Title:
クロマトグラフィーシステムにおけるＵＶセル光路長の適合方法
Document Type and Number:
Japanese Patent JP7171058
Kind Code:
B2
Abstract:
The present invention relates to a method for determining operational status of a chromatography column (1; 39, 47, 59; 107, 109, 111, 113), comprising detecting a feed signal (21; 201) representative of the composition of a feed material provided to the inlet of the column; detecting the UV absorbance in the feed material, detecting an effluent signal (23; 203, 205, 207, 209) representative of the composition of the effluent from the column; and using the feed signal and the effluent signal to determine operational status of the column. The feed signal is generated using a first UV detector having a first UV cell pathlength operating at a first UV wavelength and in the effluent signal is generated using a second UV detector having a second UV cell pathlength operating at a second UV wavelength. The method further comprising determining a first threshold value based on the detected UV absorbance in the feed material, and selecting the first UV cell pathlength and/or first UV wavelength based on the first threshold value.
Inventors:
Hans Brohm
Michelle Bari
Hanno Elling
Linda Matiasion
Elena Skogler
Rebecca Himylevski
Michelle Bari
Hanno Elling
Linda Matiasion
Elena Skogler
Rebecca Himylevski
Application Number:
JP2019545366A
Publication Date:
November 15, 2022
Filing Date:
February 14, 2018
Export Citation:
Assignee:
Sitiva Sweden Activolag
International Classes:
G01N30/74; B01D15/00; B01D15/08; G01N30/42; G01N30/86
Domestic Patent References:
| JP2013518278A | ||||
| JP2016510981A | ||||
| JP2007113979A | ||||
| JP2000329757A |
Foreign References:
| US20120091063 |
Attorney, Agent or Firm:
Masato Iida
Choe Yun
Kenji Tanaka
Choe Yun
Kenji Tanaka
Previous Patent: Heteroaryl compounds and uses thereof
Next Patent: FRYING PAN MADE OF DUCTILE CAST IRON
Next Patent: FRYING PAN MADE OF DUCTILE CAST IRON