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Document Title |
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JPH09511750A |
A compound and method of making a compound for use as a diagnostic or therapeutic pharmaceutical comprises either a phosphorous or germanium core and at least two hydrazine groups forming a ligand for bonding to a metal extending from th...
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JP2675058B2 |
Ligands and complexes of the title and the applications of these complexes in magnetic resonance imaging, in X-ray radiology and as in-vivo chemical shift agents.
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JP2670621B2 |
PURPOSE:To obtain a material having an absorptivity in a near infrared region by using a dithiotropolonate unsymmetrical metal complex having a specific composition. CONSTITUTION:A metal complex shown by a formula I, where R represents h...
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JP2667666B2 |
The invention provides the use of a physiologically compatible chelate complex of a chelating compound and a paramagnetic ion of a lanthanide element having an atomic number in the range 57 to 70 or of a transition metal having an atomic...
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JP2633944B2 |
A process for the preparation of analytically pure chelate complexes which can be used in diagnostic medicine, for example as contrast agents or radiotherapeuticals, is described. In this process, a complex of a beta -dicarbonyl compound...
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JPH09180918A |
To provide an organic magnetic material exhibiting high reproducibility and ferromagnetism and enabling color adjustment, by causing the organic magnetic material to be expressed by a specified formula and to have such a structure that a...
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JPH09506594A |
In one aspect the invention includes an "antibody cocktail" approach to multi-step targeting of an active agent to a target site. This comprises administering multiple targeting moiety conjugates, wherein the targeting moieties are antib...
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JP2619138B2 |
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JP2613707B2 |
PURPOSE: To obtain a novel bleach and an oxidation catalyst, to provide a method for bleaching a substrate using the oxidation catalyst and a bleaching (detergent) compsn. contg. the catalyst. CONSTITUTION: The catalyst is a manganese-ba...
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JP2604796B2 |
Metal-chelating ligands having the formula or a salt thereof, wherein Y is oxygen or R1 is hydrogen C1-C10 alkyl, aryl-(C1-C10)alkyl, aryl, C1 to C10 alkoxy, hydroxyalkyl with 1 to 10 carbon atoms wherein G is NH2, NCS, NHR4,N(R4)2,CN, w...
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JP2598963B2 |
PURPOSE:To readily obtain the subject compound useful as an infrared ray absorber, etc., in a simple step using an inexpensive raw material, by reacting a tropolone-based compound with phosphorus pentasulfide and then reacting the result...
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JP2586663B2 |
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JP2582341B2 |
PURPOSE: To provide novel chelate compounds having desired chelating properties to many metal ions and useful in therapy, diagnosis or the like. CONSTITUTION: Desired macrocyclic chelate compounds are represented by formula I [wherein R1...
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JPH0940639A |
To produce an arylalkyl hydroperoxide selectively, in high conversion and in high concentration by oxidizing an arylalkylhydrocarbon with an oxygen- containing gas in the presence of a transition metal complex having a specific compound ...
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JPH0930868A |
To obtain a paste by dissolving specific two kinds of organometallic compounds, a substance selected from a terpenoide-based carboxylic acid, etc., having densiness and uniform characteristics, readily making a thin film. This ferrite pr...
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JPH09500899A |
Tris(isonitrile)copper(I) sulfate complexes and their use in synthetic methods for making radionuclide isonitrile coordination complexes such as [99mTc(1-isocyano-2-methoxy-2-methylpropane)6]+. The coordination complexes are useful as ra...
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JPH0920762A |
To obtain a chiral manganese-triazanonane complex, which is a catalyst enabling the production of chiral compounds on an industrial scale. This complex is represented by formula I [u and v are each 1 or 2; w, x and y are each 0, 1, 2, 3;...
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JP2570903B2 |
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JPH09500140A |
Radionuclide chelating compounds are provided for conjugation to targeting molecules such as proteins, peptides or antibodies. The resulting labeled targeting molecules may be used in diagnosis and therapy.
