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WO/2024/154763A1 |
The present invention provides a compound or a salt thereof for use in preparation of a linker with which it is easy to acquire an antibody-drug conjugate that has a uniform structure and that is stable in blood. As the compound or a sal...
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WO/2024/145687A1 |
Provided herein are, inter alia, proteins comprising unnatural amino acids and arginine, pharmaceutical compositions comprising the proteins, and methods of enhancing the bioreactivity of proteins. In embodiments, the unnatural amino com...
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WO/2024/140282A1 |
The present invention relates to preparation methods for pilocarpine and the intermediate compounds thereof. Specifically, the present invention relates to key intermediates, i.e. compounds of formula (I) and formula (II), for preparing ...
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WO/2024/140776A1 |
Disclosed in the present invention are a preparation method for a stereoisomer and an intermediate thereof, and a preparation method for and the use of the intermediate, in particular the use thereof in the preparation of an active compo...
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WO/2024/141040A1 |
Disclosed in the present invention is a pharmaceutical composition acting as an AXL inhibitor. The pharmaceutical composition comprises a mono-p-toluenesulfonate of a compound as represented by formula (A) or a hydrate thereof serving as...
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WO/2023/196900A9 |
Provided herein are solid forms comprising a compound of formula (I), or a stereoisomer, or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. Also provided herein are methods of synthesizing a compound of...
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WO/2024/143131A1 |
The purpose of the present invention is to provide: an actinic ray-sensitive or radiation-sensitive resin composition which has excellent LWR performance and enables the reduction of residues after development; a resist film, a pattern f...
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WO/2024/130837A1 |
The present invention provides a method for synthesizing an N-acyl amino acid surfactant. The method comprises: mixing a fatty acid, sodium N-methyltaurate and an acid catalyst under high-temperature pressurized conditions, and carrying ...
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WO/2024/128515A1 |
The present invention relates to an antibacterial composition comprising a compound represented by chemical formula 1, the antibacterial composition having improved thermal stability and antibacterial activity.
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WO/2024/124357A1 |
A method of determining a risk of developing a neurological disorder in a Long-COVID patient comprising: (a) testing levels of at least one marker associated with a neurologic disorder in a sample taken from the Long-COVID patient, and (...
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WO/2024/123100A1 |
The present invention comprises: a novel molecule capable of degrading amyloid-beta aggregates; and a brain-targeting amyloid-beta aggregate degradation nanoplatform loaded with the molecule. An amyloid-beta aggregate degrader developed ...
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WO/2024/123928A1 |
This application relates to a novel chlorhexidine lauryl sulfate salt, which provides enhanced chlorhexidine stability and enhanced anti-bacterial activity, and to formulations and methods utilizing the novel salt.
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WO/2024/123848A1 |
A surfactant composition includes greater than 75 wt.% N-acyl aminoalkane sulfonate of formula (I). The surfactant composition is substantially free of solvent and NaCl. A process for preparation of a mixture comprising a N-acyl aminoalk...
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WO/2024/118708A1 |
A method for digesting lignocellulosic material includes combining a lignocellulosic material comprising lignocellulosic biomass, a polymerized naphthalene sulfonate, a sodium xylene sulfonate, and a white liquor comprising sodium hydrox...
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WO/2024/117106A1 |
Provided is a resist composition which generates an acid upon exposure to light, and the solubility of which in a developer is changed by the action of an acid. The resist composition comprises a resin component (A1) the solubility of wh...
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WO/2024/109665A1 |
The present invention belongs to the field of biomedicines. Disclosed are carbamate-bond-containing lipid compounds and the use thereof. The lipid compounds are compounds of the following structure, the definition of each group being as ...
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WO/2024/105421A1 |
α,β-Unsaturated aldehydes are useful products as such in agrochemistry, but also potential intermediates for the preparation of important insect pheromones and kairomones. Until now, primarily the thermodynamically more stable (E)-α,Î...
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WO/2024/106331A1 |
Provided are a method for producing a fluorine-containing sulfonyl chloride and a method for producing a fluorine-containing sulfonyl fluoride that are highly safe and versatile and can provide a fluorine-containing sulfonyl chloride and...
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WO/2024/100964A1 |
Provided are: a new organometallic compound that changes the solubility in solvents through irradiation with light beams having a ultrashort wavelength, and that forms, when being exposed with light beams having a ultrashort wavelength, ...
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WO/2024/094637A1 |
The present invention relates to a process for the preparation of cyclobutenone derivatives of formula (1), wherein Y is O or NH, R is -C(O)-R1 or -S(0)2-R1, and R' is selected from optionally substituted linear or branched C1-12 alkyl, ...
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WO/2024/080603A1 |
The present invention relates to a method for preparing terephthalylidene dicamphor sulfonic acid using electrodialysis. The method for preparing terephthalylidene dicamphor sulfonic acid of the present invention supplies a solution cont...
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WO/2024/070091A1 |
Provided are: a compound suitable for use as a photoacid generator for resist compositions that has favorable sensitivity to actinic energy such as EB and EUV, has excellent resolution in lithography, and can reduce line width roughness ...
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WO/2024/071281A1 |
The purpose of the present invention is to provide: a novel asymmetric fluorinated allyl compound that can be induced to various bioactive medium-sized molecules, and that has high optical purity; and a method for producing the same. Asy...
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WO/2024/068553A1 |
The present invention relates to tertiary amide compounds of formula (II), or a pharmaceutically acceptable salt thereof, wherein R7 comprises a group X which is -S(=O)2OH, -S(=O)OH or -P(=O)(OH)2- The compounds are capable of solubilizi...
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WO/2024/053718A1 |
The present invention employs a resist composition that contains a resin component having a constituent unit represented by general formula (a0-1). In formula (a0-1), R01 is a divalent linking group or a single bond. R02 is an acid-disso...
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WO/2024/048925A1 |
The present invention relates to an organic salt of terephthalylidene dicamphor sulfonic acid, which would be useful in cosmetic compositions for blocking ultraviolet rays, and a preparation method therefor. The present invention provide...
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WO/2024/042157A1 |
Disclosed herein is a compound, or a pharmaceutically acceptable salt thereof, in particular hydrochloride salt thereof, characterized in that said compound is selected from the following compounds: - 4-(4-((1-(3-fluoropropyl)azetidin-3-...
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WO/2024/043121A1 |
The present invention employs a resist composition including: a base material component, the solubility of said base material component in a developing fluid changing due to the action of an acid; and a compound represented by general fo...
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WO/2024/040182A1 |
Disclosed herein is the use of purified 2-S rimantadine or purified 2-R rimantadine or a pharmaceutically acceptable thereof to treat cancers and precancer lesions, including cancers and precancer lesions associated with papilloma virus ...
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WO/2024/032081A1 |
The present invention provides a preparation method for semaglutide, and an intermediate. The preparation method comprises the steps of: (1) reacting compound SEM110 and compound SEM120 in a solvent under an alkaline condition to obtain ...
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WO/2024/029354A1 |
Provided is a novel compound that has photosensitivity such that said compound rapidly decomposes and generates an acid when irradiated with light rays having a wavelength of 20 nm or lower.　A sulfonium salt according to the present in...
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WO/2024/027690A1 |
The present invention provides an intermediate of a bicyclic inhibitor and a preparation method therefor. The present invention particularly relates to an intermediate as shown in formula (VI) and a preparation method therefor. The react...
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WO/2024/029351A1 |
Provided is a fluorene compound having a sulfonic acid ester structure and an allyl group, the compound being represented by formula (1). (In the formula, R1 each independently are a hydrogen atom or a methyl group. R2 each independently...
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WO/2024/024703A1 |
The present invention relates to a resist composition that generates an acid by exposure to light, and that exhibits a change in solubility to a liquid developer through the action of the acid. The resist composition contains a base mate...
