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WO/2014/023846A1 |
The present invention relates to a method of preparing a tocopherol or protected tocopherol with a reduced content of phenolic compound or protected phenolic compound, particularly of (2R,3R)-2,3,4,6,7-pentamethyl-2- (4,8,12-trimethyltri...
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WO/2014/023845A1 |
The present invention relates to a method of preparing a tocopherol or protected tocopherol with a reduced content of dehydrotocopherol or protected dehydrotocopherol comprising the step of contacting tocopherol or protected tocopherol i...
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WO/2014/023849A1 |
The present invention relates to a method of preparing a tocopherol with an increased color stability comprising the step of contacting tocopherol in neat or in the form of a highly concentrated solution with an acid activated bleaching ...
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WO/2014/023848A1 |
The present invention relates to a method of preparing a protected tocopherol with a reduced content of free tocopherol, comprising the step of contacting the tocopherol used for the preparation of the protected tocopherol in neat or in ...
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WO/2014/020038A1 |
Disclosed is a method for the synthesis of spiro[2.5]octane-5,7-dione useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed are novel intermediates used in the synthesis of this compound.
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WO/2014/016314A1 |
A compound having the formula (I), for use in treating a disease; a composition comprising said fused quinonic compound of formula (I) and at least one pharmaceutically acceptable carrier; as well as a method of modulating a Janus Kinase...
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WO/2014/017408A1 |
An actinic ray-sensitive or radiation-sensitive resin composition with few pattern collapse, which has an excellent pattern roughness property such as exposure latitude and LWR, and of which the performance over time do not fluctuate muc...
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WO/2014/018826A1 |
A series of novel ketocoumarin photoinitiators are disclosed for use in radiation curing.
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WO/2014/018741A1 |
In certain embodiments, the disclosure relates to heterocyclic flavone derivatives, such as those described by formula provided herein, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure rela...
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WO/2014/015625A1 |
Provided is a method for preparing scutellarin aglycone. In the method, 5,6,7,4'-tetramethoxy flavone is used as raw material, and high purity scutellarin aglycone is obtained through four steps of demethylation, acylation, hydrolyzation...
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WO/2014/014517A1 |
Methods for reducing blood clotting in a subject are provided, including methods to reduce the risk of and/or treat blot clotting pathologies, comprising administering a pharmaceutically-effective formulation of at least one isofonn of a...
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WO/2014/011047A1 |
The invention relates to novel compounds that are useful for modulating mitochondrial morphology and/or expression of OXPHOS enzymes and/or cellular ROS. The compounds are derivatives of TroloxrM wherein the carboxylic acid moiety is rep...
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WO/2014/006407A1 |
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein Z1, Z2, and Z3, Q, R2, A, and R1 are as defined in the claims.
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WO/2014/007186A1 |
Provided is a novel compound having a high lowest triplet excited level (T1 level), a narrow bandgap, and a shallow highest occupied molecular orbital (HOMO) level. A dibenzoxanthene compound is represented by formula [1] described in Cl...
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WO/2014/008192A2 |
The present invention is directed to a method and device to isolate compounds from plant material using vibrational pulsing, vibrational decanting, vibrational sieving and vibrational rinsing. In an embodiment of the invention, a suscept...
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WO/2014/002105A1 |
The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use ...
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WO/2013/189121A1 |
Disclosed is a deuterated benzopyran compound having a structure feature in the formula (I), a pharmaceutically acceptable salt or stereoisomer thereof, or a pre-drug molecule thereof. The compound has excellent anti-inflammatory and ana...
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WO/2013/187673A1 |
The present invention relates to a vitamin E-polyethylene glycol-vitamin B3 conjugate and to an antioxidant comprising same. The vitamin E-polyethylene glycol-vitamin B3 conjugate according to the present invention has improved solubilit...
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WO/2013/185301A1 |
Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.
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WO/2013/188490A1 |
Stabilizer compositions having a chroman-based compound according to Formula (V): and their use in processes for stabilizing organic materials subject to degradation and/or discoloration due to the effects from light, oxygen and heat, an...
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WO/2013/182472A1 |
The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolop...
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WO/2013/182263A1 |
The invention relates to specific phenanthrenes, the use of the compound in an electronic device, and an electronic device containing at least one of said compounds. The invention further relates to a method for producing the compound an...
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WO/2013/175211A1 |
The present invention relates to the prophylaxis of acute noise- induced hearing loss by administering a compound of formula (I): wherein: W is group (Wa), group (Wb) or group (Wc):
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WO/2013/172544A1 |
The present invention relates to: a compound which is a novel two-photon absorbing fluorescent substance; a production method for the compound; a fluorescence sensor and molecular probe able to sense various substrates or enzyme activity...
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WO/2013/172693A1 |
The invention relates to chromatographic extraction of (2R,3R)-dihydroquercetin for production of biologically active additives for medical and pharmaceutical purposes as well as for cosmetics and food industry. A highly productive metho...
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WO/2013/165008A1 |
The present invention provides a small compound that targets at TACC3. The present invention also provides a medicinal agent, particularly an anti-cancer agent, which comprises a small compound that targets at TACC3. A compound represent...
