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JPH07502501A |
Disclosed are cationic complexes of Tc-99m and ligands having the structure: wherein: R1 is hydrogen or is selected from the group consisting of C1 to C20 alkyl; C3 to C12 cycloalkyl; C7 to C24 aralkyl; C2 to C16 alkyl ethers, thioethers...
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JPH07502277A |
Complexes of bicyclopolyazamacrocyclocarboxylic acid with Gd, Mn or Fe ions are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complex...
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JPH0720989B2 |
The invention is a chelate of formula I: ember selected from the group consisting of -NO2, -NH2, -NCS, -NHCOCH2-Z, with Z being a member selected from the group consisting of Br and I, -COOH; and -OCH2OOCH; and M is a metal ion selected ...
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JPH07501807A |
The present invention relates particularly to novel aminothiol ligands that are suitable for complexing with a radionuclide, such as Tc, Re, or Ga, and are useful as general imaging agents for diagnostic purposes. The ligands have the ge...
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JPH0714888B2 |
Boronic acid adducts of technetium-99m dioxime complexes are useful for imaging the myocardium, hepatobiliary system, brain and blood pool in humans and other mammalian species.
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JPH0713074B2 |
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JPH07501058A |
PCT No. PCT/US92/09742 Sec. 371 Date Jul. 29, 1994 Sec. 102(e) Date Jul. 29, 1994 PCT Filed Nov. 9, 1992 PCT Pub. No. WO93/08839 PCT Pub. Date May 13, 1993A class of diagnostic and therapeutic compounds derived from phosphinimines that i...
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JPH0726291A |
PURPOSE: To inhibit the re-absorption of a migrating dye in a wash liquor containing a peroxide-containing detergent by incorporating a specified manganese compound in the wash liquor. CONSTITUTION: There is provided a method for inhibit...
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JPH07500816A |
PCT No. PCT/FR92/00718 Sec. 371 Date May 19, 1994 Sec. 102(e) Date May 19, 1994 PCT Filed Jul. 25, 1994 PCT Pub. No. WO93/01839 PCT Pub. Date Apr. 2, 1993.The invention concerns a radiopharmaceutical product having in particular a cerebr...
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JPH075505B2 |
@ A process for preparing hydrocarbon-soluble transition metal salts of organic carboxylic acids having improved properties wherein the transition metal is one capable of having a multiplicity of oxidation states is described. The proces...
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JPH0692423B2 |
Novel vicinal dioxyalkylene organometalates comprising a cation having a hydrocarbyl-containing substituent are disclosed. The vicinal dioxyalkylene organometalates can be reacted with water to yield alkylene glycols.
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JPH0684447B2 |
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JPH0676364B2 |
Novel propylene amine oxime ligands have the formulawhere each of R,, R2, R3, R4, R5, R6, R7 or R8 may be hydrogen, hydrocarbon, carboxyl, amine, amide or nitrile, provided that, if R, is the same as R9 and R2 is the same as R7, then Ra ...
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JPH0676363B2 |
A family of propylene amine oxime ligands has the formula 2wherein preferably R1 is C1-C4 alkyl or phenyl and each of R, R2, R3 and R4 is H or C1-C4 alkyl. The technetium-99m complexes of these ligands are lipophilic neutral complexes us...
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JPH06507904A |
Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspendin...
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JPH06247993A |
PURPOSE: To obtain an optically active epoxide useful for a synthetic intermediate for medicines, agrochemicals, etc., ferroelectric liquid crystal, etc., by reacting an olefin compound with oxygen in the presence of both an optically ac...
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JPH0662446B2 |
A method of. imaging organs with 99mTc radiopharmaceuticals, especially of hepatobiliary imaging and negative myocardial infarct imaging in a mammal, which comprises administering to the mammal a hepatobiliary or myocardial imaging amoun...
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JPH0662555B2 |
Protein conjugated chelated metal radionuclides are provided for use in vivo. Intermediates are provided for preparing the polypeptide compositions efficiently.
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JPH0660469B2 |
A process for the photochemical stabilization of undyed and dyed polyamide or polyurethane fibre material that is characterized in that the fibre material is treated with a water soluble, organic copper, manganese or nickel complex that ...
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JPH06220079A |
PURPOSE: To provide new compounds useful in the radiotherapy of liver tumor or the like and having suitable half-life and specific radioactivity. CONSTITUTION: A compound of formula [wherein R is a (cycloalkyl- or aryl- substituted) 1-10...
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JPH06211761A |
PURPOSE: To obtain aryl and heterocyclic substituted propenamide derivs. useful for the treatment of ischemic conditions and arrhythmia and having potassium channel-activating action. CONSTITUTION: The aryl and heterocyclic substituted p...
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JPH0655700B2 |
Tertiary butyl esters for use an anticancer drugs have the formula: wherein R1 and R2 are the same or are different and each is H, Cl, F, Br or I, and R2 may also be NH2; R3, R4 and R5 are the same or are different and each is H, F, Cl, ...
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JPH06506449A |
PCT No. PCT/EP92/00698 Sec. 371 Date Sep. 24, 1993 Sec. 102(e) Date Nov. 24, 1993 PCT Filed Mar. 27, 1992 PCT Pub. No. WO92/17215 PCT Pub. Date Oct. 15, 1992.An imaging contrast medium comprising a physiologically tolerable multinuclear ...
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JPH0653750B2 |
Tris(isonitrile)copper(I) complex salts with anions selected from BF4, PF6, ClO4, I, Br, Cl and CF3COO are useful in preparing radionuclide complexes rapidly at room temperature. Preferred isonitrile ligands are ether isonitriles. The tr...
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JPH06181890A |
PURPOSE: To provide an MRI opaque substance which has a sufficient opaque capacity in a physiologically permitted opaque substance concn. region and with which useful image information is obtainable by using a polyamine metal complex com...