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WO/2024/024692A1 |
Provided are a resist film, a pattern formation method, an electronic device manufacturing method that includes the pattern formation method, and an active light-sensitive or radiation-sensitive resin composition satisfying the following...
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WO/2024/023489A1 |
The present invention provides a N-acylated taurine composition comprising: (a) a first N-acylated taurine compound of the formula (IA) or a salt thereof: and (b) a second N-acylated taurine compound of the formula (IB) or a salt thereof...
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WO/2024/018395A1 |
The invention provides methods and certain intermediates for preparing 2-[(4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin-2- yl}piperidin-1-yl)methyl]-1-[(2S)-oxetan-2-ylmethyl]-1H- benzimidazole-6-carboxylic acid 1,3-dihydroxy-2-(hydroxymeth...
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WO/2024/014462A1 |
This resist composition comprises a resin component (A1) that exhibits change in solubility in a developing solution due to the action of an acid. The resin component (A1) has a constitution unit (a0) derived from a compound represented ...
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WO/2024/012244A1 |
Embodiments of the present application provide a local high-concentration electrolyte, a secondary battery, an electronic device, and a mobile apparatus. The local high-concentration electrolyte comprises an electrolyte salt, an organic ...
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WO/2024/011238A2 |
Provided herein are compounds and compositions that inhibit production of trimethylamine (TMA), and methods of using the compounds, e.g., for inhibiting production of trimethylamine, and for treating disorders associated with conversion ...
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WO/2024/002786A1 |
The present invention relates to sulfonated and sulfated compounds obtainable from aryl aliphatic ketones, a process to produce such compounds and the use of these compounds as surfactants, alone or in admixture with other surfactants.
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WO/2024/000060A1 |
The present invention provides novel salts of belumosudil (I) and crystalline forms thereof. Specific salts of belumosudil provided by the present invention include L-malate, acesulfamate, fumarate, maleate, isethionate, malonate, edisyl...
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WO/2024/006701A1 |
A method for preparing dialkyl amino acid ester sulfonates having reduced levels of byproducts, particularly sulfonic acid ester and dialkyl ether, is disclosed. The method involves reacting an amino acid having at least two carboxylic a...
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WO/2023/247268A1 |
The present invention relates to a method for preparing an oligobutyl benzene sulfonate comprising the steps of oligomerization of a butene mix comprising 1-butene and 2-butene to produce an alkene blend which comprises oligobutenes with...
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WO/2023/237382A1 |
The present invention relates to a method for preparing a polyisobutyl benzene sulfonate comprising the steps of alkylation of benzene with a terminal unsaturated polyisobutene to produce a polyisobutyl benzene, sulfonation of the polyis...
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WO/2023/235985A1 |
The present application relates to zwitterion compounds of Formula I, to processes of their preparations, to conjugates thereof, to compositions comprising them and to their use in diagnostics and/or therapy. wherein Q is selected from Q...
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WO/2023/234382A1 |
Provided is a means with which trioxane can be continuously produced at a high yield.　Provided is a composition that contains (A) 58.5-65.5 mass% of formaldehyde, (B) 0.7-4.5 mass% of methanesulfonic acid, and (C) less than 0.007 mass%...
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WO/2023/233273A1 |
The present disclosure relates to a process for preparing a salt of 4-hydroxy pentadecyl benzene sulfonic acid. The process comprises reacting 3-N- Pentadecylphenol with sulphuric acid and neutralizing the 4-hydroxy pentadecyl benzene su...
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WO/2023/225144A1 |
The invention provides piperidinyl-methyl-purine amine salts, crystalline forms, pharmaceutical compositions, their use in inhibiting NSD2, and their use in the treatment of a disease or condition, such as cancer.
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WO/2023/222909A1 |
The inventors have now succeeded in developing arylsulfonium salts, in particular triarylsulfonium salts and dibenzothiophenium salts and a new use of said arylsulfonium salts. These compounds have the advantage of having a thioaryl grou...
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