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Matches 101 - 150 out of 927

Document Document Title
WO/2007/144320A1
Integrated method for the preparation of trioxane from formaldehyde, comprising the steps: a) introduction of a feeding flow A1 containing formaldehyde and water and a return flow B3 consisting essentially of formaldehyde and trioxane in...  
WO/2007/138435A2
This invention relates to an improved process for the preparation of a compound of Formula (I), salts of the free base cis-adamantane-2-spiro-3'-8'-[[[(2'-amino-2'-methyl propyl) amino] carbonyl] methyl]-1',2',4'-trioxaspiro [4.5] decane...  
WO/2007/112451A2
The invention relates to covalent conjugates between endoperoxides and small peptides and organic compounds that bind to molecular cavities on the transferrin or lactoferrin receptor, and the use of compositions comprising these conjugat...  
WO2007068776B1
The invention relates to novel antitumour compounds having general formula (I) and to the corresponding pharmaceutically-acceptable salts, derivatives, pro-drugs and stereoisomers thereof. The inventive compounds can be obtained by isola...  
WO/2007/077479A1
The present invention provides novel spiro trioxane series of general Formula (4). This invention also provides a process for the preparation of novel spiro trioxane series. These novel spiro-trioxane cmpounds useful as anti-malarial age...  
WO/2007/072983A1
A compound having superior solubility and suitable for a liposome contrast medium selective for a lesion such as vascular diseases is provided which is represented by the following general formula (I) wherein R1 to R3 represent an alkyl ...  
WO/2007/051762A1
The invention relates to a process for producing trioxane and at least one comonomer for producing (co)polymers on a trioxane basis, in which, in a first step, formaldehyde and at least one comonomer starting material are reacted in aque...  
WO/2007/023187A1
A method for production of polyoxymethylene homo- or co-polymers by homo- or co-polymerisation of trioxan or additional suitable co-monomers is disclosed, wherein trioxan is firstly produced in a monomer plant, which contains residual mo...  
WO/2007/017479A1
The invention relates to an integrated method for producing trioxane from formaldehyde. According to said method, a flow A1 containing water and formaldehyde and a return flow B2 consisting essentially of water and formaldehyde are intro...  
WO/2007/017410A1
The invention relates to an integrated method for producing trioxane from formaldehyde. According to said method, a flow A1 containing water and formaldehyde as well as a recirculation flow B2 substantially composed of water and formalde...  
WO/2007/014853A1
The invention relates to an integrated process for preparing trioxane from formaldehyde, comprising the steps of: a) feeding a stream A1 comprising water and formaldehyde and a recycle stream B2 consisting essentially of water and formal...  
WO/2007/009388A1
Water-soluble artemisinin derivatives, their preparation methods, the pharmaceutical compositions containing them and the use thereof are disclosed. The artemisinin derivatives have the structure as following(formula I): These compounds ...  
WO/2006/134121A1
The invention relates to a method for producing polyoxymethylene copolymers (POM) or hornopolymers by polymerising suitable monomers. The invention is characterised in that at least one partial amount of the monomers is brought into cont...  
WO/2006/101073A1
[PROBLEMS] To search a substance capable of inhibiting the induction of the expression of GRP78 to find a novel anti-cancer agent. [MEANS FOR SOLVING PROBLEMS] A novel compound represented by the chemical formula 1 is now found as a subs...  
WO/2006/095771A1
Disclosed is a novel gadolinium complex compound exhibiting responsiveness to compounds and ions other than zinc ion. Also disclosed is an MRI probe made of such a gadolinium complex compound. Specifically disclosed is a gadolinium compl...  
WO/2006/081771A1
The invention provides a artemisine derivative of the following formula I, its preparation method and use, as well as a pharmaceutical composition containing such artemisine derivative and its use. The artemisinin derivatives of the pres...  
WO/2006/070381A1
The present invention relates to a novel series of antimalarial amino functionalized 1,2,4-trioxane analogues of formula (4): wherein Ar represents aryl groups such as phenyl, 4-biphenyl, 4-chlorophenyl, 4-methoxyphenyl, 4-methylphenyl a...  
WO/2006/066984A1
Process to prepare a trioxepane compound of the following formula (I) comprising less than 3.5 wt% of dialkyl peroxide based on the total amount of peroxides, said process comprising the steps of reacting a glycol compound of the formula...  
WO/2006/061167A1
The invention relates to a method for producing raw trioxane, comprising the following stages: - a highly concentrated aqueous formaldehyde solution is subjected to an acid catalyzed reaction so as to obtain a trioxane/formaldehyde/water...  
WO/2006/042759A1
The invention relates to a trioxane production method comprising the following stages: catalysed reaction in an acid medium of an aqueous highly concentrated formaldehyde solution (1) in a reactor (R) for obtaining a trioxane/formaldehyd...  
WO/2006/027068A1
The invention relates to a method for producing carbonic acid esters, according to which the intermediate product obtained by reacting urea, a urea derivative or a dialkyl carbonate with a multi-functional alcohol is heated in the presen...  
WO/2006/018302A1
The invention relates to a method for the separation by distillation of pure trioxane from a supply flow (I) containing trioxane in a mass proportion of at least 50 wt. % in relation to the total weight of the supply flow (I), in additio...  
WO/2006/016903A2
Novel substituted 1,2,4-trioxanes and 1,2,4-trioxepanes useful as anti-malarial and/or anticancer agents, and an improved method for their preparation, preferably involving a thiol-olefin co-oxygenation (TOCO) reaction between an allylic...  
WO/2006/007457A2
A system for sintering a tool within a laser sintering system includes a chamber enclosing a sinter material. The laser sintering system grows or sinters the tool from the sinter material in response to signals from a controller. The con...  
