Title:
ヒト凝固因子VII変異型
Document Type and Number:
Japanese Patent JP4814359
Kind Code:
B2
Abstract:
The present invention relates to novel human coagulation Factor VIIa variants having coagulant activity as well as nucleic acid constructs encoding such variants, vectors and host cells comprising and expressing the nucleic acid, pharmaceutical compositions, uses and methods of treatment.
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Inventors:
Parson, Egon
Olsen, Olebirsted
Olsen, Olebirsted
Application Number:
JP2009148765A
Publication Date:
November 16, 2011
Filing Date:
June 23, 2009
Export Citation:
Assignee:
Novo Nordisk Health Care Akchen Gesell Shaft
International Classes:
A01H5/00; A01H1/00; C12N15/09; A01K67/00; A01K67/027; A61K38/00; A61K38/36; A61K38/48; A61P7/04; A61P41/00; C07K14/745; C12N5/10; C12N9/64; C12N15/12; C12P21/02; C07K; C12N
Domestic Patent References:
JP3500963A | ||||
JP2003521930A | ||||
JP2003531607A | ||||
JP2003531862A | ||||
JP2004505016A | ||||
JP8510746A |
Other References:
Proc.Natl.Acad.Sci.USA.,Vol.93,No.25(1996)p.14379-14384
J.Biol.Chem.,Vol.276,No.9(2001.Mar.)p.6616-6620
Biochemistry,Vol.38,No.34(1999)p.10940-10948
Biochemistry,Vol.34,No.27(1995)p.8701-8707
J.Biol.Chem.,Vol.276,No.9(2001.Mar.)p.6616-6620
Biochemistry,Vol.38,No.34(1999)p.10940-10948
Biochemistry,Vol.34,No.27(1995)p.8701-8707
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe