Title:
１，１’−ジアダマンチルカルボン酸、このような化合物を含有する医薬及びその使用
Document Type and Number:
Japanese Patent JP5846909
Kind Code:
B2
Abstract:
The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases.
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Inventors:
Echult, Matthias
Hamilton, Bradford S
Himmelsbach, Frank
Hamilton, Bradford S
Himmelsbach, Frank
Application Number:
JP2011519184A
Publication Date:
January 20, 2016
Filing Date:
July 24, 2009
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
A61K31/19; C07C62/06; A61K31/215; A61K31/277; A61K31/397; A61K31/40; A61K31/4035; A61K31/404; A61K31/41; A61K31/4184; A61K31/423; A61K31/4245; A61K31/4462; A61K31/472; A61K31/495; A61K31/517; A61K31/5375; A61K31/55; A61P1/04; A61P1/18; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/00; A61P13/12; A61P17/02; A61P19/06; A61P25/00; A61P27/02; A61P43/00; C07C27/02; C07C51/09; C07C67/30; C07C69/753; C07C227/18; C07C229/50; C07C231/12; C07C233/52; C07C233/58; C07C233/60; C07C239/20; C07C261/04; C07C269/06; C07C271/24; C07D205/04; C07D207/16; C07D209/08; C07D209/44; C07D211/56; C07D213/64; C07D217/06; C07D223/16; C07D235/16; C07D239/74; C07D257/04; C07D263/56; C07D271/10; C07D295/18
Domestic Patent References:
| JP2006342093A | ||||
| JP2007269721A | ||||
| JP2007016223A | ||||
| JP2003057815A | ||||
| JP2006265224A | ||||
| JP2006206857A |
Foreign References:
| WO2001055063A1 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Fusayuki Saito
Hajime Tsukuni
Fusayuki Saito