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Title:
生体活性を有する骨芽細胞刺激表面を製造するための酵素的方法およびその利用
Document Type and Number:
Japanese Patent JP2007535320
Kind Code:
A
Abstract:
The invention relates to a method for producing bioactive surfaces by enzymatic modification of molecules or molecular aggregates, in particular, collagen, on surfaces of glass, metals, metallic oxides, plastics, biopolymers or other materials with an amorphous silicon dioxide (silica) or silicones in the cell culture, by tissue engineering or in medical implants, whereby a polypeptide is used for enzymatic modification, which contains a silicatein alpha or silicatein beta domain. The inventive method promotes the growth, activity and/or mineralization of cells/cell cultures.

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Inventors:
Schwertner, Heiko
Muller, Werner A. G.
Schrödel, Heinz, Tse.
Application Number:
JP2007509992A
Publication Date:
December 06, 2007
Filing Date:
May 02, 2005
Export Citation:
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Assignee:
Schwertner, Heiko
International Classes:
C12P3/00; A61L27/00; C12M1/00; C12N5/07; C12N5/071; C12N5/077; C12P9/00
Foreign References:
WO2000035993A12000-06-22
WO2002010420A22002-02-07
WO2004033679A12004-04-22
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Shinobu
Takuya Osugi



 
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