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WO/2022/159332A1 |
A nanoparticle composition of buckminsterfullerene with ellagic acid is provided that becomes substantially more efficacious to maintain or re-establish benign healthy cellular homeostasis with the functionalization of at least about 10%...
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WO/2022/127550A1 |
Disclosed are hydrogenation catalysts and a method for benzoic acid hydrogenation reaction. The hydrogenation catalysts comprise a carrier, and an active component, auxiliary component and alkali metal element that are loaded on the carr...
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WO/2022/059590A1 |
[Problem] The present invention addresses the problem of providing: a cleavage molecular layer in which adhesion and peeling can be controlled through stimuli other than heat by using a change in bonding in a molecular layer; and a compo...
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WO/2021/216629A1 |
This disclosure relates to processes to form arylcyclopropyl carboxylic acids useful in forming molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda.
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WO/2021/202553A1 |
The disclosure provides compounds, and compositions comprising such compounds, that can be used to treat CXCR5-expressing cancers, especially angioimmunoblastic T cell lymphoma (AICL) and/or cutaneous T cell lymphoma (CTCL).
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WO/2021/112405A1 |
The present invention relates to an isomerization method of a cyclohexane dicarboxylic acid (CHDA) and, more specifically, to a method for preparing a trans-cyclohexane dicarboxylic acid (t-CHDA) from a cis-cyclohexane dicarboxylic acid ...
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WO/2021/079973A1 |
Provided is an onium salt represented by general formula (1). (In general formula (1), X is any n-valent organic group selected from the group consisting of an aromatic group having 6-50 carbon atoms, a heteroaromatic group having 4-50 c...
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WO/2021/062030A1 |
This present disclosure relates to protein kinase C (PKC) modulating compounds, methods of treating a subject with cancer using the compounds, and combination treatments with a second therapeutic agent.
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WO/2020/232742A1 |
Provided is a bifenthrin derivative, wherein same has a structural formula as shown in formula (I). The derivative is obtained mainly through modifying and transforming benzene rings at the ortho-position and terminal-position on an inte...
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WO/2020/138973A1 |
The present invention relates to a method for preparing 1,4-cyclohexanedimethanol. According to the present invention, provided is a method in which a two-stage reduction reaction is performed by means of terephthalic acid as a starting ...
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WO/2020/117519A1 |
A method of making cyclobutane-1,2-diacid building blocks includes using trans-cinnamic acid in its beta form (head to head packing) and photodimerizing the trans-cinnamic acid to create cis-cyclobutane-1,2-dicarboxylic acid (CBDA-4).
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WO/2020/092802A1 |
Compositions and methods for using cyclopropanated structural analogs of fatty acid biofilm dispersal agents are characterized by superior biofilm dispersion. When used in combination with antimicrobials, these analogs decrease the minim...
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WO/2020/068679A1 |
An additive composition comprises one or more calcium cis-1,2-cyclohexanedicarboxylate salts. The calcium 1,2-cyclohexanedicarboxylate salts have a BET specific surface area of 20 m2/g or more. A method for producing a thermoplastic poly...
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WO/2020/054492A1 |
The purpose of the present invention is to provide: a metal salt of an alicyclic dicarboxylic acid that has excellent dispersibility in a polyolefin resin, and as a result, has an excellent crystallinity-improving effect, which is the in...
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WO/2020/050339A1 |
Provided is an industrially useful method for manufacturing (1R,2S)-2-{[((2,4-dimethylpyrimidine-5-yl)oxy}methyl]-2-(3-f
luorophenyl)-N-(5-fluoropyridine-2-yl)cyclopropane-1-carboxa
mide. In the present invention, (1R,2S)-2-{[((2,4-dimet...
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WO/2020/046124A1 |
The present invention is directed to the preparation of phthalic anhydride compounds and the intermediate phthalide compounds. In particular, the invention is directed to an improved bio-based route from furanic compounds to phthalic anh...
