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JP4672994B2 |
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JP4632545B2 |
A compound of the formula (I): and a compound of the formula (V): as well as a compound of the formula (X): which are each a novel siastatin B derivative having a potent inhibitory activity against a glycosidase, are now synthesized by n...
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JPWO2009044886A1 |
An object of the present invention is to provide a method for producing 1,2,3-tri-O-acetyl-5-deoxyribofuranose by an industrially suitable method. According to the present invention, Eq. (1) or Eq. (2):(In the formula, P1And P2Independen...
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JP4630549B2 |
Method for preparing a compound comprising protonated glucosamine and Cl-, Na+ and SO42- ions, in which (a) glucosamine hydrochloride and a stoichiometric excess of sodium sulphate are placed in water, (b) the mixture obtained from the p...
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JP4623763B2 |
A process for separating, in the liquid phase, a reaction mixture which comprises a first chlorinated sucrose and at least one additional component selected from the group consisting of at least one other chlorinated sucrose different fr...
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JP2011503027A |
A 1,2-dideoxy-1,2-diamino oligosaccharide or polysaccharide in its free base, salt or metal-complex form as shown in General Formula 1 and derivative thereof is described. R1, R2 and R3 are each independently selected from the group cons...
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JP4619659B2 |
The present invention relates to novel methods for stabilizing aqueous deacylation, via use of buffers in the production of sucralose. The present invention provides a process for producing sucralose from an acyl-sucralose compound where...
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JP2010285446A |
To provide processes for producing alkylamino glucosaminide phosphate compounds and disaccharide compounds functioning as immunoeffectors or adjuvants intended for vaccines and the like comprising various novel intermediates and intermed...
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JP2010285371A |
To provide an industrially easy method for inexpensively producing a long-chain (saturated/unsaturated) fatty acid derivative of β-D-glucopyranosylamine.The long-chain (saturated/unsaturated) fatty acid derivative of the β-D-glucopyran...
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JP2010285372A |
To provide a method for industrially inexpensively purifying a long-chain (saturated/unsaturated) fatty acid derivative of β-D-glucopyranosylamine without using a high-cost purification method such as silica gel column chromatography.Th...
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JP4601107B2 |
To obtain a nutrition composition or an antiviral agent containing a new lactone derivative of an N-acetylneuraminic acid compound not to be hydrolyzed by sialidase in vivo. This composition such as powdered milk for infant rearing, diet...
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JP4599505B2 |
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JP4598956B2 |
This invention relates to (2R,3S,4R,5R)-2-amino-5-methylpiperidine-3,4-diol or a (2S,3S,4R,5R)-2-N-substituted-2-amino-5-methylpiperidine-3,4
-diol represented by the general formula (I): wherein R<1> and R<2> each are a hydrogen atom, o...
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JP4589865B2 |
The present invention relates to An N-acetylglucosamine derivative represented by the following formula (1), and a hyaluronic acid production promoting agent containing the same and a skin external preparation containing the same: wherei...
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JP4585172B2 |
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JP4577478B2 |
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JP4567887B2 |
The present invention relates to a method and materials for producing glucosamine by fermentation of a genetically modified microorganism. Included in the present invention are genetically modified microorganisms useful in the present me...
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JP4560637B2 |
The present invention provides an improved form of crystalline sucralose.
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JP4555466B2 |
Substituted tetrahydropyran derivatives, processes for their preparation, their use as a pharmaceutical or diagnostic, and pharmaceutical comprising them. The invention relates to compounds of the formula Iin which the radicals R<1>, R2,...
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JP2010531295A |
Methods and devices for a fully automated synthesis of radioactive compounds for imaging, such as by positron emission tomography (PET), in a fast, efficient and compact manner are disclosed. In particular, the various embodiments of the...
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JP2010193858A |
To provide a preparation process of a chitin decomposition product having an excellent productivity with which a chitin decomposition product can effectively be obtained through an enzyme reaction using, as a base material, a low-crystal...
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JP2010529021A |
The invention relates to compositions and methods for treating kidney and muscle dysfunction that involves use of therapeutic amounts of N-acetyl mannosamine.
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JP4527104B2 |
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JP2010166934A |
To provide a method and materials for producing glucosamine by fermentation of a genetically modified microorganism.Included in the present invention are genetically modified microorganisms useful in the present method for producing gluc...
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JP4519774B2 |
An on-column process by which various radioactive-fluorine-labeled compounds can be obtained in a high yield. The process comprises a step in which [ 18 O] water containing [ 18 F] fluoride ions is introduced into a column packed with an...
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JP2010526055A |
An isolated polysaccharide has the structure [-beta(1,3)-D-GaIpNAc-beta(1,4)-D-Glcp-]n. The polysaccharide may be from a Bifidobacterium strain NCIMB 41003. The polysaccharide exhibits immunomodulatory activity.