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JPH06505268A |
(57) [Summary] Since this publication is application data before electronic filing, summary data is not recorded.
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JPH0645632B2 |
Homologs of Diamide-DTPA-Paramagnetic compounds (such as diamido acetyl diethylene triamine triacetic acid) provide excellent contrast agents for magnetic resonance (MR) imaging. The magnetic dipole generated by the unpaired electron wit...
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JPH0643432B2 |
A method for preparing a coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, lr, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta is disclosed. The method comprises preparing a soluble metal adduct of sa...
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JPH0637394B2 |
Difluoronucleosides are useful for treating neoplasms in mammals.
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JPH06121933A |
PURPOSE: To obtain an improved transition metal catalyst for bleaching and oxidation of various stains at low temp., to obtain a bleaching-detergent compsn. contg. the catalyst and to provide a method for bleaching and/or cleaning substr...
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JPH0633292B2 |
The invention relates to novel complex compounds of elements from groups VII A, VIII A and I B of the Periodic Table with the trisodium salt of tris(m-sulphophenyl)phosphine as complex ligands, and to the use of these complex compounds a...
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JPH0627107B2 |
Norborane derivatives of the formula: wherein substituents A, B, X and Y each are independently selected from hydrogen, hydroxyalkyl (wherein the alkyl group contains 2-6 carbon atoms), methylenephosphonic, methylene-, ethylene- and prop...
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JPH06502640A |
The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to a radiopharmaceutical compositions comprising the complexes, to the use of the compositio...
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JPH0673061A |
PURPOSE: To efficiently obtain 6-substituted optically active dihydroepoxybenzopyrane useful as an intermediate for preparation of a compound having potassium channel opening characteristics by reacting specific chromene with a specific ...
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JPH0673081A |
PURPOSE: To obtain the complex for optical storage medium of data or the like which shows spin transition with thermal excitation, contains an optical isomerizing double-bond, is bonded to a ligand atom by π electron system, and which c...
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JPH0673060A |
PURPOSE: To provide a new compound useful for chemically modified electrodes etc. CONSTITUTION: The objective compound of formula I [Ar and Ar' are each (substituted) aromatic group; X is counteranion for manganese], which can be obtaine...
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JPH06501677A |
The present invention relates to novel technetium-99m complexes and to methods of preparaing the complexes. The present invention further relates to radiopharmaceutical compositions comprising the complexes, to the use of the composition...
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JPH06501450A |
PCT No. PCT/DE91/00470 Sec. 371 Date Jan. 29, 1993 Sec. 102(e) Date Jan. 29, 1993 PCT Filed May 31, 1991 PCT Pub. No. WO91/18908 PCT Pub. Date Dec. 12, 1991The invention relates to cyctopentadienylcarbonyl99mTc complexes of general formu...
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JPH0641150A |
PURPOSE: To provide the compound which is useful for stabilizing undyed or dyed fiber materials. CONSTITUTION: The metal complex salt of formula (R1 is H, alkyl or aryl; R2 is H, alkyl or aryl; Me is Cu, Mn or Ni) and its alkali metal sa...
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JPH0624972A |
PURPOSE: To obtain a new comps. useful for a metallic complex and a diagnostic agent and useful to treat a tumor, etc. CONSTITUTION: This new compd. is a compd. represented by formula I [where R<1> is H or an (OH substd.) 1-6C alkyl, R<2...
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JPH0625260A |
PURPOSE: To provide a new compd. useful as photochemical stabilizers for polyamide fibers or a mixture of polyamide fibers and other fibers. CONSTITUTION: This compd. of the formula (where R1 is H, (substd.) alkyl or aryl; X is O or S; a...
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JPH05320147A |
PURPOSE: To provide a new compound capable of rapidly forming a metal complex stable in vivo and useful as an agent for cancer treatment by bonding to a specific antibody, etc. CONSTITUTION: The compound of formula I (n is 1 or 2; R1 is ...
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JPH05508162A |
(57) [Summary] Since this publication is application data before electronic filing, summary data is not recorded.
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JPH05301878A |
PURPOSE: To provide an optically active modification of a benzopyran compound useful as an intermediate for pyranobenzoxadiazole as a hypotensive agent. CONSTITUTION: The objective optically active modification a benzopyran compound of f...
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JPH05507906A |
Technetium-99m complexes of crown thioethers having 3 to 6 donor sulphur atoms joined into a macrocyclic ring by C2 or C3 groups, for example 1,4,7-trithiacyclononane (9S3); and of tripodal ligands having more than 3 donor sulphur atoms ...
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JPH0576953B2 |
Complexes useful as radiopharmaceuticals contain the <99m>Tc-NO moiety and a ligand which confers biological target-seeking properties on the complex. Preferred are mono-cationic complexes, particularly having the formula [<99m>Tc(NO)L2X...
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JPH05255339A |
PURPOSE: To readily obtain the nitrated phthalocyanine compound useful as a raw material for the recording films of CD-corresponding additional storage type optical disks excellent in stability and further in the recording characteristic...
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JPH05506426A |
There are provided novel chelating agents useful in the preparation of contrast media for diagnostic imaging or of radiotherapeutic or detoxification compositions.
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JPH05239039A |
PURPOSE: To form a complex of technetium or rhenium having high stability in a neutral pH range by using a specified large ring complexing agent. CONSTITUTION: The labeling substance (particularly, monoclonal antibody or the fragment) is...
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JPH05239001A |
PURPOSE: To produce a new barium-containing manganese oligomer having a magnetic property especially suitable for applying to a magnetic thermometer and a magnetic fluid. CONSTITUTION: A compd. expressed by formula I ((x) is an integer o...
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