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WO/2010/018474A2 |
The invention relates to a novel ester, the 3,5-di-tertiobutyl-4-hydroxybenzoate of 3,4,5-trihydroxy-6-methoxytetrahydropyran-2-yl methyl defined by the following formula (I). The invention also relates to the method for preparing the co...
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WO/2010/016587A1 |
Disclosed is a method for accurately evaluating the specific incorporation of D-glucose into cells. The method is characterized by: contacting each of a D-glucose derivative that can be incorporated into cells specifically and has a flu...
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WO/2010/009499A1 |
The present specification relates to the production of cotton plants and seeds and oil prepared therefrom having elevated levels of oleic and reduced levels of palmitic and linoleic acids. Furthermore, cottonseeds having low levels of cy...
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WO/2010/009500A1 |
The specification relates to plants and their seeds and oil obtained therefrom, and to methods of producing same comprising oil having modified fatty acid compositions, such that 28 % to 80 % of the total fatty acid content in the seedoi...
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WO/2010/007213A1 |
The invention describes novel reagents that can be applied for analysis of the quality of human cells. The method evaluates the integrity of the plasma membrane of the cells by detecting novel glyco structures found only intracellularly....
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WO/2010/004269A2 |
The invention relates to a process for the preparation of a compound of general formula (IV) wherein OX, R3 and R3' are defined herein; and to the use of compounds of general formula (IV) as intermediates in processes for the stereospeci...
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WO/2010/000013A1 |
The present invention relates to a sulfated polysaccharide compound and the preparation and use thereof, and in particular to a narrow distribution low molecular weight, highly sulfated pentosan (in this instance a xylan) referred to as ...
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WO/2009/150878A1 |
A process for efficient production of sugar 1-boranophosphates represented by general formula (I): (I) (wherein R1 and R2 are each alkyl; and R∼O- is a sugar compound residue), which comprise the step of reacting a sugar compound repre...
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WO/2009/138601A2 |
The invention relates to the use of mannose-6-phosphate (M6P) and of certain derivatives thereof for controlling angiogenesis and ligament regeneration and/or cartilage reconstruction. The MP6 and certain derivatives thereof can particul...
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WO/2009/140345A2 |
A method of improving the stability of sucralose crystals includes washing the sucralose crystals with a solution of a buffer in a solvent, and subsequently drying the sucralose crystals. The method may be used in a sucralose manufacturi...
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WO/2009/113322A1 |
Provided is a photodissociable protective group which can be eliminated from the protection site under mild conditions with light irradiation. Specifically, a method is provided which comprises using the photodissociable protective group...
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WO/2009/102736A1 |
The invention disclosed in this document is related to the field of pesticides and their use in controlling pests. A compound having the following structure is disclosed.
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WO/2009/098400A1 |
The invention relates to a chemical compound of the disaccharide type of the following general formula (A): where, Z = O or S; X1 = azido or NHCOR3 where R3 = 1 -5 c alkyl or aryl, X2 = benzyl, H or sulfonate, X3 = -CH2φ, -CHφ forming ...
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WO/2009/096433A1 |
The invention provides a process for the production of polyoxyethylene sorbitan fatty acid esters which are little bitter just after the production and the bitterness of which little increases even after the lapse of time. A process for ...
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WO/2009/087676A1 |
The present invention relates to an improved process for the preparation of 2, 3, 6, 3', 4'- Penta-O-acetylsucrose (6-PAS) (V) from sucrose. Formula (V)
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WO/2009/078030A1 |
The present invention describes a fat substitute formed by the conjugation of fructo-oligosaccharides with omega fatty acids. The fat substitute of the present invention imparts heat stability to the omega fatty acid, shows synergy in th...
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WO/2009/044886A1 |
The invention aims to provide a process for producing 1,2,3-tri-O-acetyl-5-deoxyribofuranose by an industrially suitable means. The invention provides a process for the production of 1,2,3-tri-O-acetyl-5-deoxyribofuranse which comprises ...
