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WO/2001/094367A1 |
Substances which hinder human $g(a)-amylase potently and are effective in the prevention and treatment of hyperglycemia such as diabetes and diseases due thereto; and $g(a)-amylase inhibitors and preventive or therapeutic drugs for hyper...
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WO/2001/094356A1 |
An aqueous solution containing an alkali metal salt of a partial alkyl ester of phosphoric acid wherein the alkyl groups may be each linear or branched and have 16 to 22 carbon atoms on the average, the degree of phosphorylation is 0.6 t...
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WO/2001/090299A2 |
A novel saccharide which is free from carbon-carbon double bond and carbonyl, is represented by the molecular formula: C6H10O5, and exhibits in high-performance liquid chromatography a retention time of 11.0 ± 0.2 min as determined by u...
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WO/2001/090338A1 |
$g(a)-Isomaltosyltransferase capable of forming a cyclic tetrasaccharide having a cyclo { - 6} -$g(a)-D-glucopyranosyl- (1 - 3) -$g(a)-D-glucopyranosyl- (1 - 6) -$g(a)-D-glucopyranosyl- ( 1 - 3) -a-D-glucopyranosyl- ( 1 - ) structure via...
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WO/2001/085745A1 |
Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or...
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WO/2001/083564A1 |
Soluble amphiphilic macrocycle analogues having lipophilic groups attached to one side of the units making up the macrocycle and hydrophilic groups attached to the other side. These amphiphilic macrocyclic derivatives have the ability to...
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WO/2001/072698A1 |
The present invention relates to an optically active (2S,3R)-4-cyanobutan-1,2,3-triol derivative, a process for preparing same, and a process for preparing 2-deoxy-L-ribose from same.
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WO/2001/061353A1 |
An array having a target substance immobilized at 2 or more points in a pre-determined region on a solid phase per cm?2¿ of a solid phase base, wherein the target substance is immobilized at 2 or more points at different concentrations ...
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WO/2001/053306A2 |
The invention relates to the methods of manufacturing five-carbon sugars and sugar alcohols as well as other compounds derived from pentose-phosphate pathway from readily available substrates such a hexoses using metabolically engineered...
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WO/2001/044450A1 |
The present invention provides a vector encoding trehalose-6-phosphate synthase (otsA)/trehalose-6-phosphate phosphatase (otsB) fusion protein and methods by which the fusion protein may be expressed in mammalian cells to provide enhance...
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WO/2001/044489A2 |
The invention relates to methods for the hydrolysis of galactomannan compounds and various uses of the hydrolysate.
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WO/2001/042262A2 |
The present invention relates to compounds of the formula (I), wherein R is independently SO¿3??-¿ or CH¿3?; the spacer is a flexible spacer of a length of 13-25 atoms; the charge of the pentasaccharide residue is compensated by posit...
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WO/2001/042263A2 |
The invention relates to an oligosaccharide mixture based on oligosaccharides produced from one or several animal milks and which are composed of two or more monosaccharide units. Said oligosaccharide mixture is characterized in that it ...
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WO/2001/037843A1 |
The invention provides methods of preventing and treating pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin and related conditions in a patient by administering to the patient antiendotoxin compounds by inhalat...
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WO/2001/038338A1 |
The invention concerns oligomannosides produced by synthesis, homologous with oligomannosides of the wall of an infectious or pathogenic organism, or a derivative thereof, as a yeast, a fungus, a virus, a bacterium. The invention also co...
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WO/2001/030731A1 |
The invention concerns a method for preparing a heat-stable and alkali-resistant, non-crystallizable polyol syrup, comprising a step which consists in hydrogenating a sugar syrup and a step which consists in caramelizing the hydrogenated...
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WO/2001/023397A1 |
This invention relates to a method for the preparation of the phytoalexin elicitor hexasaccharide that can be used as pesticide. 1,2:5,6-Di-O-isopropylidene-glucoturanose is used as the glycosyl acceptor and 1,3-$g(b)-linked disaccharide...
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WO/2001/023398A1 |
The present invention relates to a process for the preparation of oligosaccharides or oligosaccharide containing compounds, especially N-acetyl-chitooligosaccharides having a fucosylated monosaccharide. The invention also relates to nove...
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WO/2001/020969A2 |
Ribose administered before exercise reduces or prevents exercise-induced muscle cramping and soreness. Ribose taken both before and immediately after exercise further reduces or prevents exercise-induced muscle cramping and soreness.
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WO/2001/019401A1 |
The invention relates to a method for producing an improved tablet whereby said constituents are agglomerated. The invention also relates to a tablet produced according to the above method.
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WO/2001/019960A1 |
Chimeric carbohydrates produced by recombinant microorganism carrying exogenous glycosyl transferases act with or without exogenous enzymes required for synthesis or nucleotide synthesis precursors. These recombinant microorganism can be...
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WO/2001/016145A1 |
Immunopotentiating compositions containing lactose/fructose oligosaccharides as the active ingredient and compositions accelerating the production of interferon-$g(g), in particular, in the form of foods. Administration or intake of thes...
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WO/2001/014394A2 |
Disclosed are derivatized malto-oligosaccharides and methods for the preparation thereof. In accordance with the disclosed invention, a malto-oligosaccharide is hydrogenated to thereby obtain a hydrogenated malto-oligosaccharide, and the...
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WO/2001/004330A1 |
A method for the prdouctin of plants with an increased tocipherol and tocotrienol content by overexpression of a gene coding for 2-methyl-6-phytylhydroquinone-methyltransferase.
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WO/2001/004341A1 |
The invention concerns the production by microbiological process of oligopolysaccharides of biological interest. More particularly, the invention concerns a method for synthesizing in vivo oligopolysaccharides by internalization of an ex...
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WO/2000/076525A1 |
Anticancer emulsions characterized by containing: (A) an anthracycline compound; (B) one or more saccharides in an amount of at least 10 w/v% in the aqueous phase; and (C) fats and/or a surfactant. The emulsion stability of the anticance...
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WO/2000/070060A1 |
Compositions and methods for making complex carbohydrates in a bacterial production cell are disclosed. The complex carbohydrates that can be made include oligosaccharides and polysaccharides of bacterial or mammalian origin.
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WO/2000/064451A1 |
A method for enhancing the blood factors of a mammal comprising administering to a mammal in need of such enhancement an efficacious amount of tagatose.
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WO/2000/061592A1 |
The invention concerns a method for the synthesis of monosulphate of 4 or 6 disaccharides from a disaccharide precursor protected on its hydroxyl functions other than 4 or 6 galactose comprising steps of sulphating and deprotecting of th...
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WO/2000/055349A1 |
A novel trehalose derivative represented by formula (I). This compound is useful as a trehalose inhibitor and a stabilizer in freeze-drying proteins.
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WO/2000/050621A2 |
A process for producing aldehydes, and/or carboxylic acids is described, in which a primary alcohol, especially a carbohydrate, is oxidised using a catalytic amount of a nitrosonium compound obtained by oxidising a nitroxyl compound in t...
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WO/2000/050388A1 |
A process for producing nitrosonium ions is described, in which a nitroxyl compound such as TEMPO is oxidised using an oxidising agent in the presence of a complex of a transition metal such as Mn, Fe, Cu, and a complexing agent such as ...
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WO/2000/050434A1 |
Malto-oligosaccharide derivatives represented by general formula (1); hydrates or physiologically acceptable salts thereof; and $g(a)-amylase inhibitors or preventive or therapeutic agents for hyperglycemia including diabetes, containing...
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WO/2000/046238A1 |
A solid phase synthetic method is disclosed in which the usual solid phase synthetic steps are carried out and the spent solid phase support is reacted to form a volatilizable compound upon cleavage of the reaction product from the solid...
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WO/2000/043018A1 |
Medicinal compositions for treating or preventing diabetes, rheumatoid, diseases wherein inflammation should be inhibited, diseases wherein $g(a)-glycosidase should be inhibited, diseases wherein the synthesis of prostaglandin should be ...
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WO/2000/043407A1 |
Compounds represented by general formula (I) wherein X represents OH or OSO¿3?H; and R represents a substituent other than OH which allows, after leaving, the induction of unsaturated bonds into the 3- and 4-positions of 3,6-anhydrogala...
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WO/2000/039141A1 |
The application relates to the design and synthesis of novel hexasaccharides of general formula (I), wherein: each R is independently selected from hydrogen, an alkyl or substituted alkyl group, an acyl or substituted acyl group, a phosp...
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WO/2000/039139A1 |
Conjugates of saccharide and an acetamidino- or guanidino- compounds of formula (I), wherein A is CH¿3? or NH¿2?; X is a linear or branched C¿1?-C¿8? alkyl chain optionally containing hydroxy, amino and/or oxo groups; n is an integer...
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WO2000018777A9 |
The invention is directed to a method for synthesizing C-glycosides of ulosonic acids, as well as intermediates thereof and C-glycosides prepared by this method.
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WO/2000/036138A1 |
A method is described for high-sensitivity screening for the presence of inhibition of at least one enzyme in the biosynthetic pathway to terpenoids via 1-deoxy-D-xylulose 5-phosphate in plants by incubating an aqueous suspension of plas...
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WO/2000/030614A1 |
The invention provides a process for crystallization of amorphous and/or meta-stable crystalline regions of preformed particles by treating the particles with a supercritical or subcritical fluid containing an anti-solvent and a solvent....
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WO/2000/029417A1 |
A process of preparing a L-ribose fraction having greater than 97% purity starting from an aqueous solution of L-arabinose is provided by utilizing an epimerization reaction conducted in the presence of a Mo compound and eluting the prod...
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WO/2000/029418A2 |
Inhibitors of glycosidases and glycosyltransferases, methods for their preparation and their identification are described.
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WO/2000/012524A1 |
Oligomers are prepared substantially free of error sequences by sequencially adding monomers to a growing chain bound to a support through a first selectably cleavable linkage, a first capture moiety and a second selectably cleavable lin...
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WO/2000/009527A1 |
The reactivity of a number of $i(p)-methylphenyl thioglycoside (STol) donors which are either fully protected or have one hydroxyl group exposed has been quantitatively determined by HPLC in conjunction with the development of a broadly ...
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WO/2000/008467A2 |
Compounds which bind to toxins associated with enteric bacterial infection, compositions including the compounds, methods for the neutralization of toxins in a patient, and methods for the diagnosis of bacterial and viral infections are ...
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WO/2000/006115A1 |
Sialyl oligosaccharides and derivatives useful for regulating inflammatory responses, and treating related disorders and conditions, and/or improving the texture or appearance of the skin, as well as topical pharmaceutical and cosmetic c...
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WO/2000/003745A2 |
The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical charac...
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WO/2000/001710A2 |
The present invention relates to a product which is obtained from the reaction of formaldehyde with a carbohydrate, a carbohydrate derivative or a mixture of two or more of these compounds.
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WO/1999/065712A2 |
A new class of synthetic glycosulfopeptides (GSPs) which have one or more sulfated tyrosine residues and a glycan linked to the peptide, the glycan preferably including a sialyl Lewis?x¿ group or a sialyl Lewis?a¿ group. In a preferred...
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