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Title:
HEDGEHOG SIGNAL INHIBITOR
Document Type and Number:
Japanese Patent JP2012211085
Kind Code:
A
Abstract:

To provide a hedgehog signal inhibitor or the like which contains as an effective ingredient, a condensed heterocyclic derivative or a pharmacologically acceptable salt thereof.

There is provided a hedgehog signal inhibitor or the like which contains as the effective ingredient, a condensed heterocyclic derivative represented by general formula (I) [wherein R1 is hydrogen or the like; R2 is hydrogen or the like; R3 is lower alkyl which may have a substituent, or the like; A is cycloalkyl which may have a substituent, or the like; B is 5- or 6-membered non-aromatic carbon ring which may have a substituent together with adjacent pyrrole ring of -C=C-, or the like; L1 is formula (i) or the like; L2 is formula (iii) (R4 is hydrogen or the like), formula (iv) or the like, and when L2 is formula (iv), Q does not exist, and when L2 is formula (iii), Q does not exist or is an oxygen atom], or a pharmacologically acceptable salt thereof.


Inventors:
SAWADA TAKASHI
FUJIWARA HIROAKI
Application Number:
JP2009187173A
Publication Date:
November 01, 2012
Filing Date:
August 12, 2009
Export Citation:
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Assignee:
KYOWA HAKKO KIRIN CO LTD
International Classes:
C07D209/42; A61K31/496; A61K31/497; A61K31/506; A61K31/5377; A61P17/06; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C07D209/52; C07D401/04; C07D403/04; C07D471/04; C07D491/052; C07D495/04