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WO/2020/029762A1 |
A preparation method for a fused tricyclic γ-amino acid derivative and an intermediate thereof, and a method for preparing an intermediate of the fused tricyclic γ-amino acid derivative. The fused tricyclic γ-amino acid derivative has...
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WO/2020/009783A1 |
A process for making a high purity salt compound comprises the steps of providing an organic compound, providing a metal hydroxide compound, adding the metal hydroxide compound and organic compound to an aqueous medium, heating the react...
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WO/2019/240393A1 |
The present invention provides a method for isomerizing a cyclohexane dicarboxylic acid by using a zirconia or titania isomerization catalyst.
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WO/2019/240033A1 |
The present invention addresses the problem of providing: a method for producing a dicyclohexanedicarboxylic acid diester, which is capable of suppressing the generation of stereoisomers as by-products, and which is capable of separating...
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WO/2019/240415A1 |
The present invention relates to a method for preparing 3(4),8(9)-bisformyltricyclo[5.2.1.02,6]decane. According to the present invention, a separate catalyst recovery process is not required, and 3(4),8(9)-bisformyltricyclo[5.2.1.02,6]d...
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WO/2019/198779A1 |
A method for producing a 1,4-cyclohexanedicarboxylic acid derivative, comprising the step of concentrating an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid by heating to precipitate the 1,4-cyclohexanedicarboxylic acid der...
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WO/2019/175094A1 |
A cosmetic composition is provided, which comprises a carrier and a Vetiver root extract, in particular an extract from exhausted Vetiver root. This composition provides a stimulation of sebum production, stimulation of sebum antimicrobi...
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WO/2019/171643A1 |
In double decomposition methods and direct methods used in the production of cobalt soaps, there are problems with production costs, and with quality, such as, for example, product purity. One specific problem is that cobalt rhodinate, a...
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WO/2019/161526A1 |
Provided is a one-pot method for preparing twin dicarboxylic acid diamine complex platinum (II) derivatives, the method does not comprise the separation of intermediate carboplatin or carboplatin analogue. Compared with the prior art, ac...
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WO/2019/127700A1 |
An auxiliary alignment agent comprises a homogenous mixture of polycarboxylic acid represented by Formula 1 and a polyamide represented by Formula 2, wherein, in Formula 1 and Formula 2, group A is a cycloalkane or an aromatic hydrocarbo...
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WO/2019/128113A1 |
The present invention provides a 1-O-caffeoylquinic acid derivative represented by formula (II), a 1-O-caffeoylquinic acid, and applications of the 1-O-caffeoylquinic acid derivative represented by formula (II) and salts thereof. The 1-O...
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WO/2018/180696A1 |
The object of the present invention is to provide a method for producing a cis,cis-1,2,4-cyclohexane tricarboxylic acid crystal, wherein a high purity cis,cis-1,2,4-cyclohexane tricarboxylic acid crystal is obtained. This method for prod...
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WO/2018/180854A1 |
The purpose of the invention is to provide a method for producing 1,2,4,5-cyclohexanetetracarboxylic dianhydride with which a high dehydration rate can be achieved stably. This method for producing 1,2,4,5-cyclohexanetetracarboxylic dian...
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WO/2018/071320A1 |
The (1R,3R)- or (1S,3S)-enantiomer of 2,2-dichloro-3-(substituted phenyl)cyclopropane-carboxylic acid is prepared in a process involving chemical resolution of a racemic mixture of a trans-2,2-dichloro-3-(substituted phenyl)cyclopropanec...
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WO/2018/066447A1 |
A method for producing 1, 4-dicyanocyclohexane, which comprises a step for obtaining 1, 4-dicyanocyclohexane by subjecting a thermal concentrate of an ammonia aqueous solution of 1, 4-cyclohexane dicarboxylic acid to a cyanation reaction.
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WO/2018/062854A1 |
The present invention relates to a method for producing 1,3-cyclohexanedicarboxylic acid, wherein the efficiency and economic feasibility of a reaction can be improved by using a catalyst which exhibits excellent activity and has improve...