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WO/2009/038978A2 |
Steviol glycoside isomers are provided having the formula (II): wherein R1may be hydrogen, 1-β-D-glucopyranosyl, or 2-(1-β-D-glucopyranosyl)-1-β-D- glucopyranosyl, and R2 may be hydrogen, 1-β-D-glucopyranosyl, 2-(1-β-D-glucopyranosy...
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WO/2009/035503A1 |
A process for preparing a sucrose-6-ester, a key intermediate to sucralose. The process contains (a) reacting sucrose with a di(hydrocarbyl)tin oxide or a 1,3-diacyloxy-1,1,3,3-tetra(hydrocarbyl)distannoxane in the presence of a secondar...
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WO/2009/035528A2 |
The invention provides functionalized monosaccharides and disaccharides suitable for use in synthesizing a lipid A derivative, as well as methods for synthesizing and using a synthetic lipid A derivative.
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WO/2009/031464A1 |
The invention aims at providing a cellulose ester film excellent in planarity and haze; an optical film which is reduced in the unevenness of coating in forming a hard coat layer on the cellulose ester film and which is improved in unifo...
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WO/2008/134830A1 |
A method to obtain monophosphoryl Lipid A from Bordetella pertussis (BpMPLA) as a by-product of cellular pertussis vaccine production, for use in immunostimulatory applications such as a vaccine adjuvant, and more particularly, a method ...
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WO/2008/136266A1 |
It is possible to provide an optical compensation film which has an excellent visibility (light leak, hue irregularities, front contrast) and can simultaneously satisfy retardation and a wavelength dispersion property. Moreover, it is po...
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WO/2008/132541A2 |
The present invention concerns a compound of general formula (I) wherein: R1, R2 and R3 mean, independently from the others, an hydrogen atom or an optionally substituted lower alkyl, a (C1-C7) acyI group or a benzyl, R4 is an optionally...
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WO/2008/131047A2 |
The invention relates to plasminogen activator- 1 (PAl-1I) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such c...
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WO/2008/127381A2 |
This disclosure provides improved derivatives of artemisinin; pharamaceutical compositions containing these compounds; methods for preparing these compounds and compositions; methods of using these compounds and compositions for preventi...
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WO/2008/116359A1 |
The present invention discloses a method for preparing sucrose-6-ester, which comprises that acetonitrile/ethanol/hydrogen chloride or acetonitrile/methanol/hydrogen chloride were firstly mixed by the molar ratio of 1: (0.9-1.1): (0.9-1....
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WO2008052077B1 |
One embodiment of the present inventionis a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO4 2-
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WO/2008/092405A1 |
The invention discloses a method for synthesizing 1,2,3-tri-O-acetyl-5-deoxy-D -ribose, an intermediate of nucleotide compounds: using inosine as starting material and firstly reacting inosine with iodine in an organic solvent to obtain ...
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WO/2008/090631A1 |
It is intended to provide a fucoidan-derived low molecular compound with a specified structure and function in which problems regarding absorption property, antigenicity, homogeneity, anti-coagulant activity and the like of fucoidan, whi...
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WO/2008/090425A1 |
The present invention relates to compounds of the following general formula (I) their process of preparation and their use in the treatment or the prophylaxis of tuberculosis.
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WO/2008/084197A1 |
The present application discloses a process for the synthesis of a sucrose-6-ester comprising: (a) forming a first reaction mixture comprising sucrose, a polar aprotic solvent, and an organotin-based acylation promoter; (b) removal of wa...
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WO/2008/081270A2 |
There is described a process for the preparation of 3,6-di-O-acetyl-D-glycals by C4->C6 acyl migration by treatment of corresponding 3,4-di-O-acetyl-D-glycals with a buffer at pH of from 8.6 to 9.5. The starting 3,4-di-O-acetyl-D-glycals...
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WO/2008/071693A2 |
Novel sugar phosphonates are disclosed containing a sugar moiety selected from selected polysaccharides, saccharides which are free of aldehyde and keto groups, sugar alcohols and monosaccharides and a phosphonate moiety selected from an...
