate with...
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JP2010059137A |
To provide a method for producing meta-cresol-urea adduct, by which impurities taken in the meta-cresol-urea adduct in mixed cresols can easily be washed off.There is provided the method for producing the meta-cresol-urea adduct, charact...
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JP4433694B2 |
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JP2010507636A |
Phenyl derivatives (I) in the form of racemic and/or enantiomeric form and their salts are new. Phenyl derivatives of formula (I) in the form of racemic and/or enantiomeric form and their salts are new. A : heterocyclic moiety of formula...
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JP4426415B2 |
A reactor including a reactor vessel and heat exchange tubes provided in the reactor vessel. The reactor vessel includes a tubesheet and is configured to receive a reaction fluid. The tubesheet has a first plate member configured to cont...
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JP4422034B2 |
This invention relates to tetrahydro-naphthalene derivatives and salts thereof which are useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivatives of the present invention have excellent activi...
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JP4400933B2 |
The present invention provides a process for the preparation of a compound of formula wherein R is a straight or branched alkyl group of from one to twelve carbon atoms; M represents hydrogen or a pharmaceutically acceptable cation; and ...
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JP2009545549A |
The invention provides a new class of compounds capable of inhibiting carnitine palmitoyl transferase (CPT) having formula (I) The invention also relates to pharmaceutical compositions, which comprise at least one new compound according ...
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JP4367988B2 |
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JP4364663B2 |
Disclosed is a method for preparing a 2-hydroxy-6-ureidocarbonyl naphthalene derivative. The method comprises the step of reacting 2-hydroxy-6-aminocarbonyl naphthalene and a isocyanate in an organic solvent at a temperature of 90-200 DE...
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JP4358428B2 |
A urea synthesis process with improved heat economy, wherein a urea synthesis solution obtained by removing most of the unreacted ammonium carbamate by stripping with carbon dioxide at a pressure approximately equal to a urea synthesis p...
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JP4350826B2 |
A process for the production of hydrogen rich gas from a feedstock containing dimethyl ether and/or methanol by steam reforming dimethyl ether in presence of a reforming catalyst to a product gas being rich in hydrogen, wherein necessary...
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JP2009533315A |
What is provided herein is an aromatic compound substitution agent that is a tRNA synthetase inhibitor and thus can be used as an antibacterial agent. The compounds described herein are Gram-positive, Gram-negative, anaerobic or fungal m...
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JP2009533474A |
The present invention relates to a process of preparing indazolyl ureas that are useful as antagonists of the vanilloid receptor subtype 1 (VR1).
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JP4328212B2 |
The invention relates to acyl-3-carboxyphenylurea derivatives, physiologically-acceptable salts, physiologically-functional derivatives thereof and compounds of formula (I), where the groups have the given meanings, the physiologically-a...
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JP4328211B2 |
The invention relates to acyl-4-carboxyphenylurea derivatives, the physiologically-acceptable salts, physiologically-functional derivatives thereof and compounds of formula (I), where the groups have the given meanings, the physiological...
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JP4327929B2 |
A method for preparing urea grease excellent in low noise properties comprises the step of adding a base oil in which an amine (or an isocyanate) is dissolved or dispersed, to a base oil in which an isocyanate (or an amine) is dissolved ...
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JPWO2007122847A1 |
Reagents for organic synthesis and reagents that can carry out chemical reactions in the liquid phase and can easily and inexpensively separate unnecessary compounds from the liquid phase after completion of the reaction. Is to provide a...
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JP4303726B2 |
A process for preparing a compound (C) represented by the following formula: wherein R 1 represents hydrogen, C 1-6 alkyl or C 3-8 cycloalkyl, and R 2 represents hydrogen or methoxy, characterized by reacting a compound (A-1) represented...
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JP4304916B2 |
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JP2009160565A |
To provide a method which targets at a carbon dioxide having a considerable exhaust amount in an exhaust gas among increasing carbon dioxide gases and generates a useful substance by absorbing and decomposing the carbon dioxide.An ammoni...
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JP4270360B2 |
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