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WO/2018/032796A1 |
Disclosed is a novel 2-fluorocyclopropane carboxylic acid synthesis method, comprising the following steps: 1) reacting 1,1-dichloro-1-fluoroethane with thiophenol in the presence of alkali to produce a phenyl sulfide intermediate; 2) ca...
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WO/2018/012425A1 |
Provided is a method for manufacturing carboxylic acid or a salt thereof under a moderate condition and in a simple, highly-selective, high-yielding manner. Provided is a method for manufacturing a compound represented by general formula...
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WO/2018/011226A1 |
The invention relates to chemical compositions in the form of an organogel, comprising a gelled organic liquid, comprising or consisting of a volatile organic liquid, and at least one resin acid. The invention also relates to a method fo...
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WO/2018/010932A1 |
The present invention relates to a method of reacting starting materials with an activating group, namely alkanes carrying a leaving group and/or olefins, with carbon dioxide under transition metal catalysis to give carboxyl group-contai...
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WO/2017/179727A1 |
The present invention is a radiation sensitive resin composition which contains a polymer having a first structural unit that contains an acid-cleavable group, a first radiation sensitive acid generator and a solvent, and wherein the fir...
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WO/2017/172957A1 |
Compounds of Formula (I) are estrogen receptor alpha modulators, where the variables in Formula (I) are described in the disclosure. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for tr...
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WO/2017/154947A1 |
In order to provide a high-purity 1,4-cyclohexanedicarboxylic acid powder having excellent powder flow properties, the present invention provides a high-purity 1,4-cyclohexanedicarboxylic acid powder in which: the grain size distribution...
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WO/2017/143946A1 |
Provided are a fatty acid compound, a preparation method therefor and use thereof. The fatty acid compound is of a structure represented by general formula I. The compound has an AMPK activating activity and a capability of inhibiting gl...
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WO/2017/136976A1 |
The present invention discloses an ionic liquid having a methanofullerene carboxylate as an anion, and a preparation method thereof. The ionic liquid is comprised of the methanofullerene carboxylate anion and a quaternary ammonium cation...
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WO/2017/130871A1 |
The present invention provides a method for producing an acid halide solution that is useful when producing a polymerizable liquid crystal compound. This method for producing an acid halide solution includes: a first step of obtaining a ...
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WO/2017/056501A1 |
The present invention provides a method for producing an acid halide solution, which is useful as a production intermediate or the like that enables a polymerizable liquid crystal compound to be produced in an industrially advantageous m...
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WO/2017/035271A1 |
The invention provides compounds having the general formula (I): (I) and pharmaceutically acceptable salts thereof, wherein the variables RAA, n, ring A, X1, L, m, X2, R2, R3, R4, R5, X, and R6 have the meaning as described herein, and c...
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WO/2017/019487A1 |
Provided herein are methods and intermediates for making (lR,2R,5R)-5-amino-2- methylcyclohexanol hydrochloride, which are useful for the preparation of compounds useful for the treatment of a disease, disorder, or condition associated w...
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WO/2016/114707A1 |
The present invention relates to derivatives of dehydroabietic acid useful in treatment ofcardiac arrhythmiaor a hyperexcitablity disease, such as epilepsy or pain, by extracellularly acting on the voltage sensitive domain (VSD) to open ...
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WO/2016/079431A1 |
The invention relates to 2-octylcyclopropyl-1-carboxylic acid, especially in the form of one of the isomers thereof, which is isolated, or in the form of a mixture of at least two of said isomers. The invention also relates to a method f...
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WO/2016/071849A1 |
The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of impurities.
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WO/2016/038379A1 |
The invention relates to pharmaceutical uses of compounds of formula (II). Particular aspects of the invention relate to the use of those compounds in treating, preventing or ameliorating a seizure-related disorder, bipolar disorder, man...
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WO/2016/026014A1 |
The present invention provides a perillic acid derivative in the form of a salt having formula II, with anti-cancer activity, in which the counter-ion M+ comprises alkali or alkaline earth metals, such as Na+ (sodium), K+ (potassium), Ca...
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