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JPH09500115A |
The present invention provides new and structurally diverse compositions for diagnostic imaging comprising compounds of the general formula: kyl, or C6-C10 aryl, where the alkyl or aryl group may be optionally substituted with one or mor...
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JP2558670B2 |
Metal complexes of hydroxyl- and/or thiol-containing Mannich are prepared by reacting a transition metal-containing agent with an aromatic Mannich. The Mannich is prepared from a substituted hydroxyl- and/or thiol-containing aromatic, an...
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JPH08511248A |
PCT No. PCT/EP94/01377 Sec. 371 Date Mar. 19, 1996 Sec. 102(e) Date Mar. 19, 1996 PCT Filed Apr. 29, 1994 PCT Pub. No. WO94/27978 PCT Pub. Date Dec. 8, 1994The invention relates to new fluorine-containing macrocyclic metal complexes that...
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JPH08511247A |
PCT No. PCT/EP94/01376 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Apr. 29, 1994 PCT Pub. No. WO94/27977 PCT Pub. Date Dec. 8, 1994The invention relates to the use of macrocyclic metal complexes that consist of a c...
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JPH08511237A |
PCT No. PCT/DE94/00372 Sec. 371 Date Dec. 9, 1996 Sec. 102(e) Date Dec. 9, 1996 PCT Filed Mar. 29, 1994 PCT Pub. No. WO94/22493 PCT Pub. Date Oct. 13, 1994This invention relates to new bifunctional chelating agents with intermittent chal...
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JP2556627B2 |
Diagnostic compsns. contg. one or more complex salts (I) dissolved or suspended in an H2O-contg. medium are new, where (I) are salts of the anion of a complex-forming acid and one or more central ions of elements with atomic nos. of 21-2...
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JP2555488B2 |
PURPOSE:To obtain the title complex useful as a drying auxiliary of printing ink, etc., especially printing ink having no change with time and long term storage stability, providing in the presence of drying properties with a small amoun...
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JP2548436B2 |
1. The use of at least one physiologically tolerable paramagnetic complex salt made from aminopolycarboxylic acids having the formulae I to IV see diagramm : EP0169299,P6,F1 N-hydroxyethyl-N,N',N'-ethylenediaminetriacetic acid (HEDTA), s...
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JP2549381B2 |
PURPOSE:To prevent fading from being caused by natural light or a reproducing laser beam and obtain long-time stability, by using a specified dithiol transition metal complex compound as a coloring matter for an optical recording medium....
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JPH08510245A |
2-Pyridylmethylenepolyazamacrocyclophosphonic acid compounds and their derivatives are disclosed which may form inert complexes with Gd, Mn or Fe ions. The overall charge of the complex can be varied to alter the in vivo biolocalization....
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JP2547515B2 |
PURPOSE: To obtain the subject complex which comprises a specific lipohilic macrocyclic complex, is in the form of a steroisomer mixture, is excellent in stability and clearness and is useful as a diagnostic drug or the like. CONSTITUTIO...
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JP2547514B2 |
PURPOSE: To obtain the subject novel compound useful as a ligand for forming a complex of a diagnostic radiopharmaceuticaltechnetium-99m. CONSTITUTION: This novel compound is expressed by formula I [wherein, R1-R9 are each H or 1-8C alky...
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JP2547026B2 |
Pharmaceutical grade amino acid chelates, free of interfering anions, are made by reacting an amino acid ligand with a metal member selected from the group consisting of elemental metals, metal oxides, metal hydroxides and metal carbonat...
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JPH08509976A |
Bicyclopolyazamacrocyclophosphonic acid compounds are disclosed which may form inert complexes with Gd, Mn or Fe ions. The overall charge of the complex can be varied to alter the in vivo biolocalization. Such complexes can be covalently...