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WO/2013/163835A1 |
A (E)-1-[8-(5-methoxyl-2, 2-dimethyl-2H-benzopyranyl)]-3-(4-methoxyphenyl) -2-propylene-1-ketone as represented by formula I and derivatives thereof, as well as preparation method and uses thereof, the compounds having a tumor inhibition...
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WO/2013/164801A1 |
The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceut...
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WO/2013/161816A1 |
The present invention provides a compound represented by general formula (I) [wherein each symbol is as defined in the description], which has an excellent peripheral blood lymphocyte-reducing activity and is useful for the treatment or ...
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WO/2013/157926A1 |
Title: Geranyl geranyl acetone analogs and uses thereof. Abstract The invention relates to novel therapeutic compounds, more in particular to biologically active analogs and uses thereof as medicament, for instance for the treatment of a...
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WO/2013/157955A1 |
The invention relates to novel therapeutic compounds, more in particular to biologically active analogs and uses thereof as medicament, for instance for the treatment of atrial fibrillation. Provided is a compound of the general formula ...
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WO/2013/157528A1 |
Provided is a medicinal agent comprising a compound represented by general formula (1), a pharmaceutically acceptable salt of the compound or a solvate of the compound or the pharmaceutically acceptable salt. A compound represented by ge...
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WO/2012/084231A9 |
The invention relates to photochromic anellated naphthopyrans having a benzene ring which is adjacent to the pyran acid and is linked to the para substituents via both meta positions, and to use thereof in plastics of all types, in parti...
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WO/2013/146322A1 |
This colored curable composition contains a colored compound containing: (A) at least one type of dye compound selected from a group of compounds represented by general formulas (I-1) and (I-2); and (B) a porphyrin compound represented b...
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WO/2013/144857A1 |
The present application relates to an improved process for the preparation of (S)- equol (1). The present application also relates to novel intermediates of formula (7), (7A), (8) and (9) and their use for the synthesis of (S)-equol.
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WO/2013/141143A1 |
Provided is a novel photochromic compound with favorable durability wherein the color during coloring is an intermediate color (exhibits double peak properties), color intensity is high, and color fading is rapid. For example, a chromene...
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WO/2013/140969A1 |
The present invention is a photoresist composition which contains [A] a polymer that has a structural unit (I) containing an acid-cleavable group and a compound (I) that is represented by formula (1). In formula (1), each of R1, R2, R3 a...
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WO/2013/142236A1 |
Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy.
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WO/2013/139487A1 |
The present invention relates to flavone derivatives and to compositions containing one or more of these flavone derivatives. The present invention further relates to fiavone derivatives or compositions for use in the treatment and/or pr...
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WO/2013/135647A1 |
This invention is in the field of experimental medicine. It provides means and methods for preventing or reducing postoperative adhesions. In particular, it provides a compound according to formula (1) for use in preventing or reducing p...
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WO/2013/127361A1 |
A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (Az 1-15) and alkynes (Ac 1-17). These triazole bridged flavonoid dimers and their ...
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WO/2013/129661A1 |
The present invention provides a chroman derivative represented by general formula (I), which enables the production of an SMTP compound that has a desired structure. In the formula, each of Y1 and Y2 independently represents a hydrogen ...
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WO/2013/130020A1 |
The invention relates to semi-synthetic derivatives of quercetin formula I and pharmaceutically acceptable salts, hydrates and solvates, wherein groups R1 to R5, identical or different, are independently H, benzyl, and at least one group...
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WO/2013/124828A1 |
The present invention provides calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions...
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WO/2013/121209A1 |
A compound of formula I, and its pharmaceutically acceptable salt or salts and physiologically hydrolysable derivatives in free form or salt form: (Formula (I)) wherein either Q1, CR6a and optionally R6b together form a cyclic moiety whe...
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WO/2013/121284A1 |
The present invention concerns an iodinated lipophilic compound of formula (I) or (II) : AG-R (I) or AG-X-R (II) wherein - AG represents an unsaturated or saturated (C8-C52) aliphatic hydrocarbon chain found in fatty acids having or not ...
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WO/2013/113331A1 |
The invention relates to a method for an extraction from wood, having the following steps: providing wood particles of at least one first class and wood particles of a second class, stacking a fine layer consisting of the wood particles ...
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WO/2013/115619A2 |
The present invention relates to a novel compound or a pharmaceutically acceptable salt thereof exhibiting antibacterial activity, an extract comprising the compound from a Penicillium sp. strain, a fraction of the extract, an antibacter...
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WO/2013/110796A1 |
The present invention relates to thiazolidinedione derivatives, to the processes for preparing same and to the therapeutic use thereof for preventing or treating cancer, and more specifically breast cancer. These compounds are of formula...
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WO/2013/111850A1 |
The present invention addresses the problem of providing a compound or a pharmacologically acceptable salt thereof, said compound being to be used for promoting osteogenesis, improving bone metabolism, preventing or treating bone fractur...
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