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JP4500008B2 |
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JP4496375B2 |
The present invention has an object of revealing an epidermis regeneration effect of various chitin derivatives and providing an agent for therapy or treatment for wound which can be clinically used effectively. According to the present ...
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JP4495598B2 |
An asparagine-linked oligosaccharide of the formula (1) given below having undeca- to tri-saccharides wherein R1 and R2 are each a hydrogen atom or a group of the formulae (2) to (6) disclosed in the specification and may be the same or ...
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JP4466972B2 |
It is intended to provide an N-acetylglucosamine tablet, with which N-acetylglucosamine can be taken in an amount at which a physiological activity can be expected in a small number of tablets, and which has an excellent disintegrating p...
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JP4469273B2 |
The invention provides MRI detectable species of formula (I) Dp-Sn-Nm wherein D is a MRI detectable moiety S is a spacer N is a molecule of a nutrient or pseudo-nutrient n is 0 or an integer m is an integer and p is an integer. These...
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JP2010516665A |
There is provided a method for the production of sucralose from a feed stream resulting from the chlorination of a sucrose-6-acylate in a reaction vehicle, said feed stream comprising a sucralose-6-acylate, the reaction vehicle, and by-p...
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JP2010106041A |
To provide an 18F isotope-labeled FDG ([18F]2-Fluoro-2-Deoxy-D-glucose (hereinafter FDG)), radiopharmaceutical which is stable and safety to human body.The 18F isotope-labeled FDG radiopharmaceutical is stabilized against degradation in ...
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JP4450436B2 |
A process is claimed for producing sucralose, i.e. 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose of formula (I), from a feed mixt. contg. (a) 6-O-acyl-sucralose (II), (b) salt including alkali metal or alkaline earth metal chloride, (...
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JP4451132B2 |
The present invention relates to methods for producing novel spinosyn derivatives which are substituted with a 1-hydroxy-ethyl radical in the C-21 position and to novel spinosyn derivatives of this type per se and to their use for produc...
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JP2010059090A |
To provide a method for producing a glucosamine derivative which can more easily produce the glucosamine derivative.The method for producing glucosamine sulfate comprises dissolving glucosamine hydrochloride in water, followed by neutral...
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JP2010508285A |
In one embodiment of the invention a method to prepare sucralose-6 -acylate through chlorinating sucrose-6-acylate by BTC in the process of sucralose preparation is disclosed. In this embodiment a Vilsmeier reagent is firstly prepared be...
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JP2009539834T6 |
Imino or new processes for refining of amino sugar, such as D*1* deoxy galacto ノジリ mycin (DGJ). The process for refining of the sugar of several kilogram scale which uses chloride especially is indicated.
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JP2010506908A |
Disclosed herein is a novel use of glucosamine or a derivative thereof. A pharmaceutical composition for treating atopic dermatitis comprising glucosamine or a derivative thereof and a method of treating atopic dermatitis using the compo...
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JP4422392B2 |
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JP4410913B2 |
The present invention is a compound of general formula (I) or a pharmaceutically acceptable salt of,wherein W represents carbon chain from 9 to 17 which containing double bond or hydroxy group occasionally; X represents carbon chain from...
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JP4408960B2 |
The present invention relates to pseudoceramide derivatives represented by formula(I) or (II):wherein, each of R1 and R2 represents linear or branched alkyl group or alkenyl group having 6~22 carbon atoms; each of R3 and R4 represents hy...
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JP4405667B2 |
Compounds defined by the following general structure are disclosed: These compounds display pharmacological activities, including inhibition of tyrosine kinase activity and enhancement of the function and/or survival of trophic factor re...
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JP4401659B2 |
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JP4402878B2 |
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JP4403182B2 |
It is intended to provide an N-acetylglucosamine tablet, with which N-acetylglucosamine can be taken in an amount at which a physiological activity can be expected in a small number of tablets, and which has an excellent disintegrating p...
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JP4395653B2 |
Abstract of the Disclosure The present invention teaches novel compositions and methods for altering the sweetness delivery profile of 4,1',6'-trichloro-4,1',6'-trideoxygalactosucrose. This invention also teaches novel uses for compositi...
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JP4394960B2 |
The present invention is directed to compounds comprising a 2,3-diphenylquinoxaline moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containin...
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JP2009298803A |
To provide a sucralose crystal which has a stable configuration and is an artificial sweetener obtaining strong sweetness, and a method for producing it.The method for crystallization of sucralose from an aqueous solution comprises contr...
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JP2009542625A |
The present invention relates to an improved process for the preparation of Sucralose having purity of at least 99.6% comprising steps of (i) dissolving substantially impure Sucralose in water (ii) treating the solution obtained in step ...
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