A 2 sugar intermediate and a synthesizing method for the same - Zhejiang Hisun Pharmaceutical CO.,LTD.

Title:

A 2 sugar intermediate and a synthesizing method for the same

Document Type and Number:

Japanese Patent JP2016537349

Kind Code:

A

Abstract:

本発明は二糖中間体及びその合成方法に関し、化学製薬分野に属し、より具体的には、ヘパリン、ヘパリノイド化合物を化学合成するための重要中間体である二糖フラグメントの調製方法に関する。本発明は新規の二糖中間体及び三種類の二糖中間体の合成方法を開示し、即ち、活性化剤の存在下で式（４）の化合物と異なるアノマー炭素で保護されたグルコピラノースとを反応させて二糖中間体を得る。本発明の技術案は、合成原料が簡単に入手しやすく、反応条件が温和で、工業的生産に適する。

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Inventors:

Guo
Zhou Shun Haku
Cai Aomine
Mamoru
White Flower
Dragon Fly
Zhang month
Kure Autumn

Application Number:

JP2016530127A

Publication Date:

December 01, 2016

Filing Date:

April 28, 2014

Export Citation:

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Assignee:

Zhejiang Hisun Pharmaceutical CO.,LTD.

International Classes:

C07H3/04; C07H9/04

Domestic Patent References:

JP2013538874A

2013-10-17

Other References:

J. CARBOHYDRATE CHEMISTRY, vol. 4, no. 3, JPN6017023252, 1985, pages 293 - 321
COLLECT. CZECH. CHEM. COMMUN., vol. Vol.60, JPN6017023253, 1995, pages 311 - 323
CARBOHYDRATE RESEARCH, vol. Vol.149, JPN6017023254, 1986, pages 347 - 361
J. CARBOHYDRATE CHEMISTRY, vol. 12, no. 8, JPN6017023258, 1993, pages 1091 - 1103
ANGEW. CHEM. INT. ED., vol. Vol.48, JPN6017023262, 2009, pages 1900 - 1934

Attorney, Agent or Firm:

Shimano Public Interest

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