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WO/2008/065370A2 |
We describe glycosyltransferase polypeptides that modify sesquiterpenoids and including pharmaceutical compositions comprising glycosylated sesquiterpenoids; methods to treat diseases, in particular cancer, bacterial and fungal infection...
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WO/2008/037288A1 |
A new class of saccharide esters is disclosed consisting of saccharide esters of polyhydroxyalkanoic acids and polyhydroxyalkenoic acids, saccharide esters of hydroxy- alkanoyloxy- and polyhydroxyalkanoyloxy-substituted alkyl carbamic ac...
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WO/2008/019784A2 |
Disclosed are novel avermectin derivatives of formula (I), wherein -C22R1-A-C23R2, R3, R4, and R5 have the meanings indicated in the description, methods for producing said substances, the use thereof for controlling animal pests, novel ...
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WO2007099557B1 |
A process for controlling the emission of gaseous by-products in the preparation of a Vilsmeier reagent, and its use as a chlorinating reagent in the production of high intensity sweeteners, such as trichlorogalactosucrose, from partiall...
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WO/2008/006251A1 |
A preparation process of 6-O-benzoyl sucralose tetra-acetate, including the following steps: (1) sucrose as a starting material is regioselectively 6-O-benzoylated in DMF, using tri-carboxyl borate as complexing agent to produce 6-O-benz...
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WO/2008/003444A1 |
The invention relates to fatty acid esters of polyols or sulphonated fatty acid esters or sulphonated fatty acid amides having at least one Y group, wherein Y represents CF3-(CH2)a-O-, SF5-, CF3-(CH2)a- S-, CF3CF2S-, [CF3-(CH2)a]2N- or [...
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WO2006117799B1 |
This invention comprises novel application of a molecular separation process, including one or more of a membrane separation/filtration process comprising reverse osmosis, micro filtration, nanofiltration ultrafiltration and perevaporati...
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WO/2008/000920A1 |
The invention relates to a D-glucopyranose 1-[3,5-bis(1,1-dimethyl-ethyl)-4-hydroxybenzoate compound defined by formula (I). It applies in particular to the preparation and the use of this compound and of its derivatives for the preparat...
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WO/2007/144316A2 |
The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making novel engineered meningococcal strains wh...
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WO/2007/144317A2 |
The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making novel engineered meningococcal strains wh...
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WO/2007/135086A1 |
A process is described for the preparation of N-Acetyl-D-mannosamine monohydrate of formula (I) a specific intermediate in the synthesis of N-Acetyl-neuraminic acid, that is an important starting product for the synthesis of various phar...
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WO/2007/125328A1 |
A process for the production of an ester of a non-reducing sugar or sugar derivative comprises reacting the non-reducing sugar or sugar derivative with a triglyceride of a fatty acid or a fatty acid ester of a monohydric alcohol in air, ...
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WO/2007/125543A1 |
An improved process of production of a chlorinated sugar is described comprising chlorination of a partially protected sugar, wherein quenching as well as neutralization of chlorinated reaction mass is carried out concurrently and contin...
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WO/2007/119717A1 |
Disclosed is an industrially advantageous process for producing a 2,3,4,6-tetra-O-acyl-D-aldohexopyranose derivative and a 2,3,4,6-tetra-O-acyl-5-thio-D-aldohexopyranose derivative in a safe manner and with high yield. A 2,3,4,6-tetra-O-...
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WO/2007/115808A1 |
Esters of arginine (L- and/or D- enantiomers) with D-galactose useful as prodrugs are described, possessing a high capacity for penetrating cell membranes and the blood-brain barrier. The esters of the invention, once absorbed, gradually...
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WO/2007/104242A1 |
The invention has disclosed 1,2,3-trihydroxy benzene and its derivatives or pharmaceutically acceptable salts of formula I for zinc ion metal-protease inhibition. These compounds are used for selective depressants of zinc ion metal-prote...
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