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JP2538083B2 |
Electrochemiluminiscent moieties having the formula [Re(P)m(L<1>)n(L<2>)o(L<3>)p(L<4>)q(L<5>)r(L<6>)s]t(B)u wherein P is a polydentate ligand of Re; L<1>, L<2>, L<3>, L<4>, L<5> and L<6> are ligands of Re, each of which may be the same a...
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JP2537502B2 |
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JPH08245668A |
PURPOSE: To obtain a new compound useful as an asymmetric epoxidation reaction catalyst and capable of giving an optically active epoxy derivative useful for medicines and as an intermediate for the medicines in high yield by asymmetrica...
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JPH08231987A |
To inhibit the re-absorption of migrating dyes in the wash liquor without causing discoloration of cotton, polyamide, polyester fibers, etc., by introducing a specified amt. of a specific org. manganese complex into a wash liquor contg. ...
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JP2530112B2 |
PURPOSE: To provide a kit, containing a new technetium-99m compound and useful in the field of evaluating renal functions by using the scintigraphic urography. CONSTITUTION: This packaged kit comprises a container, containing a ligand re...
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JPH08508261A |
New technetium and rhenium chelate compounds are disclosed, as well as a process for preparing the same, radiopharmaceuticals containing these compounds, conjugates of these compounds with substances which selectively accumulate in disea...
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JPH08508263A |
Novel bifunctional chalcogenic-atom-discontinuous chelating agents, pharmaceutical preparations containing them, their use in radio diagnosis and radio therapy, and methods of preparing them. The invention concerns compounds of the gener...
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JPH08508262A |
PCT No. PCT/DE94/00370 Sec. 371 Date Mar. 8, 1996 Sec. 102(e) Date Mar. 8, 1996 PCT Filed Mar. 29, 1994 PCT Pub. No. WO94/22492 PCT Pub. Date Oct. 13, 1994This invention relates to new bifunctional chelating agents with intermittent chal...
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JPH08508048A |
Novel compounds of the formula where G1 and G2 are each independently -OH or -N(R2)2, provided that at least one of G1 and G2 is -N(R2)2, where each R2 is independently hydrogen, alkyl, aryl, acyl or -(A)p-Ra and the other variables are ...
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JPH08217775A |
PURPOSE: To obtain the subject new compound which is a crown thioether, having a specific structure, acting as a ligand of a catalyst for asymmetric synthesis and capable of providing complexes with various transition metals enabling the...
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JPH08507787A |
The present invention relates particularly to novel heterocycle based nitrogen-sulfur ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.
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JPH08507528A |
The present invention relates particularly to novel imidazole based nitrogen-sulfur ligands that are suitable for complexing with a radionuclide, and are useful as general imaging agents for diagnostic purposes.
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JP2523305B2 |
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JP2521215B2 |
PURPOSE: To provide the substantially pure 1:1 L-form transition metal methionine complex. CONSTITUTION: The substantially pure 1:1 L-form transition metal methionine complex is expressed by general formula: [CH3SCH2CH2CH(NH2)COOM]wX (M ...
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JP2520244B2 |
Novel fluorinated diaminoalkyne derivatives are inhibitors of ornithine decarboxylase enzyme and have the following general formula I:wherein R represents C1 - C4 alkyl, or preferably, hydrogen.
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JP2516599B2 |
Complexes formed between a) an amino di- or poly-phosphonate in which phosphonate groups comprise separate carbon atoms and b) a paramagnetic metal ion such as Gd3+, have calcified tissue seeking properties which make them useful as cont...
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JP2512524B2 |
N,N min -bis-(pyridoxal-5-phosphate)-alkylenediamine-N,N min -diacetic acids, N,N min -bis-(pyridoxal-5-phosphate)-1,2-cycloalkylenediamine N,N min -diacetic acids, and N,N min -bis-(pyridoxal-5-phosphate)-1,2-arylenediamine-N,N min -dia...
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