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WO/2020/210308A1 |
The present disclosure relates to compounds of Formula (I) or (II), which inhibit Gal-3, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compositions.
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WO/2020/209035A1 |
A compound represented by formula (1). R1 is, for example, an alkyl having 1-15 carbon atoms; ring A1 and ring A2 are 1,4-phenylene, etc.; a is 2, etc.; b and c are 0, 1, or 2; Z1 is a single bond, etc.; P1 and P2 are polymerizable group...
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WO/2020/205683A1 |
In immunoglobulin light chain amyloidosis (AL), the unique antibody light chain (LC) protein that is secreted by monoclonal plasma cells in each patient misfolds and/or aggregates, a process leading to organ degeneration. For treating AL...
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WO/2020/189391A1 |
The present invention pertains to: a scytalone dehydratase inhibitor which contains at least one compound selected from the compounds represented by formula (I) (in the formula, A1-A4 each represents CH or N; R is a substituent other tha...
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WO/2020/191091A1 |
This invention provides for compounds of the formula wherein the variables are defined herein, or a stereoisomer, tautomer, N-oxide, hydrate, solvate, or salt thereof, compositions comprising these compounds, and method for the treatment...
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WO/2020/188437A1 |
The present invention relates to compounds with a 5-(2-nitroethyI)-2,4,6- triaminopyrimidine structure, derivatised at the 1 position on the ethylene chain with heteroaromatic or phenyl-benzylether rings. The invention also relates to th...
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WO/2020/188183A1 |
The invention relates to a process for producing a polybenzoxazine monomer, the crosslinking thereof, and the use of the crosslinked product to form ablative thermal protection for a propelling nozzle or a body for atmospheric re-entry.
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WO/2020/188182A1 |
The invention relates to a process for producing a polybenzoxazine monomer, the crosslinking thereof and the use of the crosslinked product to form an ablative thermal protection for a thruster nozzle or an atmospheric re-entry body.
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WO/2020/185420A1 |
Provided herein are integrated methods and systems for the production of acrylamide and acrylonitrile compounds and other compounds from at least beta-lactones and/or beta-hydroxy amides.
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WO/2020/178404A1 |
The present invention relates to herbicidally active pyridazine derivatives of Formula (I) as defined herein, as well as to herbicidal compositions comprising such derivatives, and the use of such compounds and compositions for controlli...
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WO/2020/176505A1 |
The present disclosure relates generally to certain diacylglycerol lactone compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds an...
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WO/2020/175688A1 |
[Problem] To provide a fluorescent probe capable of detecting breast cancer, lung cancer, and squamous cell cancer. [Solution] A fluorescent probe for detecting breast cancer and benign tumors of the breast, the probe containing a compou...
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WO/2020/172258A1 |
Disclosed herein are compounds and compositions having potency in the modulation of Myc family proteins. Such compounds and compositions can be used in the treatment of proliferative diseases, such as cancer, or in the treatment of disea...
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WO/2020/168149A1 |
Disclosed are compounds of Formula (I): or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt or solvate thereof, wherein Q is: (i) halo, cyano, hydroxyl, NRxRx, C(O)OH, C(O)NH2, C1-6 alkyl substituted with zero to 6 R1a, ...
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WO/2020/166875A1 |
The present invention provides a novel compound and an organic light emitting device using same.
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WO/2020/166874A1 |
The present invention provides a novel compound and an organic light-emitting diode using same.
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WO/2020/156363A1 |
The present application discloses an immunomodulator, and specifically discloses a compound depicted by formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The compound provided in the present applicati...
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WO/2020/159019A1 |
The present invention relates to a novel organic light-emitting compound and an organic electroluminescent device using same and, more specifically, to a compound having excellent thermal stability, electrochemical stability, light-emitt...
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WO/2020/158958A1 |
The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexi...
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WO/2020/152067A1 |
Compounds of the formula (I): Q1-Q2-Q3, in which Q1, Q2 and Q3 have the meanings indicated in Claim 1, degrade target proteins, and can be employed, inter alia, for the treatment of diseases such as cancer, multiple sclerosis, cardiovasc...
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WO/2020/151623A1 |
The present invention pertains to the medical field and relates to a compound of formula (III), a stereoisomer or pharmaceutically acceptable salt thereof. The present invention also relates to a method for preparing the compound, a ster...
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WO/2020/151621A1 |
The present invention belongs to the field of medicine, and specifically relates to a compound of formula (I), an isomer or a pharmaceutical salt thereof. This present invention more specifically relates to a compound, a stereoisomer the...
