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WO/2013/018104A2 |
A process for the extraction of Vitamin E from annatto plant matter is disclosed wherein annatto seed matter is subjected, before extraction, to acidification using amla fruit matter. After the acidification, the mixture of the two plant...
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WO/2013/017063A1 |
The polymorphic forms of the compound of Formula I, the preparation thereof including the preparation of the intermediates, the pharmaceutical compositions thereof and the uses of a polymorph above in the manufacture of medicaments for t...
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WO/2013/017068A1 |
Disclosed are a substituted benzopyran derivative and the use thereof. The substituted benzopyran derivative has the structure of formula (I). It has been found in experiments that the derivative can be used to prepare drugs for treating...
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WO/2013/017071A1 |
Disclosed are alicyclic[c] benzopyrone derivatives and uses thereof. The said alicyclic[c] benzopyrone derivatives are compounds represented by formula I or their salts. The present compounds not only significantly improve high activity ...
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WO/2013/014370A1 |
The subject matter of the invention is a novel compound obtained from molecules of the coumarin family, which exhibits rodenticidal activity. The invention also relates to the compositions which incorporate such compounds and also to the...
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WO/2011/154854A9 |
The present invention regards an improved and industrially advantageous process for the preparation of the 2-hyaroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol intermediates, also called "feso chromenyl" and (R)-2-[3-(diisopropylamino...
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WO/2013/013078A1 |
A method of producing alpha-tocotrienol quinone or a stereoisomer thereof, the method comprising selective opening of alpha-tocotrienol chroman to alpha-tocotrienol quinone in the presence of non-alpha tocotrienol chromans by oxidizing a...
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WO/2013/012049A1 |
Provided are a medicinal agent and a food product, both of which prevent heart diseases such as cardiomegaly and heart failure. Specifically provided is an agent for preventing a heart disease such selected from among heart failure, card...
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WO/2013/002879A1 |
The invention provides methods and compositions for inhibiting CD 38 activity, and methods of treating or preventing various disorders associated with CD38 activity.
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WO/2013/000275A1 |
Disclosed are compounds as shown as general formula (I), derivatives and uses thereof, wherein R1, R2, R3, R4, R5a, R5b, R5c and X have the definition as same as the description.
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WO/2013/000846A1 |
The invention relates to a method for producing cyclic enol ethers of formulas (I) and/or (II).
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WO/2013/003168A1 |
This invention relates to novel coumarin derivative, formulations comprising same, and to methods of making and using these compounds and formulations, which are useful as repellents against insects and/or pests. The compounds also preve...
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WO/2012/176856A2 |
To provide a novel pesticide. The present invention provides a compound represented by the formula (I) or its salt, and a pesticide containing it as an active ingredient: (I) wherein each of R1 and R2 is a hydrogen atom, a halogen atom, ...
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WO/2012/176918A1 |
Specifically provided is a chromene compound represented by formula (1), which has a short fading half-life even at low temperatures in a common polymer solid matrix. (In formula (1), R1 represents a hydroxyl group or the like; each of R...
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WO/2012/174622A1 |
The present invention relates to a plant extract obtained from Kielmeyera aureovinosa which has pronounced antibiotic activity. In a second embodiment, the invention describes a novel chemical compound that is isolated from same, and als...
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WO/2012/171652A1 |
The present invention relates to methods for synthesizing vitamin E, and to intermediates thereto.
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WO/2012/171488A1 |
The present invention relates to a coumarin derivative of formula (I): wherein X, Y1, Y2, Y3, R1, R2, R3 and R4 are as defined herein, or a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a phar...
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WO/2012/170430A1 |
The present invention relates to compositions and methods for prophylactic and/or therapeutic treatment of conditions related to mitochondrial function. In various aspects, the present invention comprises administering one or more compou...
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WO/2012/168710A1 |
The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
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WO/2012/151525A9 |
The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with ...
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WO/2012/162945A1 |
The invention discloses mangiferin aglycone crystal form I. X-ray powder diffraction analysis, DSC analysis, TG-DTA analysis, IR analysis and HPLC analysis show that mangiferin aglycone crystal form I is a new crystal form. Mangiferin ag...
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WO/2012/160182A1 |
The invention provides a method of increasing the solubility and/or dispersibility of a quaterrylene and/or terrylene dye in a liquid medium such as, e.g., a liquid medium comprised in a printing ink composition. The method comprises cov...
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WO/2012/161750A1 |
Disclosed herein are environmentally benign surfactants including TPGS-550-M, TPGS-750-M and TPGS-1000-M that comprises of diesters composed of racemic α- tocopherol, MPEG-550, MPEG-750 and MPEG- 1000, respectively, and a succinic acid ...
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WO/2012/162513A2 |
The invention described herein pertains to substituted indenoisoquinoline compounds as described herein, wherein RA, RD, W, X and Y are defined herein, pharmaceutical compositions and formulations comprising the indenoisoquinoline compou...
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WO/2012/157474A1 |
A compound represented by general formula (1) (wherein R1-R4 and a-d are respectively as defined in claim 1); a field effect transistor which is provided with an organic semiconductor layer that contains the compound; and an array for di...
