Title:
ヌクレオシド及びオリゴヌクレオチド含有ホウ素クラスター
Document Type and Number:
Japanese Patent JP4344959
Kind Code:
B2
Abstract:
Carboranyl-containing nucleosides and oligonucleotides are provided for use in boron neutron capture therapy (BNCT) and for other therapeutic and diagnostic purposes.
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Inventors:
Sinaji, Raymond, F
Kattan, Geraldine, F
Lesnikowski, Zubi New, Jay
Kattan, Geraldine, F
Lesnikowski, Zubi New, Jay
Application Number:
JP51577595A
Publication Date:
October 14, 2009
Filing Date:
December 02, 1994
Export Citation:
Assignee:
Emory, University
International Classes:
C07H23/00; A61K31/70; A61K31/7088; A61K31/7115; A61K41/00; A61K48/00; A61K49/00; A61K49/08; A61N5/00; A61P31/12; A61P35/00; C07H19/10; C07H19/20; C07H21/00; C12N9/12; C12N15/01; C12N15/10; C12N15/113; C12Q1/68; C12Q1/6816; C12Q1/6827; C12Q1/6886
Domestic Patent References:
| JP5163296A |
Other References:
Tjarks W. et. al., Synthesis and in vitro evaluation of boronated uridine and glucose derivatives for boron neutron capture therapy., J Med Chem, 1992年, Vol. 35, No. 9, 1628 - 1633
Lesnikowski Z. J. et.al., Carboranyl oligonucleotides. 1. Synthesis of thymidine(3′,5′)thymidine (o-carboran-l-ylmethyl)phosphonate, J Org Chm, 1993年11月19日, Vol.58, No.24, 6531-6534
Lesnikowski Z. J. et.al., Carboranyl oligonucleotides. 1. Synthesis of thymidine(3′,5′)thymidine (o-carboran-l-ylmethyl)phosphonate, J Org Chm, 1993年11月19日, Vol.58, No.24, 6531-6534
Attorney, Agent or Firm:
Akaoka Michio