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WO/2020/153669A1 |
The present invention relates to a compound for an organic electric device, an organic electric device using same, and an electronic apparatus thereof. According to the present invention, high luminous efficiency, low driving voltage, an...
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WO/2020/135427A1 |
The present invention relates to a monomer compound represented by formula (I), wherein each variable is as defined in the description. The described monomer is quickly synthesized at a high yield by means of a click chemistry reaction b...
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WO/2020/139001A1 |
The present invention provides a novel aryl-substituted aminomethyloxetenyl amino alcohol derivative or a pharmaceutically acceptable salt thereof. More specifically, the derivative has an effect of promoting ATP production and as such, ...
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WO/2020/135872A1 |
Provided are a drug, a pharmaceutical composition, or a pharmaceutical kit for immunosuppression, for the treatment of conditions such as psoriasis, comprising a forskolin derivative or a salt thereof and optionally a prostaglandin compo...
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WO/2020/138732A1 |
The present invention provides: a compound represented by chemical formula 1; an organic electric device comprising a first electrode, a second electrode, and an organic material layer between the first electrode and the second electrode...
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WO/2020/134138A1 |
The present disclosure relates to the technical field of luminescent materials, and relates in particular to an organic electroluminescent compound, a preparation method therefor and an organic electroluminescent device. In order to solv...
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WO/2020/131689A1 |
Provided herein is a compound of Formula (I), or a salt thereof, wherein R1 is a moiety having the following structure: (II) wherein Z is selected from the group consisting of O and N; X is selected from the group consisting of a bond, N...
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WO/2020/127259A2 |
The present application concerns compounds for use in electronic devices, processes for preparing the compounds, and electronic devices comprising the compounds.
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WO/2020/127194A1 |
Anticancer compounds of formula (I) and derivatives thereof are provided.
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WO/2020/132278A1 |
The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treati...
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WO/2020/127200A1 |
The present invention relates to a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof Formula (I) and to pharmaceu...
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WO/2020/130102A1 |
Antibody preparations for improving or treating autoimmune diseases have been proposed, but the route of administration is limited to intravenous, imposing a burden on the patient. Also, mangiferin has an effect for improving autoimmune ...
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WO/2020/120528A1 |
The present invention provides the compounds having the general formula: (I) wherein R1 to R8, and X are as described herein, compositions including the compounds and methods of using the compounds.
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WO/2020/122908A1 |
An electrochromic medium for use in an electro-optic device comprises a solvent comprising at least one low-volatile organic electrolyte solvent based on a cyclic carbonate ester; an anodic electroactive material; and a cathodic electroa...
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WO/2020/117894A1 |
Enantioselective total syntheses of the anticancer isocarbostyril alkaloids (+)-7-deoxypancratistatin, (+)-pancratistatin, (+)-lycoricidine, and (+)-narciclasine are described. Our strategy for accessing this unique class of natural prod...
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WO/2020/118116A1 |
The present disclosure provides NIR- and SWIR-active small molecule polymethine dyes with improved properties for use in optical imaging, photothermal therapy, and photodynamic therapy.
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WO/2020/110008A1 |
The disclosure relates to inhibitors of PCSK9 useful in the treatment of cholesterol lipid metabolism, and other diseases in which PCSK9 plays a role, having the Formula (I):, or a pharmaceutically acceptable salt, hydrate, solvate, prod...
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WO/2020/111613A1 |
The present invention provides a novel compound and an organic light-emitting diode using same.
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WO/2020/111602A1 |
The present invention provides a novel compound and an organic light-emitting element using same.
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WO/2020/111586A1 |
The present invention provides a novel compound and an organic light-emitting device using same.
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WO/2020/111584A1 |
The present invention provides a novel compound and an organic light emitting diode using same.
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WO/2020/111601A1 |
The present invention provides a novel compound and an organic light-emitting device using same.
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WO/2020/111780A1 |
The present invention provides a novel compound and an organic light emitting device using same.
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WO/2020/111585A1 |
The present invention provides a novel compound and an organic light-emitting device using same.
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WO/2020/111673A1 |
The present invention provides a novel compound and an organic light emitting diode using same.
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WO/2020/111225A1 |
Provided are: a triazine compound having a high glass transition temperature, the triazine compound contributing to the formation of an organic electroluminescent element that exhibits high luminous efficiency and long service life chara...
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WO/2020/106028A1 |
The present specification provides a compound represented by chemical formula 1 and an organic light-emitting device comprising same.
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WO/2020/106102A1 |
The present specification relates to a compound of chemical formula 1 and an organic light emitting diode comprising same.
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