WO/2005/077882A1
A chain or cyclic oligolactate having an aminoethyl, hydroxyethyl, or carboxymethyl group in a side chain. A chain oligolactate having an aminoethyl, hydroxyethyl, or carboxymethyl group in a side chain is synthesized first. This chain o...  
WO/2005/066111A1
The invention relates to an intermediate product based on the organic carbonates and carbamates mixture and method for the production thereof. The inventive method consists in reacting a carbamide, a substituted carbamide, a carbamic aci...  
WO/2005/063733A1
The invention relates to a method for separating trioxane from an inlet flow (I) consisting of formaldehyde, trioxane and water. Said method consists in a) preparing an inlet flow (I), which contains formaldehyde as the main component an...  
WO/2005/063353A1
The invention relates to a method for separating trioxane from a mixture containing formaldehyde, trioxane and water. According to said method: the mixture (1) is distilled in a first distillation stage (7) at a pressure of between 0.1 a...  
WO/2005/039599A1
It is intended to provide a novel matrix metalloprotease inhibitor by evaluating the matrix metalloprotease inhibitory effect shown by a cyclic and/or chain polylactic acid mixture. Namely, a matrix metalloprotease inhibitor containing a...  
WO/2005/037257A2
The invention relates to medicinally used substances which specifically inhibit peptidases splitting ala-p-nitroanilide. The invention further relates to the use of at least one such substance or at least one pharmaceutical or cosmetic c...  
WO/2004/108698A1
A process for producing a cyclic lactic acid oligomer having a degree of polymerization of 2m, characterized by (i) reacting a chain lactic acid oligomer having a degree of polymerization of m, which has m structure units derived from la...  
WO/2004/090013A1
A process for efficiently producing a cyclic lactic acid oligomer having a desired degree of condensation. The process comprises reacting the terminal carboxy group of a chain lactic acid oligomer having a degree of polymerization of m (...  
WO/2004/090011A1
A mixture having a composition which enables a cyclic lactic acid oligomer having a desired degree of condensation to be efficiently isolated. The terminal carboxy group of a chain lactic acid oligomer having a degree of polymerization o...  
WO/2004/090014A1
A process for efficiently producing a cyclic lactic acid oligomer having a desired degree of condensation. The process comprises reacting the terminal carboxy group of a chain lactic acid oligomer having a degree of polymerization of m (...  
WO/2004/076401A1
The invention relates to arlylcycloalkyl-substituted alkanoic acid derivatives and the physiologically acceptable salts and physiologically functional derivatives thereof. Disclosed are compounds of formula (I), wherein the radicals have...  
WO/2004/072059A1
The present invention relates to peroxide compositions comprising one or more cyclic ketone peroxides, one or more dialkyl peroxides, and, optionally, one or more conventional phlegmatisers. These compositions are safe and storage stable...  
WO/2004/054998A1
The invention relates to a method for producing trioxane from aqueous formaldehyde solutions in the presence of acid catalysts. The formaldehyde is reacted into trioxane in a reaction column comprising a circulating evaporator. The forma...  
WO/2004/052877A1
The present invention relates to a cyclic ketone peroxide formulation comprising one or more crystallizing cyclic ketone peroxides, one or more co-crystallizing compounds which solidify in said cyclic ketone peroxide formulation at a tem...  
WO/2004/048360A1
A method of synthesizing macrosphelides represented by the following formula which comprises protecting the hydroxyl group of methyl 3−hydroxybutyrate, reducing it into an alcohol, oxidizing the alcohol to give 3−(tert−butyldimethy...  
WO/2004/041201A2
The present invention relates to benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly ...  
WO/2004/039794A1
It is intended to provide a cell activator which has a high biocompatibility and activates cells of mammals including humans without showing any species-specificity, a process for producing the cell activator and an apparatus therefor. A...  
WO/2004/028476A2
In only two steps and in 65% overall yield, natural trioxane artemisinin (I) was converted on gram scale into C-10­carba trioxane dimer (3). This new, very stable dimer was then transformed easily in one additional step into four differ...  
WO/2004/026247A2
Diketo- and pyridine-containing chiral crown ligands having at least two chiral bulky groups attached to two different chiral carbon atoms of the crown that are covalently bonded to or coated on suitable solid supports, and further coate...  
WO/2004/018447A1
An optically active compound having an unsaturated bond at the optically active combining site, wherein the unsaturated bond and a fluorescent substituent or a substituent capable of imparting fluorescence are united in a conjugated stat...  
WO/2004/013121A2
The present invention relates to preparing lactic acid derivatives that are useful as odorants and monomers for polymer synthesis.  
WO/2003/099762A1
The invention provides a method for preventing or reducing the effects of oxidative stress on a substrate. The method includes the step of treating the substrate with a compound of formula (I), or a pharmaceutically acceptable salt there...  
WO/2003/097630A1
The invention relates to a method for producing trioxane by the trimerization of formaldehyde in an aqueous acidic solution and by subsequently separating out trioxane from a mixture (trioxane raw product) essentially consisting of triox...  
WO/2003/087174A2
The invention relates to defined carbocyclic and oxacarbocyclic fumaric acid oligomers. The invention also relates to the use thereof for producing a drug and to drugs comprising the inventive compounds.  
WO/2003/082852A1
In the present invention relates to a novel series of antimalarial 1,2,4-trioxanes analogues of general formula (7), wherein R represents cycloalkyl groups selected from the groups consisting of cyclopentyl, cyclohexyl, cycloheptyl and c...  
WO/2003/076425A1
It is intended to provide antimalarials which have an excellent antimalarial activity with little side effects, particularly show a remarkable antimalarial effect on drug-tolerant malaria parasites, show an improved solubility not only i...  

Matches 101 - 150 out of 927