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WO/2012/154564A1 |
The invention relates to fatty acid phenolic derivatives; compositions comprising an effective amount of a fatty acid phenolic derivative; and methods for treating or preventing a metabolic disease comprising the administration of an eff...
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WO/2012/153684A1 |
Provided is a ruthenium complex that is represented by general formula (1*) and is useful as an asymmetric reduction catalyst. (In the formula, * is an asymmetric carbon atom; R1 is an arenesulfonyl group, and the like; R2 and R3 are a p...
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WO/2012/152779A1 |
The present invention relates to a process of separating chiral isomers of chroman compounds, particularly tocopherols and tocotrienols as well as the esters and intermediates thereof. It has been found that this process allows a separat...
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WO/2012/149599A1 |
A photochromic polymer comprising at least two photochromic moieties linked by a straight or branched chain polymer selected from the group consisting of poly(C2 to C4 alkylene oxide), poly[C1 to C10 alkoxy substituted (C2 to C4 alkylene...
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WO/2012/147102A1 |
The present invention relates to bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders. The present invention relates in the field of pharmaceutical composition that pro...
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WO/2012/140243A1 |
The present invention relates to compounds, their use in the treatment or the prevention of viral disorders, including HIV.
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WO/2012/136120A1 |
An aryl acrylamide compound, or a geometric isomer thereof, or a pharmaceutically acceptable salt or hydrate thereof as represented by Formula I, a preparation method therefor, and a pharmaceutical composition containing the compound. Th...
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WO/2012/131010A1 |
Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and their use as antimalarial or antischistosomal agents.
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WO/2012/134724A1 |
Compounds are provided that are either fluorogenic or fluorophoric. Compositions and articles that include the compounds are also provided. Additionally, methods of detecting a microorganism using the compounds are provided. The compound...
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WO/2012/128530A2 |
The present invention relates to novel 2-methyl-2-alkyl-6-amido-2H-benzopyran derivatives having an excellent NF-ĸB target gene expression inhibitory activity and pharmaceutically acceptable salts thereof, a preparation method of the co...
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WO/2012/122969A1 |
Triazene-substituted diphenyl derivatives are suitable as chemotherapeutic agents for treating carcinomas in humans and animals.
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WO/2012/116629A1 |
The present invention relates to a mangiferin aglycon derivative which has a chemical structure as shown in the general chemical structure formula (I), wherein: R1, R2, R3 and R4 are selected from a, b, c or H, and R1, R2, R3 and R4 are ...
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WO/2012/118978A1 |
Provided herein are methods for the treatment of certain cancers in a subject by administering a PI-3 kinase inhibitor, or a combination of a PI-3 kinase inhibitor and a second anticancer agent, to the subject.
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WO/2012/115182A1 |
A compound represented by formula (1) (wherein R1 represents a hydrogen atom or a carboxyl group, R2 represents a hydrogen atom or a hydroxy group, R3 represents a hydrogen atom or a carboxyl group, and R4 represents a hydrogen atom or a...
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WO/2012/111726A1 |
This method for producing a condensate of resorcin and acetone includes: a step for reacting resorcin and acetone in the presence of an acid; and a step for removing, in the presence of an acid, water produced as a byproduct of the react...
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WO/2012/107262A1 |
New dihydrobenzopyran, thiochroman, tetrahydroquinoleine and tetrahydronaphthalene derivatives and their use in anti-cancer therapy with the general formula (I).
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WO/2012/108455A1 |
A method for producing a compound represented by formula (III) or a salt thereof, which is characterized by causing a compound represented by formula (I) or a salt thereof and a compound represented by formula (II) or a salt thereof to r...
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WO/2012/107203A1 |
The present invention relates to the use of nobiletin or a derivative or a hydrate thereof as a sweetener and/or a sweetness enhancer, to sweetener compositions comprising nobiletin or a derivative or a hydrate thereof, and, optionally a...
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WO/2012/104728A1 |
Improved processes for the extraction of quassinoids such as quassin and neoquassin from natural substances containing these compounds are described. The process uses compounds that are Generally Recognized As Safe by the U.S. Food and D...
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WO/2012/104319A1 |
The invention relates to the use of at least one coproduct of the vegetable-oil refining industry for obtaining a purified total unsaponifiable vegetable oil product which is free of the impurities initially found in said coproduct, and ...
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WO/2012/102410A1 |
Provided is a chromene compound that expresses a color that is neutral in tone at the time of coloring, and exhibits small decline in color optical density and excellent photochromic durability in spite of having low initial color, high ...
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WO/2012/102397A1 |
Provided are microcapsules which contain an organic fluorescent agent which absorbs UV-A waves and emits blue light. The shell of the microcapsules includes a polymer or a copolymer of a vinyl-based polyfunctional monomer and/or vinyl-ba...
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WO/2012/102409A1 |
The present invention provides a chromene compound that expresses a color that is neutral in tone at the time of coloring, has a high color optical density, has a fast color fading speed, and has favorable durability. Provided are: a chr...
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WO/2012/101652A2 |
The present invention provides synthetic processes for preparing racemic and/or optically pure epicatechin, epigallocatechin and related polyphenols as such or as their variously functionalized derivatives.
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WO/2012/102937A2 |
The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use i...
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