| Document |
Document Title |
|
JP4370162B2 |
The present invention relates to novel solid-phase processes for the production of radiolabelled tracers, in particular for the production of <18>F-labelled compounds which may be suitable for use as Positron Emission Tomography (PET) ra...
|
|
JP4373671B2 |
The present invention provides a substance which strongly inhibits human alpha -amylase and is effective for the prevention and treatment of hyperglycemia, for example, diabetes and the diseases caused thereby, and an alpha -amylase inhi...
|
|
JP4373634B2 |
|
|
JP4367798B2 |
Compositions containing a glycosylated drug derivative of formula (I) and/or its salts, a carrier and optionally divalent ions, is new. G-Y-(C(=Y)-X)p-W(R)n-X-C(=Y)-A (I) Also claimed is the production of the preparation by processing th...
|
|
JP2009538386A |
Preparations of low molecular weight heparins (LMWHs) having improved properties, e.g., properties that provide a clinical advantage, are provided herein. Methods of making and using such preparations as well as methods of analyzing star...
|
|
JP2009538293A |
This invention comprises an improved process for recovery and purification of DMF from an aqueous process stream containing DMF with or without inorganic impurities, particularly from process stream of a process of manufacture of the hig...
|
|
JP4347042B2 |
New crystalline trisaccharides or higher saccharides.
|
|
JP4347488B2 |
A process for the addition of an azide function to an organic compound in which process a mixture is prepared by adding an epoxide-derivative of the organic compound and an alkali metal azide salt to a solvent is described. The mixture i...
|
|
JP4342586B2 |
A process for production of 18 F-FDG is provided, which can produce 18 F-FDG in a high and stable yield of synthesis. A process for production of a compound labeled with radioactive fluorine comprises the steps of: preparing a reaction s...
|
|
JP2009533345A |
Processes for the synthesis of lipochitooligosaccharides were developed. A fully acylated oligoglucosamine precursor is prepared and reacted with a glucosamine monomer that has an amine protecting phthaloyl group. With removal of the pht...
|
|
JP2009533322A |
Lactosamine derivatives and related methods suitable for the preparation, including large-scale production, of N-acetyllactosamine, lactosamine, numerous lactosamine salts and a number of lactosamine-containing oligosaccharides are provi...
|
|
JP2009531301A |
Methods of treating glioblastoma and pancreatic cancer are provided by the administration of a therapeutically effective amount of a hexose compound to a subject in need thereof The subject invention includes methods of treating brain an...
|
|
JP4323139B2 |
Production of sugar chain asparagine derivatives comprises: (a) obtaining a mixture of sugar chain asparagine derivatives by introducing a fat-soluble protecting group into a mixture of at least one sugar chain asparagine derivative; (b)...
|
|
JP2009528342A |
Preparation of chlorinating reagent or chlorination reaction itself for use in a reaction such as production of high intensity sweetener trichlorogalactosucrose (TGS) from partially protected sucrose, comprising reaction of dimethylforma...
|
|
JP4307072B2 |
The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the pathological conditions originating from metabolic...
|
|
JP2009526031A |
A process for the preparation of a thiosaccharide represented by Saccharide-S-H wherein Saccharide comprises at least 4 sugar units, comprises subjecting a corresponding compound of the formula (P)Saccharide-S-(P) wherein (P) represents ...
|
|
JP4297697B2 |
|
|
JP4287502B2 |
A method of producing a radioactive-fluorine-labeled compound has a step of heating in a reaction vessel a mixture containing [ 18 F] fluoride ions, a phase transfer catalyst, potassium ions, and water to evaporate water from the mixture...
|
|
JP4290231B2 |
|
|
JP4285997B2 |
The present invention has disclosed a use of N-acetyl-D-glucosamine in the preparation of a medicine for preventing and treating the sexual disfunction. The preparation taken N-acetyl-D-glucosamine as a main active component has been use...
|
|
JP4273116B2 |
The present invention provides a therapeutic agent for nerve damages such as those caused by spinal cord injury or nerve trauma, which comprises, as an active ingredient, a low-molecular-weight saccharide composed of at least glucuronic ...
|
|
JP4255113B2 |
To provide a catalyst oxidizing and desulfating a sulfated saccharide having a glucosamine skeleton in a large amount on an industrial scale at a low cost. The catalyst consists essentially of the following (A) or a protein having functi...
|
|
JP4249853B2 |
The present invention provides a skin care agent comprising N-acetylglucosamine as an active ingredient. The skin care agent is preferably in the form of tablets, capsules, powder such as dust or granules, liquid or paste. The skin care ...
|
|
JP2009513527A |
The invention pertains to steroid modified solatrioses and the synthesis thereof as well as to intermediate compounds useful for the synthesis of the steroid modified solatrioses.
|
|
JP4241377B2 |
The invention relates to a process for isolating a lectin composition, in particular comprising the mannose-binding lectin (MBL), suitable for using recombinantly produced lectins as starting material, as well as methods for enriching a ...
|
|
JP2009509925A |
This invention relates to a process for selective capture, isolation and purification of chlorinated sucrose compounds, including chlorinated sucrose, their precursors and derivatives, including trichlorogalactosucrose (TGS), directly fr...
|
|
JP2009508519A |
A process of production of trichlorogalactosucrose is described in which deacylation of sucrose-6-ester is achieved by subjecting the reaction mixture after chlorination, neutralization and adjustment of pH to 6.5 to 7 to deacylation by ...
|
|
JP2009046486A |
To produce analogues or derivatives of quercetin, which have enhanced aqueous solubility and which are especially suitable for use in pharmaceutical formulations, acting as prodrugs biodegradable to release quercetin in the body after ad...
|
|
JP2009029770A |
To provide a new cell proliferation inhibitor having enhanced activity.The cell proliferation inhibitor contains a compound represented by the formula of the Figure [wherein R1 is an acyloxy group which may be substituted or -NHR (wherei...
|
|
JP2009023923A |
To provide a simple and easy method for producing an organic acid salt of amphipathic glucosamine, chitosan oligosaccharide and heterooligosaccharide, and to provide the use thereof.The method for producing the organic acid salt includes...
|
|
JP2009503061A |
Disclosed herein is a transglutaminase inhibitor comprising glucosamine or a derivative thereof. Exhibiting potent inhibitory activity against transglutaminase, the overexpression of which is responsible for the etiology of various disea...
|
|
JP4209617B2 |
|
|
JP2008308414A |
To provide a remedy for treating temporomandibular joint arthrosis for which effective treating methods have been a little.This temporomandibular joint arthrosis remedy is characterized by containing glucosamine. The temporomandibular jo...
|
|
JP4201360B2 |
The invention relates to carbohydrate derivatives having the formula I, wherein R<1> is H or CH2OSO3<->; R<2> and R<3> are independently H, (1-6C)alkyl or SO3<->; R<4> is OSO3<->or NHSO3<->; n is 0 or 1; p is 1 or 2; or a pharmaceuticall...
|
|
JP2008542199A |
A process is described wherein after formation of first crop of Vilsmeier-Haack reagent by reacting Phosphorus Pentachloride with N,N-dimethylformamide to form a first crop of Vilsmeier reagent as insoluble crystals, a by-product of this...
|
|
JP4178584B2 |
|
|
JP4179567B2 |
A method for producing an N-acetyllactosamine oligosaccharide, comprising the steps of: adjusting a sulfate group content of keratan sulfate; allowing an enzyme having an ability to cleave a glycosidic linkage of keratan sulfate to act o...
|
|
JP4174702B2 |
The present invention offers a novel asymmetric double-headed lipid capable of forming a stable, nanometer scale micro-tubular aggregated material of containing a sugar and a carboxylic acid at each end. The present invention is an a...
|
|
JP4177471B2 |
A method of preparing a therapeutically active crystalline form of glucosamine sulphate which is stable at ambient temperature and humidity and corresponds to the empirical formula: (I) in which M represents a metal selected from the gro...
|
|
JP4169689B2 |
The present invention is related to compounds comprising mannitol or glucitol derivatives which may be used to build up oligomeric compounds. The invention is further related to uses of these oligomeric compounds for hybridization and as...
|
|
JP2008214256A |
To provide a method for producing a double-headed type glycoside compound that is applicable in a wide range of uses and advantageous in terms of cost and to provide a new double-headed type glycoside compound that crosslinks, flocculate...
|
|
JP2008185373A |
To provide a method which enables the simple analyzation of a composition containing an acidic oligosaccharide such as an oligosaccharide containing fucose obtained by hydrolyzing fucoidin, especially a disaccharide or above oligosacchar...
|
|
JP4132297B2 |
|
|
JP2008530226A |
The invention describes novel organic nitric oxide donor salts of a antimicrobial compounds, and novel compositions and kits comprising at least one organic nitric oxide donor salt of an antimicrobial compound, and, optionally, at least ...
|
|
JP4119890B2 |
Sulfated fucan lyase capable of decomposing sulfated fucan derived from sea cucumber; a process for producing the enzyme; a low molecular compound obtained by causing the enzyme to act on sulfated fucan; a process for producing the same;...
|
|
JP4115066B2 |
|
|
JP4113258B2 |
Process for preparing isotopically labelled compounds comprises: (a) preparation of the labelling agent; (b) labelling of a precursor in the form of a protected substrate; (c) pre-purification; (d) deprotection; and (e) formation of fina...
|
|
JP4109989B2 |
It is intended to provide a process whereby a substance positive in Elson-Morgan reaction can be industrially, economically, easily and stably produced; a process for producing a composition containing a substance positive in Elson-Morga...
|
|
JP4110243B2 |
|
|
JPWO2006070862A1 |
The present invention provides a production method capable of industrially and efficiently producing 5-deoxy-L-arabinose, which is important as a raw material for producing sapropterin useful as a therapeutic agent for atypical hyperphen...
|
